KEGG T01001: 8732

Homo sapiens (human): 8732

Entry

8732              CDS       T01001

Symbol

RNGTT, CAP1A, HCE, HCE1, hCAP

Name

(RefSeq) RNA guanylyltransferase and 5'-phosphatase

K13917

mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]

Organism

hsa Homo sapiens (human)

Pathway

hsa03015

mRNA surveillance pathway

Brite

KEGG Orthology (KO) [BR:hsa00001]
09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    8732 (RNGTT)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    8732 (RNGTT)
Enzymes [BR:hsa01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.50  mRNA guanylyltransferase
     8732 (RNGTT)
3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.74  mRNA 5'-phosphatase
     8732 (RNGTT)
Messenger RNA biogenesis [BR:hsa03019]
Eukaryotic type
  mRNA processing factors
   5' end processing
    Capping factors
     8732 (RNGTT)

SSDB

Motif

Pfam:

mRNA_cap_enzyme mRNA_cap_C DSPc DNA_ligase_A_M Y_phosphatase Y_phosphatase2

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

Position

6:complement(88609897..88963618)

AA seq 597 aa
MAHNKIPPRWLNCPRRGQPVAGRFLPLKTMLGPRYDSQVAEENRFHPSMLSNYLKSLKVK
MGLLVDLTNTSRFYDRNDIEKEGIKYIKLQCKGHGECPTTENTETFIRLCERFNERNPPE
LIGVHCTHGFNRTGFLICAFLVEKMDWSIEAAVATFAQARPPGIYKGDYLKELFRRYGDI
EEAPPPPLLPDWCFEDDEDEDEDEDGKKESEPGSSASFGKRRKERLKLGAIFLEGVTVKG
VTQVTTQPKLGEVQQKCHQFCGWEGSGFPGAQPVSMDKQNIKLLDLKPYKVSWKADGTRY
MMLIDGTNEVFMIDRDNSVFHVSNLEFPFRKDLRMHLSNTLLDGEMIIDRVNGQAVPRYL
IYDIIKFNSQPVGDCDFNVRLQCIEREIISPRHEKMKTGLIDKTQEPFSVRNKPFFDICT
SRKLLEGNFAKEVSHEMDGLIFQPTGKYKPGRCDDILKWKPPSLNSVDFRLKITRMGGEG
LLPQNVGLLYVGGYERPFAQIKVTKELKQYDNKIIECKFENNSWVFMRQRTDKSFPNAYN
TAMAVCNSISNPVTKEMLFEFIDRCTAASQGQKRKHHLDPDTELMPPPPPKRPRPLT

NT seq 1794 nt +upstreamnt +downstreamnt
atggctcacaacaagatcccgccgcggtggctgaactgtccccggcgcggccagccggtg
gcaggaagattcttacctctgaagacaatgttaggaccaagatatgatagtcaagttgct
gaagaaaatcggttccatcccagcatgctctcaaattacctaaagagcctaaaggttaaa
atgggcttgttggtggacctgacaaatacttcaaggttctatgaccgaaatgacatagaa
aaagaaggaatcaaatatataaaacttcagtgtaaaggacatggtgagtgccctaccact
gagaatactgagacctttattcgtctgtgtgagcggtttaatgaaagaaatccacctgaa
cttataggtgttcattgtactcatggcttcaatcgcactggtttcctcatatgtgccttt
ttggtggagaaaatggattggagtatcgaagcagcagttgctacttttgcccaagccaga
ccaccaggaatctacaagggtgattatttgaaggaactttttcgtcggtatggtgacata
gaggaagcaccacccccacctctattgccagattggtgttttgaggatgatgaagacgaa
gatgaggatgaggatggaaagaaggaatcagaacccgggtcaagtgcttcttttggcaaa
aggagaaaagaacggttaaaactgggcgctattttcttggaaggtgttactgttaaaggt
gtaactcaagtaacaacacaaccaaagttaggagaggtacagcagaagtgtcatcaattc
tgtggctgggaagggtctggattccctggagcacagcctgtttccatggacaagcaaaat
attaaacttttagacctgaagccatacaaagtaagctggaaagcagatggtactcggtac
atgatgttgattgatggcacaaatgaagtttttatgattgatagagacaattcagtattt
catgtttcaaatctggaatttccatttcgtaaagatcttcgtatgcatttatcaaatact
ctcttggatggcgagatgattattgacagagtaaatggacaggctgttcctagatatttg
atatatgacataattaaattcaattcacagcccgttggagattgtgattttaatgttcgt
ctgcagtgtatagaacgagaaattataagtcctcgacacgaaaaaatgaagactgggctc
attgacaaaacacaggaaccatttagcgtcagaaataagccgttttttgacatctgtact
tcaagaaagctacttgaaggaaattttgccaaagaagtgagccatgaaatggatggactt
atttttcagcctactggaaaatacaaacctggtcgatgtgatgatattttgaaatggaag
cctcccagtctgaattctgtggattttcgtctaaaaataacaagaatgggaggagaaggg
ttacttcctcagaatgttggcctcctgtatgttggaggttatgaaagaccctttgcacaa
atcaaggtgacaaaagagctgaaacagtatgacaacaaaattatagaatgcaaatttgag
aacaacagctgggtcttcatgagacagagaacagacaaaagttttcctaatgcctacaac
actgccatggctgtgtgtaacagcatctcaaaccctgtcaccaaggagatgctgtttgag
ttcatcgacagatgtactgcagcttctcaaggacagaagcgaaaacatcatctggaccct
gacacggagctcatgccaccaccacctcccaaaagaccacgccctttaacctaa

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