KEGG   Homo sapiens (human): 84861
Entry
84861             CDS       T01001                                 
Symbol
KLHL22, KELCHL
Name
(RefSeq) kelch like family member 22
  KO
K10459  kelch-like protein 22
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    84861 (KLHL22)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul3 complex
    Adoptor and target recognizing subunit (BTB)
     84861 (KLHL22)
SSDB
Motif
Pfam: Kelch_1 Kelch_6 BTB Kelch_3 Kelch_2 Kelch_4 BACK KLHL33-like_BTB_POZ
Other DBs
NCBI-GeneID: 84861
NCBI-ProteinID: NP_116164
OMIM: 618020
HGNC: 25888
Ensembl: ENSG00000099910
UniProt: Q53GT1
Structure
Position
22:complement(20441519..20495795)
AA seq 634 aa
MAEEQEFTQLCKLPAQPSHPHCVNNTYRSAQHSQALLRGLLALRDSGILFDVVLVVEGRH
IEAHRILLAASCDYFRGMFAGGLKEMEQEEVLIHGVSYNAMCQILHFIYTSELELSLSNV
QETLVAACQLQIPEIIHFCCDFLMSWVDEENILDVYRLAELFDLSRLTEQLDTYILKNFV
AFSRTDKYRQLPLEKVYSLLSSNRLEVSCETEVYEGALLYHYSLEQVQADQISLHEPPKL
LETVRFPLMEAEVLQRLHDKLDPSPLRDTVASALMYHRNESLQPSLQSPQTELRSDFQCV
VGFGGIHSTPSTVLSDQAKYLNPLLGEWKHFTASLAPRMSNQGIAVLNNFVYLIGGDNNV
QGFRAESRCWRYDPRHNRWFQIQSLQQEHADLSVCVVGRYIYAVAGRDYHNDLNAVERYD
PATNSWAYVAPLKREVYAHAGATLEGKMYITCGRRGEDYLKETHCYDPGSNTWHTLADGP
VRRAWHGMATLLNKLYVIGGSNNDAGYRRDVHQVACYSCTSGQWSSVCPLPAGHGEPGIA
VLDNRIYVLGGRSHNRGSRTGYVHIYDVEKDCWEEGPQLDNSISGLAACVLTLPRSLLLE
PPRGTPDRSQADPDFASEVMSVSDWEEFDNSSED
NT seq 1905 nt   +upstreamnt  +downstreamnt
atggcagaggagcaggagttcacccagctctgcaagttgcctgcacagccctcacaccca
cactgcgtgaacaacacctaccgcagcgcacagcactcccaggctctgctccgagggctg
ctggctctccgggacagcggaatcctcttcgatgttgtgctggtggtggagggcagacac
atcgaggcccatcgcatcctgctggctgcgtcctgcgattacttcagaggaatgtttgct
gggggattgaaggagatggaacaggaagaggtcctgatccacggtgtgtcctacaatgct
atgtgccaaatcctacatttcatatacacctccgagctggagctcagcctgagcaatgta
caagagacactggtggctgcctgccagcttcagatcccagaaattatccatttctgctgt
gatttcctcatgtcctgggtggacgaagagaacattctcgatgtctaccggctggcagag
ctgtttgacttgagccgcctgactgagcaactggacacctatatcctcaaaaactttgtg
gccttctctcggactgacaagtaccgccagcttccattggagaaggtctactccctcctc
agcagcaatcgcctggaggtctcctgcgagaccgaggtatatgagggggcccttctctac
cattatagcctggagcaggtgcaggctgaccagatctcgctgcacgagcccccaaagctc
cttgagacagtgcggtttccgctgatggaagctgaggtcctgcagcggctgcatgacaag
ctggaccccagccctttgagggacacagtggccagcgccctcatgtaccaccggaacgag
agcctacagcccagcctgcagagcccgcaaacggagctgcggtcggacttccagtgcgtt
gtgggcttcgggggcattcactccacgccgtccactgtcctcagcgaccaggccaagtat
ctaaaccccttactgggagagtggaagcacttcactgcctccctggccccccgcatgtcc
aaccagggcatcgcggtgctcaacaacttcgtatacttgattggaggggacaacaatgtc
caaggatttcgagcagagtcccgatgctggaggtatgacccacggcacaaccgctggttc
cagatccagtccctgcagcaggagcacgccgacctgtccgtgtgtgttgtaggcaggtac
atctacgctgtggcgggccgtgactaccacaatgacctgaatgctgtggagcgctacgac
cctgccaccaactcctgggcatacgtggccccactcaagagggaggtgtatgcccacgca
ggcgcgacgctggaggggaagatgtatatcacctgcggccgcagaggggaggattacctg
aaagagacacactgctacgatccaggcagcaacacttggcacacactggctgatgggcct
gtgcggcgcgcctggcacggcatggcaaccctcctcaacaagctgtatgtgatcgggggc
agcaacaacgatgccggatacaggagggacgtgcaccaggtggcctgctacagctgcacg
tctggacagtggtcatctgtctgcccactccctgctgggcacggtgagcctggcattgct
gtgctggacaacaggatctatgtgttaggtggccgctcacacaaccgcggcagccgcaca
ggctacgtgcacatttacgatgtggagaaggactgctgggaggaagggccccagctggac
aactccatctcaggcctggcggcctgtgtgctcaccctgccccgctccctgctccttgag
ccgccccgcgggacccctgaccgcagccaggccgacccggactttgcctctgaggtgatg
agtgtgtctgactgggaggagtttgacaactccagtgaggactag

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Ontology (2)   
   KEGG BRITE (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (20)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (18)   
DNA sequence (38)   
   RefSeq(nuc) (22)   
   GenBank (8)   
   EMBL (8)   
3D Structure (1)   
   PDB (1)   
Protein domain (8)   
   Pfam (8)   
All databases (90)   

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