KEGG   Homo sapiens (human): 8491
Entry
8491              CDS       T01001                                 
Symbol
MAP4K3, GLK, MAPKKKK3, MEKKK_3, MEKKK3, RAB8IPL1
Name
(RefSeq) mitogen-activated protein kinase kinase kinase kinase 3
  KO
K04406  mitogen-activated protein kinase kinase kinase kinase 3 [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    8491 (MAP4K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    8491 (MAP4K3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     8491 (MAP4K3)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: STE group
  STE20 family
   8491 (MAP4K3)
SSDB
Motif
Pfam: Pkinase CNH PK_Tyr_Ser-Thr ABC1 Pkinase_fungal
Other DBs
NCBI-GeneID: 8491
NCBI-ProteinID: NP_003609
OMIM: 604921
HGNC: 6865
Ensembl: ENSG00000011566
UniProt: Q8IVH8 A8K602 B3KMM5
Structure
Position
2:complement(39249266..39437285)
AA seq 894 aa
MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQ
EIIMMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRET
LQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAP
EVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKM
KWSNSFHHFVKMALTKNPKKRPTAEKLLQHPFVTQHLTRSLAIELLDKVNNPDHSTYHDF
DDDDPEPLVAVPHRIHSTSRNVREEKTRSEITFGQVKFDPPLRKETEPHHELPDSDGFLD
SSEEIYYTARSNLDLQLEYGQGHQGGYFLGANKSLLKSVEEELHQRGHVAHLEDDEGDDD
ESKHSTLKAKIPPPLPPKPKSIFIPQEMHSTEDENQGTIKRCPMSGSPAKPSQVPPRPPP
PRLPPHKPVALGNGMSSFQLNGERDGSLCQQQNEHRGTNLSRKEKKDVPKPISNGLPPTP
KVHMGACFSKVFNGCPLKIHCASSWINPDTRDQYLIFGAEEGIYTLNLNELHETSMEQLF
PRRCTWLYVMNNCLLSISGKASQLYSHNLPGLFDYARQMQKLPVAIPAHKLPDRILPRKF
SVSAKIPETKWCQKCCVVRNPYTGHKYLCGALQTSIVLLEWVEPMQKFMLIKHIDFPIPC
PLRMFEMLVVPEQEYPLVCVGVSRGRDFNQVVRFETVNPNSTSSWFTESDTPQTNVTHVT
QLERDTILVCLDCCIKIVNLQGRLKSSRKLSSELTFDFQIESIVCLQDSVLAFWKHGMQG
RSFRSNEVTQEISDSTRIFRLLGSDRVVVLESRPTDNPTANSNLYILAGHENSY
NT seq 2685 nt   +upstreamnt  +downstreamnt
atgaaccccggcttcgatttgtcccgccggaacccgcaggaggacttcgagctgattcag
cgcatcggcagcggcacctacggcgacgtctacaaggcacggaatgttaacactggtgaa
ttagcagcaattaaagtaataaaattggaaccaggagaagactttgcagttgtgcagcaa
gaaattattatgatgaaagactgtaaacacccaaatattgttgcttattttggaagctat
ctcaggcgagataagctttggatttgcatggagttttgtggaggtggttctttacaggat
atttatcacgtaactggacctctgtcagaactgcaaattgcatatgttagcagagaaaca
ctgcagggattatattatcttcacagtaaaggaaaaatgcacagagatataaagggagct
aacattctattaacggataatggtcatgtgaaattggctgattttggagtatctgcacag
ataacagctacaattgccaaacggaagtctttcattggcacaccatattggatggctcca
gaagttgcagctgttgagaggaaggggggttacaatcaactctgtgatctctgggcagtg
ggaatcactgccatagaacttgcagagcttcagcctcctatgtttgacttacacccaatg
agagcattatttctaatgacaaaaagcaattttcagcctcctaaactaaaggataaaatg
aaatggtcaaatagttttcatcactttgtgaaaatggcacttaccaaaaatccgaaaaaa
agacctactgctgaaaaattattacagcatccttttgtaacacaacatttgacacggtct
ttggcaatcgagctgttggataaagtaaataatccagatcattccacttaccatgatttc
gatgatgatgatcctgagcctcttgttgctgtaccacatagaattcactcaacaagtaga
aacgtgagagaagaaaaaacacgctcagagataacctttggccaagtgaaatttgatcca
cccttaagaaaggagacagaaccacatcatgaacttcccgacagtgatggttttttggac
agttcagaagaaatatactacactgcaagatctaatctggatctgcaactggaatatgga
caaggacaccaaggtggttactttttaggtgcaaacaagagtcttctcaagtctgttgaa
gaagaattgcatcagcgaggacacgtcgcacatttagaagatgatgaaggagatgatgat
gaatctaaacactcaactctgaaagcaaaaattccacctcctttgccaccaaagcctaag
tctatcttcataccacaggaaatgcattctactgaggatgaaaatcaaggaacaatcaag
agatgtcccatgtcagggagcccagcaaagccatcccaagttccacctagaccaccacct
cccagattacccccacacaaacctgttgccttaggaaatggaatgagctccttccagtta
aatggtgaacgagatggctcattatgtcaacaacagaatgaacatagaggcacaaacctt
tcaagaaaagaaaagaaagatgtaccaaagcctattagtaatggtcttcctccaacacct
aaagtgcatatgggtgcatgtttttcaaaagtttttaatgggtgtcccttgaaaattcac
tgtgcatcatcatggataaacccagatacaagagatcagtacttgatatttggtgccgaa
gaagggatttataccctcaatcttaatgaacttcatgaaacatcaatggaacagctattc
cctcgaaggtgtacatggttgtatgtaatgaacaattgcttgctatcaatatctggtaaa
gcttctcagctttattcccataatttaccagggctttttgattatgcaagacaaatgcaa
aagttacctgttgctattccagcacacaaactccctgacagaatactgccaaggaaattt
tctgtatcagcaaaaatccctgaaaccaaatggtgccagaagtgttgtgttgtaagaaat
ccttacacgggccataaatacctatgtggagcacttcagactagcattgttctattagaa
tgggttgaaccaatgcagaaatttatgttaattaagcacatagattttcctataccatgt
ccacttagaatgtttgaaatgctggtagttcctgaacaggagtaccctttagtttgtgtt
ggtgtcagtagaggtagagacttcaaccaagtggttcgatttgagacggtcaatccaaat
tctacctcttcatggtttacagaatcagataccccacagacaaatgttactcatgtaacc
caactggagagagataccatccttgtatgcttggactgttgtataaaaatagtaaatctc
caaggaagattaaaatctagcaggaaattgtcatcagaactcacctttgatttccagatt
gaatcaatagtgtgcctacaagacagtgtgctagctttctggaaacatggaatgcaaggt
agaagttttagatctaatgaggtaacacaagaaatttcagatagcacaagaattttcagg
ctgcttggatctgacagggtcgtggttttggaaagtaggccaactgataaccccacagca
aatagcaatttgtacatcctggcgggtcatgaaaacagttactga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (13)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (25)   
   RefSeq(nuc) (9)   
   GenBank (8)   
   EMBL (8)   
3D Structure (1)   
   PDB (1)   
Protein domain (5)   
   Pfam (5)   
All databases (72)   

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