KEGG   Homo sapiens (human): 8509
Entry
8509              CDS       T01001                                 
Symbol
NDST2, HSST2, N-HSST_2, NST2
Name
(RefSeq) N-deacetylase and N-sulfotransferase 2
  KO
K02577  heparan sulfate N-deacetylase/N-sulfotransferase NDST2 [EC:3.5.1.- 2.8.2.8]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00534  Glycosaminoglycan biosynthesis - heparan sulfate / heparin
hsa01100  Metabolic pathways
Module
hsa_M00059  Glycosaminoglycan biosynthesis, heparan sulfate backbone
Network
nt06029  Glycosaminoglycan biosynthesis
  Element
N01582  Heparan sulfate biosynthesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
    8509 (NDST2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:hsa01003]
    8509 (NDST2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.8  Transferring sulfur-containing groups
   2.8.2  Sulfotransferases
    2.8.2.8  [heparan sulfate]-glucosamine N-sulfotransferase
     8509 (NDST2)
Glycosyltransferases [BR:hsa01003]
 Unclassified
  Sulfotransferases
   8509 (NDST2)
SSDB
Motif
Pfam: HSNSD Sulfotransfer_1 Sulfotransfer_3
Other DBs
NCBI-GeneID: 8509
NCBI-ProteinID: NP_003626
OMIM: 603268
HGNC: 7681
Ensembl: ENSG00000166507
UniProt: P52849 B4E139
Position
10:complement(73801916..73811820)
AA seq 883 aa
MLQLWKVVRPARQLELHRLILLLIAFSLGSMGFLAYYVSTSPKAKEPLPLPLGDCSSGGA
AGPGPARPPVPPRPPRPPETARTEPVVLVFVESAYSQLGQEIVAILESSRFRYSTELAPG
RGDMPTLTDNTHGRYVLVIYENLLKYVNLDAWSRELLDRYCVEYGVGIIGFFRAHEHSLL
SAQLKGFPLFLHSNLGLRDYQVNPSAPLLHLTRPSRLEPGPLPGDDWTIFQSNHSTYEPV
LLASLRPAEPAVPGPVLRRARLPTVVQDLGLHDGIQRVLFGHGLSFWLHKLIFVDAVAYL
TGKRLCLDLDRYILVDIDDIFVGKEGTRMKVADVEALLTTQNKLRTLVPNFTFNLGFSGK
FYHTGTEEEDAGDDMLLKHRKEFWWFPHMWSHMQPHLFHNRSVLADQMRLNKQFALEHGI
PTDLGYAVAPHHSGVYPIHTQLYEAWKSVWGIQVTSTEEYPHLRPARYRRGFIHNGIMVL
PRQTCGLFTHTIFYNEYPGGSRELDRSIRGGELFLTVLLNPISIFMTHLSNYGNDRLGLY
TFESLVRFLQCWTRLRLQTLPPVPLAQKYFELFPQERSPLWQNPCDDKRHKDIWSKEKTC
DRLPKFLIVGPQKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHKGIDWYMDF
FPVPSNASTDFLFEKSATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSWYQHQRAHG
DPVALNYTFYQVISASSQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIVDGQEL
RTNPAASMESIQKFLGITPFLNYTRTLRFDDDKGFWCQGLEGGKTRCLGRSKGRRYPDMD
TESRLFLTDFFRNHNLELSKLLSRLGQPVPSWLREELQHSSLG
NT seq 2652 nt   +upstreamnt  +downstreamnt
atgctccagttgtggaaggtggtacgcccagctcggcagctggaactgcaccgcctcata
ctgctgctgatcgctttcagcctgggctccatgggcttcctggcttattatgtgtccacc
agccctaaggccaaggaacccttgcccctgcccttgggagactgcagcagcggtggggca
gctggtcctggccctgcacggcctccagttccacctcggccccccaggcctccagagaca
gctcgaactgaacccgtggtccttgtgtttgtggagagtgcatactcacagctggggcag
gaaattgtggccatcctggagtctagtcgttttcgttatagcactgagttggcacctggc
cgaggggacatgcccacattgactgataatacccatggccgctatgtcttggtcatttat
gagaacctgctcaagtatgtcaacctggatgcctggagtcgggaactgctagaccggtac
tgcgtggagtatggtgtgggcatcattggctttttccgagcccacgagcacagcctactg
agcgcccagctcaagggctttcccctttttttacactcaaacttggggctccgggactac
caagtgaatccttctgccccgctactgcatctcacacgccccagccgcctagaaccaggg
ccactgcctggtgatgactggaccatcttccaatccaatcatagtacatatgaaccagtg
cttcttgccagccttcggccagctgagcccgcagtgccaggaccagttcttcgtcgggcc
cggcttcccactgtggtacaggacctggggcttcatgatggcatccagcgggtgctcttt
ggacatggcctttccttctggctccacaaacttatcttcgttgatgctgttgcatacctc
actggcaagcgcctctgcctggaccttgaccgctacatcttggtagacatcgatgacatc
tttgtgggcaaggaagggacccgcatgaaggtggctgatgttgaggctctgttgaccacc
cagaacaaactcaggaccttagttcccaacttcaccttcaacttgggcttctcgggcaag
ttctatcatactgggacagaggaggaggatgcaggggacgacatgctgctgaagcaccgc
aaagagttctggtggttcccccacatgtggagccacatgcagccacacctgttccacaat
cgctccgtgctggctgaccagatgaggctcaacaaacagtttgctctggagcatgggatt
cccacggacctggggtatgctgtggccccccaccactcgggtgtgtaccccatccacacg
cagctctatgaggcctggaaatccgtgtggggcatccaggtgaccagcactgaggagtat
ccccatctccgccctgcccgctaccgccgtggcttcattcacaatggcattatggtgctg
ccccggcagacatgtggcctcttcactcacacaatcttctataatgagtatcctggaggc
tctcgtgaactagaccggagcatccgaggtggagagctctttctgacagtgctgcttaat
ccgatcagcatctttatgacccatctgtccaattatggaaatgaccggctgggcctatac
acctttgagagcttggtgcgcttcctccagtgttggacacggctgcgcctacagaccctt
cctcctgtcccacttgcacagaagtactttgaacttttccctcaggagcgaagccccctt
tggcagaatccctgtgatgacaagaggcacaaagatatctggtccaaggagaaaacctgt
gatcgtctcccgaagttcctcattgtgggaccccagaaaacagggactacagctattcac
ttcttcctgagcctgcacccagctgtaactagcagcttccctagccccagcacatttgag
gagattcagttcttcaacagccctaattaccacaagggtattgactggtacatggatttc
ttccctgttccttccaatgccagcactgatttcctatttgaaaaaagtgccacctacttt
gactctgaagttgtaccacggcggggggctgccctcctgccacgagccaagatcatcaca
gtgctcaccaaccctgctgacagggcctactcctggtaccagcatcagcgagcccatgga
gacccagttgctctgaactataccttctatcaggtgatttcagcctcctcccagacccct
ctggcactacgctccctgcagaaccgctgtcttgtccctggctactattctacccatcta
caacgctggctgacttactacccctctggacagttgctgattgtggatgggcaagagctg
cgtaccaacccagcagcctcaatggagagcatccagaagttcctgggtatcacacccttt
ctgaactacacacggaccctcaggtttgatgatgataagggattttggtgccagggactt
gaaggtggtaagactcgctgtctaggccggagcaaaggccggaggtatccagatatggac
actgagtcccgtcttttccttacggattttttccggaaccataatttggagttgtcgaag
ctgctgagccggcttggacagccagtgccctcgtggcttcgggaagaactgcagcattcc
agtctgggctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (39)   
   RefSeq(nuc) (5)   
   GenBank (17)   
   EMBL (17)   
Protein domain (3)   
   Pfam (3)   
All databases (82)   

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