KEGG   Homo sapiens (human): 8692
Entry
8692              CDS       T01001                                 
Symbol
HYAL2, LUCA2
Name
(RefSeq) hyaluronidase 2
  KO
K01197  hyaluronoglucosaminidase [EC:3.2.1.35]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00531  Glycosaminoglycan degradation
hsa01100  Metabolic pathways
hsa04142  Lysosome
Module
hsa_M00076  Dermatan sulfate degradation
hsa_M00077  Chondroitin sulfate degradation
Network
nt06012  Glycosaminoglycan degradation
  Element
N00610  Dermatan sulfate degradation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00531 Glycosaminoglycan degradation
    8692 (HYAL2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    8692 (HYAL2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02042 Bacterial toxins [BR:hsa02042]
    8692 (HYAL2)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    8692 (HYAL2)
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
    8692 (HYAL2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.35  hyaluronoglucosaminidase
     8692 (HYAL2)
Bacterial toxins [BR:hsa02042]
 Toxins that damage the extracellular matrix
  Hyaluronidases/Collagenases
   8692 (HYAL2)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate / Heparin
  Enzymes
   8692 (HYAL2)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
 Enzymes
  8692 (HYAL2)
SSDB
Motif
Pfam: Glyco_hydro_56 EGF
Other DBs
NCBI-GeneID: 8692
NCBI-ProteinID: NP_003764
OMIM: 603551
HGNC: 5321
Ensembl: ENSG00000068001
UniProt: Q12891
Position
3:complement(50317808..50322745)
AA seq 473 aa
MRAGPGPTVTLALVLAVSWAMELKPTAPPIFTGRPFVVAWDVPTQDCGPRLKVPLDLNAF
DVQASPNEGFVNQNITIFYRDRLGLYPRFDSAGRSVHGGVPQNVSLWAHRKMLQKRVEHY
IRTQESAGLAVIDWEDWRPVWVRNWQDKDVYRRLSRQLVASRHPDWPPDRIVKQAQYEFE
FAAQQFMLETLRYVKAVRPRHLWGFYLFPDCYNHDYVQNWESYTGRCPDVEVARNDQLAW
LWAESTALFPSVYLDETLASSRHGRNFVSFRVQEALRVARTHHANHALPVYVFTRPTYSR
RLTGLSEMDLISTIGESAALGAAGVILWGDAGYTTSTETCQYLKDYLTRLLVPYVVNVSW
ATQYCSRAQCHGHGRCVRRNPSASTFLHLSTNSFRLVPGHAPGEPQLRPVGELSWADIDH
LQTHFRCQCYLGWSGEQCQWDHRQAAGGASEAWAGSHLTSLLALAALAFTWTL
NT seq 1422 nt   +upstreamnt  +downstreamnt
atgcgggcaggcccaggccccaccgttacattggccctggtgctggcggtgtcatgggcc
atggagctcaagcccacagcaccacccatcttcactggccggccctttgtggtagcgtgg
gacgtgcccacacaggactgtggcccacgcctcaaggtgccactggacctgaatgccttt
gatgtgcaggcctcacctaatgagggttttgtgaaccagaatattaccatcttctaccgc
gaccgtctaggcctgtatccacgcttcgattctgccggaaggtctgtgcatggtggtgtg
ccacagaatgtcagcctttgggcacaccggaagatgctgcagaaacgtgtggagcactac
attcggacacaggagtctgcggggctggcggtcatcgactgggaggactggcgacctgtg
tgggtgcgcaactggcaggacaaagatgtgtatcgccggttatcacgccagctagtggcc
agtcgtcaccctgactggcctccagaccgcatagtcaaacaggcacaatatgagtttgag
ttcgcagcacagcagttcatgctggagacactgcgttatgtcaaggcagtgcggccccgg
cacctctggggcttctacctctttcctgactgctacaatcatgattatgtgcagaactgg
gagagctacacaggccgctgccctgatgttgaggtggcccgcaatgaccagctggcctgg
ctgtgggctgagagcacggccctcttcccgtctgtctacctggacgagacacttgcttcc
tcccgccatggccgcaactttgtgagcttccgtgttcaggaggcccttcgtgtggctcgc
acccaccatgccaaccatgcactcccagtctacgtcttcacacgacccacctacagccgc
aggctcacggggcttagtgagatggacctcatctctaccattggcgagagtgcggccctg
ggcgcagctggtgtcatcctctggggtgacgcggggtacaccacaagcacggagacctgc
cagtacctcaaagattacctgacacggctgctggtcccctacgtggtcaatgtgtcctgg
gccacccaatattgcagccgggcccagtgccatggccatgggcgctgtgtgcgccgcaac
cccagtgccagtaccttcctgcatctcagcaccaacagtttccgcctagtgcctggccat
gcacctggtgaaccccagctgcgacctgtgggggagctcagttgggccgacattgaccac
ctgcagacacacttccgctgccagtgctacttgggctggagtggtgagcaatgccagtgg
gaccataggcaggcagctggaggtgccagcgaggcctgggctgggtcccacctcaccagt
ctgctggctctggcagccctggcctttacctggaccttgtag

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (34)   
   RefSeq(nuc) (6)   
   GenBank (14)   
   EMBL (14)   
Protein domain (2)   
   Pfam (2)   
All databases (80)   

Download RDF
DBGET integrated database retrieval system