KEGG   Homo sapiens (human): 8476
Entry
8476              CDS       T01001                                 
Symbol
CDC42BPA, MRCK, MRCKA, MRCKalpha, PK428
Name
(RefSeq) CDC42 binding protein kinase alpha
  KO
K16307  serine/threonine-protein kinase MRCK [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    8476 (CDC42BPA)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     8476 (CDC42BPA)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: AGC group
  DMPK family [OT]
   8476 (CDC42BPA)
SSDB
Motif
Pfam: CNH Pkinase KELK PK_Tyr_Ser-Thr DMPK_coil C1_1 Pkinase_C PH PBD
Other DBs
NCBI-GeneID: 8476
NCBI-ProteinID: NP_003598
OMIM: 603412
HGNC: 1737
Ensembl: ENSG00000143776
UniProt: Q5VT25
Position
1:complement(226989858..227318492)
AA seq 1719 aa
MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNNSPLRREKNILEYLEWA
KPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETA
CFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARF
YLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGT
PDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKER
FQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIP
EVSSPTDTSNFDVDDDCLKNSETMPPPTHTAFSGHHLPFVGFTYTSSCVLSDRSCLRVTA
GPTSLDLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGP
LTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTL
QQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHV
RDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLE
NELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKK
ELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLT
SELDKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQA
LASKMTEELEALRNSSLGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEEL
NKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEELRSEKGIEHQDSQHSFLAFLNTP
TDALDQFETVDSTPLSVHTPTLRKKGCPGSTGFPPKRKTHQFFVKSFTTPTKCHQCTSLM
VGLIRQGCSCEVCGFSCHITCVNKAPTTCPVPPEQTKGPLGIDPQKGIGTAYEGHVRIPK
PAGVKKGWQRALAIVCDFKLFLYDIAEGKASQPSVVISQVIDMRDEEFSVSSVLASDVIH
ASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGVLSELHKILKKNKFRDRSV
YVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIEL
IPNDQLVAVISGRNRHVRLFPMSALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVA
MKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYS
MLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPS
SCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKN
KMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISN
PTNFNHIAHMGPGDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSG
LSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDS
PRHSTASNSSNLSSPPSPASPRKTKSLSLESTDRGSWDP
NT seq 5160 nt   +upstreamnt  +downstreamnt
atgtctggagaagtgcgtttgaggcagttggagcagtttattttggacgggcccgctcag
accaatgggcagtgcttcagtgtggagacattactggatatactcatctgcctttatgat
gaatgcaataattctccattgagaagagagaagaacattctcgaatacctagaatgggct
aaaccatttacttctaaagtgaaacaaatgcgattacatagagaagactttgaaatatta
aaggtgattggtcgaggagcttttggggaggttgctgtagtaaaactaaaaaatgcagat
aaagtgtttgccatgaaaatattgaataaatgggaaatgctgaaaagagctgagacagca
tgttttcgtgaagaaagggatgtattagtgaatggagacaataaatggattacaaccttg
cactatgctttccaggatgacaataacttatacctggttatggattattatgttggtggg
gatttgcttactctactcagcaaatttgaagatagattgcctgaagatatggctagattt
tacttggctgagatggtgatagcaattgactcagttcatcagctacattatgtacacaga
gacattaaacctgacaatatactgatggatatgaatggacatattcggttagcagatttt
ggttcttgtctgaagctgatggaagatggaacggttcagtcctcagtggctgtaggaact
ccagattatatctctcctgaaatccttcaagccatggaagatggaaaagggagatatgga
cctgaatgtgactggtggtctttgggggtctgtatgtatgaaatgctttacggagaaaca
ccattttatgcagaatcgctggtggagacatacggaaaaatcatgaaccacaaagagagg
tttcagtttccagcccaagtgactgatgtgtctgaaaatgctaaggatcttattcgaagg
ctcatttgtagcagagaacatcgacttggtcaaaatggaatagaagactttaagaaacac
ccatttttcagtggaattgattgggataatattcggaactgtgaagcaccttatattcca
gaagttagtagcccaacagatacatcgaattttgatgtagatgatgattgtttaaaaaat
tctgaaacgatgcccccaccaacacatactgcattttctggccaccatctgccatttgtt
ggttttacatatactagtagctgtgtactttctgatcggagctgtttaagagttacggct
ggtcccacctcactggatcttgatgttaatgttcagaggactctagacaacaacttagca
actgaagcttatgaaagaagaattaagcgccttgagcaagaaaaacttgaactcagtaga
aaacttcaagagtcaacacagactgtccaagctctgcagtattcaactgttgatggtcca
ctaacagcaagcaaagatttagaaataaaaaacttaaaagaagaaattgaaaaactaaga
aaacaagtaacagaatcaagtcatttggaacagcaacttgaagaagctaatgctgtgagg
caagaactagatgatgcttttagacaaatcaaggcttatgaaaaacaaatcaaaacgtta
caacaagaaagagaagatctaaataaggaactagtccaggctagtgagcgattaaaaaac
caatccaaagagctgaaagacgcacactgtcagaggaaactggccatgcaggaattcatg
gagatcaatgagcggctaacagaattgcacacccaaaaacagaaacttgctcgccatgtc
cgagataaggaagaagaggtggacctggtgatgcaaaaagttgaaagcttaaggcaagaa
ctgcgcagaacagaaagagccaaaaaagagctggaagttcatacagaagctctagctgct
gaagcatctaaagacaggaagctacgtgaacagagtgagcactattctaagcaactggaa
aatgaattggagggactgaagcaaaaacaaattagttactcaccaggagtatgcagcata
gaacatcagcaagagataaccaaactaaagactgatttggaaaagaaaagtatcttttat
gaagaagaattatctaaaagagaaggaatacatgcaaatgaaataaaaaatcttaagaaa
gaactgcatgattcagaaggtcagcaacttgctctcaacaaagaaattatgattttaaaa
gacaaattggaaaaaaccagaagagaaagtcaaagtgaaagggaggaatttgaaagtgag
ttcaaacaacaatatgaacgagaaaaagtgttgttaactgaagaaaataaaaagctgacg
agtgaacttgataagcttactactttgtatgagaacttaagtatacacaaccagcagtta
gaagaagaggttaaagatctagcagacaagaaagaatcagttgcacattgggaagcccaa
atcacagaaataattcagtgggtcagcgatgaaaaggatgcacgagggtatcttcaggcc
ttagcttctaaaatgactgaagaattggaggcattaagaaattccagcttgggtacacga
gcaacagatatgccctggaaaatgcgtcgttttgcgaaactggatatgtcagctagactg
gagttgcagtcggctctggatgcagaaataagagccaaacaggccatccaagaagagttg
aataaagttaaagcatctaatatcataacagaatgtaaactaaaagattcagagaagaag
aacttggaactactctcagaaatcgaacagctgataaaggacactgaagagcttagatct
gaaaagggtatagagcaccaagactcacagcattctttcttggcatttttgaatacgcct
accgatgctctggatcaatttgaaactgtagactccactccactttcagttcacacacca
accttaaggaaaaaaggatgtcctggttcaactggctttccacctaagcgcaagactcac
cagttttttgtaaaatcttttactactcctaccaagtgtcatcagtgtacctccttgatg
gtgggtttaataagacagggctgttcatgtgaagtgtgtggattctcatgccatataact
tgtgtaaacaaagctccaaccacttgtccagttcctcctgaacagacaaaaggtcccctg
ggtatagatcctcagaaaggaataggaacagcatatgaaggtcatgtcaggattcctaag
ccagctggagtgaagaaagggtggcagagagcactggctatagtgtgtgacttcaaactc
tttctgtacgatattgctgaaggaaaagcatctcagcccagtgttgtcattagtcaagtg
attgacatgagggatgaagaattttctgtgagttcagtcttggcttctgatgttatccat
gcaagtcggaaagatataccctgtatatttagggtcacagcttcccagctctcagcatct
aataacaaatgttcaatcctgatgctagcagacactgagaatgagaagaataagtgggtg
ggagtgctgagtgaattgcacaagattttgaagaaaaacaaattcagagaccgctcagtc
tatgttcccaaagaggcttatgacagcactctacccctcattaaaacaacccaggcagcc
gcaatcatagatcatgaaagaattgctttgggaaacgaagaagggttatttgttgtacat
gtcaccaaagatgaaattattagagttggtgacaataagaagattcatcagattgaactc
attccaaatgatcagcttgttgctgtgatctcaggacgaaatcgtcatgtacgacttttt
cctatgtcagcattggatgggcgagagaccgatttttacaagctgtcagaaactaaaggg
tgtcaaaccgtaacttctggaaaggtgcgccatggagctctcacatgcctgtgtgtggct
atgaaaaggcaggtcctctgttatgaactatttcagagcaagacccgtcacagaaaattt
aaagaaattcaagtcccatataatgtccagtggatggcaatcttcagtgaacaactctgt
gtgggattccagtcaggatttctaagataccccttgaatggagaaggaaatccatacagt
atgctccattcaaatgaccatacactatcatttattgcacatcaaccaatggatgctatc
tgcgcagttgagatctccagtaaagaatatctgctgtgttttaacagcattgggatatac
actgactgccagggccgaagatctagacaacaggaattgatgtggccagcaaatccttcc
tcttgttgttacaatgcaccatatctctcggtgtacagtgaaaatgcagttgatatcttt
gatgtgaactccatggaatggattcagactcttcctctcaaaaaggttcgacccttaaac
aatgaaggatcattaaatcttttagggttggagaccattagattaatatatttcaaaaat
aagatggcagaaggggacgaactggtagtacctgaaacatcagataatagtcggaaacaa
atggttagaaacattaacaataagcggcgttattccttcagagtcccagaagaggaaagg
atgcagcagaggagggaaatgctacgagatccagaaatgagaaataaattaatttctaat
ccaactaattttaatcacatagcacacatgggtcctggagatggaatacagatcctgaaa
gatctgcccatgaaccctcggcctcaggaaagtcggacagtattcagtggctcagtcagt
attccatctatcaccaaatcccgccctgagccaggccgctccatgagtgctagcagtggc
ttgtcagcaaggtcatccgcacagaatggcagcgcattaaagagggaattctctggagga
agctacagtgccaagcggcagcccatgccctccccgtcagagggctctttgtcctctgga
ggcatggaccaaggaagtgatgccccagcgagggactttgacggagaggactctgactct
ccgaggcattccacagcttccaacagttccaacctaagcagccccccaagcccagcttca
ccccgaaaaaccaagagcctctccctggagagcactgaccgcgggagctgggacccgtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (45)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (43)   
DNA sequence (79)   
   RefSeq(nuc) (43)   
   GenBank (18)   
   EMBL (18)   
Protein domain (9)   
   Pfam (9)   
All databases (156)   

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