KEGG   Homo sapiens (human): 8525
Entry
8525              CDS       T01001                                 
Symbol
DGKZ, DAGK5, DAGK6, DGK-ZETA, hDGKzeta
Name
(RefSeq) diacylglycerol kinase zeta
  KO
K00901  diacylglycerol kinase (ATP) [EC:2.7.1.107]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00561  Glycerolipid metabolism
hsa00564  Glycerophospholipid metabolism
hsa01100  Metabolic pathways
hsa04070  Phosphatidylinositol signaling system
hsa04072  Phospholipase D signaling pathway
hsa05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    8525 (DGKZ)
   00564 Glycerophospholipid metabolism
    8525 (DGKZ)
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    8525 (DGKZ)
   04072 Phospholipase D signaling pathway
    8525 (DGKZ)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    8525 (DGKZ)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.107  diacylglycerol kinase (ATP)
     8525 (DGKZ)
SSDB
Motif
Pfam: DAGK_acc DAGK_cat Ank_2 Ank_4 Ank Ank_3 C1_1 Ank_5
Other DBs
NCBI-GeneID: 8525
NCBI-ProteinID: NP_001186196
OMIM: 601441
HGNC: 2857
Ensembl: ENSG00000149091
UniProt: Q13574
Structure
Position
11:46332926..46380554
AA seq 928 aa
MEPRDGSPEARSSDSESASASSSGSERDAGPEPDKAPRRLNKRRFPGLRLFGHRKAITKS
GLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGEQYCVAR
MLKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQ
DGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVI
PPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFV
NPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWI
LSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWD
LHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRN
KMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPW
GHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSKAIPVQVD
GEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALH
YDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLDA
TTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTSPCSPTPR
SLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVR
YLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEK
AQDTELAAYLENRQHYQMIQREDQETAV
NT seq 2787 nt   +upstreamnt  +downstreamnt
atggagccgcgggacggtagccccgaggcccggagcagcgactccgagtcggcttccgcc
tcgtccagcggctccgagcgcgacgccggtcccgagccggacaaggcgccgcggcgactc
aacaagcggcgcttcccggggctgcggctcttcgggcacaggaaagccatcaccaagtcg
ggcctccagcacctggccccccctccgcccacccctggggccccgtgcagcgagtcagag
cggcagatccggagtacagtggactggagcgagtcagcgacatatggggagcacatctgg
ttcgagaccaacgtgtccggggacttctgctacgttggggagcagtactgtgtagccagg
atgctgaagtcagtgtctcgaagaaagtgcgcagcctgcaagattgtggtgcacacgccc
tgcatcgagcagctggagaagataaatttccgctgtaagccgtccttccgtgaatcaggc
tccaggaatgtccgcgagccaacctttgtacggcaccactgggtacacagacgacgccag
gacggcaagtgtcggcactgtgggaagggattccagcagaagttcaccttccacagcaag
gagattgtggccatcagctgctcgtggtgcaagcaggcataccacagcaaggtgtcctgc
ttcatgctgcagcagatcgaggagccgtgctcgctgggggtccacgcagccgtggtcatc
ccgcccacctggatcctccgcgcccggaggccccagaatactctgaaagcaagcaagaag
aagaagagggcatccttcaagaggaagtccagcaagaaagggcctgaggagggccgctgg
agacccttcatcatcaggcccaccccctccccgctcatgaagcccctgctggtgtttgtg
aaccccaagagtgggggcaaccagggtgcaaagatcatccagtctttcctctggtatctc
aatccccgacaagtcttcgacctgagccagggagggcccaaggaggcgctggagatgtac
cgcaaagtgcacaacctgcggatcctggcgtgcgggggcgacggcacggtgggctggatc
ctctccaccctggaccagctacgcctgaagccgccaccccctgttgccatcctgcccctg
ggtactggcaacgacttggcccgaaccctcaactggggtgggggctacacagatgagcct
gtgtccaagatcctctcccacgtggaggaggggaacgtggtacagctggaccgctgggac
ctccacgctgagcccaaccccgaggcagggcctgaggaccgagatgaaggcgccaccgac
cggttgcccctggatgtcttcaacaactacttcagcctgggctttgacgcccacgtcacc
ctggagttccacgagtctcgagaggccaacccagagaaattcaacagccgctttcggaat
aagatgttctacgccgggacagctttctctgacttcctgatgggcagctccaaggacctg
gccaagcacatccgagtggtgtgtgatggaatggacttgactcccaagatccaggacctg
aaaccccagtgtgttgttttcctgaacatccccaggtactgtgcgggcaccatgccctgg
ggccaccctggggagcaccacgactttgagccccagcggcatgacgacggctacctcgag
gtcattggcttcaccatgacgtcgttggccgcgctgcaggtgggcggacacggcgagcgg
ctgacgcagtgtcgcgaggtggtgctcaccacatccaaggccatcccggtgcaggtggat
ggcgagccctgcaagcttgcagcctcacgcatccgcatcgccctgcgcaaccaggccacc
atggtgcagaaggccaagcggcggagcgccgcccccctgcacagcgaccagcagccggtg
ccagagcagttgcgcatccaggtgagtcgcgtcagcatgcacgactatgaggccctgcac
tacgacaaggagcagctcaaggaggcctctgtgccgctgggcactgtggtggtcccagga
gacagtgacctagagctctgccgtgcccacattgagagactccagcaggagcccgatggt
gctggagccaagtccccgacatgccagaaactgtcccccaagtggtgcttcctggacgcc
accactgccagccgcttctacaggatcgaccgagcccaggagcacctcaactatgtgact
gagatcgcacaggatgagatttatatcctggaccctgagctgctgggggcatcggcccgg
cctgacctcccaacccccacttcccctctccccacctcaccctgctcacccacgccccgg
tcactgcaaggggatgctgcaccccctcaaggtgaagagctgattgaggctgccaagagg
aacgacttctgtaagctccaggagctgcaccgagctgggggcgacctcatgcaccgagac
gagcagagtcgcacgctcctgcaccacgcagtcagcactggcagcaaggatgtggtccgc
tacctgctggaccacgcccccccagagatccttgatgcggtggaggaaaacggggagacc
tgtttgcaccaagcagcggccctgggccagcgcaccatctgccactacatcgtggaggcc
ggggcctcgctcatgaagacagaccagcagggcgacactccccggcagcgggctgagaag
gctcaggacaccgagctggccgcctacctggagaaccggcagcactaccagatgatccag
cgggaggaccaggagacggctgtgtag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (6)   
Disease (1)   
   OMIM (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (32)   
   KEGG ORTHOLOGY (1)   
   RefGene (22)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (51)   
   RefSeq(nuc) (7)   
   GenBank (22)   
   EMBL (22)   
3D Structure (1)   
   PDB (1)   
Protein domain (8)   
   Pfam (8)   
All databases (117)   

Download RDF
DBGET integrated database retrieval system