KEGG   Homo sapiens (human): 84971
Entry
84971             CDS       T01001                                 
Symbol
ATG4D, APG4-D, APG4D, AUTL4, HsAPG4D
Name
(RefSeq) autophagy related 4D cysteine peptidase
  KO
K08342  cysteine protease ATG4 [EC:3.4.22.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04136  Autophagy - other
hsa04140  Autophagy - animal
Network
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06182  Shigella
nt06532  Autophagy
  Element
N00156  Autophagy-vesicle nucleation/elongation/maturation, LC3-II formation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    84971 (ATG4D)
   04136 Autophagy - other
    84971 (ATG4D)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    84971 (ATG4D)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    84971 (ATG4D)
   03029 Mitochondrial biogenesis [BR:hsa03029]
    84971 (ATG4D)
Peptidases and inhibitors [BR:hsa01002]
 Cysteine peptidases
  Family C54: Aut2 peptidase family
   84971 (ATG4D)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Autophagosome formation proteins
   Atg8 conjugation proteins
    84971 (ATG4D)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Autophagy-related proteins
    84971 (ATG4D)
SSDB
Motif
Pfam: Peptidase_C54
Other DBs
NCBI-GeneID: 84971
NCBI-ProteinID: NP_116274
OMIM: 611340
HGNC: 20789
Ensembl: ENSG00000130734
UniProt: Q86TL0
Position
19:10543904..10553418
AA seq 474 aa
MNSVSPAAAQYRSSSPEDARRRPEARRPRGPRGPDPNGLGPSGASGPALGSPGAGPSEPD
EVDKFKAKFLTAWNNVKYGWVVKSRTSFSKISSIHLCGRRYRFEGEGDIQRFQRDFVSRL
WLTYRRDFPPLPGGCLTSDCGWGCMLRSGQMMLAQGLLLHFLPRDWTWAEGMGLGPPELS
GSASPSRYHGPARWMPPRWAQGAPELEQERRHRQIVSWFADHPRAPFGLHRLVELGQSSG
KKAGDWYGPSLVAHILRKAVESCSDVTRLVVYVSQDCTVYKADVARLVARPDPTAEWKSV
VILVPVRLGGETLNPVYVPCVKELLRCELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYC
QPTVDVSQADFPLESFHCTSPRKMAFAKMDPSCTVGFYAGDRKEFETLCSELTRVLSSSS
ATERYPMFTLAEGHAQDHSLDDLCSQLAQPTLRLPRTGRLLRAKRPSSEDFVFL
NT seq 1425 nt   +upstreamnt  +downstreamnt
atgaactcagtgtcgccggccgccgcgcagtaccggagcagcagcccggaggacgcgcgc
cgccggcccgaggcccgcaggccgcggggtcccagaggcccagaccccaacggcctgggg
ccttccggagccagcggccccgctcttggctctcccggggctggcccgagtgagccggac
gaagtggacaagttcaaggccaagttcctgacagcctggaacaacgtcaagtacggttgg
gtggttaaaagccggaccagctttagcaagatctccagcatccacctctgtggccgccgc
taccgtttcgagggcgagggtgacatacagcgtttccagcgggactttgtgtcccgcctg
tggctcacataccgccgggacttcccgccccttcctgggggctgcctgacctcggactgt
ggctgggggtgcatgttacgcagcggccagatgatgctggcacagggccttctgctgcat
ttcctgcccagagactggacatgggccgagggcatgggcctgggcccccctgagctgtca
gggtcagcctctcccagccggtaccatgggcctgcccgctggatgcccccacgctgggcc
cagggtgcccctgagctggagcaggaacgccggcaccggcagattgtgtcctggttcgcc
gaccacccccgggccccctttggcctacaccggctggtggagcttgggcagagctcaggc
aagaaggcaggtgactggtatgggccatcgctagtggcacacatcctcaggaaagccgtg
gagagctgctccgacgtcacccgcctggtggtgtacgtttctcaggactgcacagtgtac
aaggcggatgtggcacgcctggtggccaggccagaccccacagccgagtggaagtctgtg
gtcatcctggtgcccgtgcgactgggtggcgagactctcaaccccgtgtatgtgccctgc
gtgaaggaactcctgcgttgcgagctgtgcctgggcatcatgggtgggaaaccgcgacac
tcactgtacttcattggctaccaagatgacttcctgctgtacctggaccctcactactgc
cagcccactgtggatgtcagccaggccgacttccccctggagtccttccactgcacctcg
ccccgcaagatggcctttgccaagatggacccaagctgtaccgtgggcttctatgctgga
gacaggaaggagtttgagacactctgctcagagctgaccagggtcctcagctcctcctca
gccacagagcggtaccccatgttcaccctggccgagggccatgctcaggaccacagcctg
gacgacctctgctcccagctcgcccagcccacactccggctccctcgcacagggcggctc
ctcagggccaaacgccccagctctgaggactttgtgtttttataa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (4)   
   KEGG NETWORK (4)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (28)   
   RefSeq(nuc) (6)   
   GenBank (11)   
   EMBL (11)   
Protein domain (1)   
   Pfam (1)   
All databases (63)   

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