KEGG   Homo sapiens (human): 8808
Entry
8808              CDS       T01001                                 
Symbol
IL1RL2, IL-1Rrp2, IL-36R, IL1R-rp2, IL1RRP2
Name
(RefSeq) interleukin 1 receptor like 2
  KO
K05172  interleukin 1 receptor-like 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04060  Cytokine-cytokine receptor interaction
Drug target
Imsidolimab: D11892
Spesolimab: D12066<JP/US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    8808 (IL1RL2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:hsa04050]
    8808 (IL1RL2)
Cytokine receptors [BR:hsa04050]
 Interleukin receptor families
  IL1 receptor family
   8808 (IL1RL2)
SSDB
Motif
Pfam: TIR Ig_2 Ig_3 I-set V-set ig Ig_6 Ig_4 TIR_2 C1-set
Other DBs
NCBI-GeneID: 8808
NCBI-ProteinID: NP_003845
OMIM: 604512
HGNC: 5999
Ensembl: ENSG00000115598
UniProt: Q9HB29
Structure
Position
2:102186973..102243086
AA seq 575 aa
MWSLLLCGLSIALPLSVTADGCKDIFMKNEILSASQPFAFNCTFPPITSGEVSVTWYKNS
SKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFEKHWCDT
SIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGERFTVLETRL
LVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIYPKNHSIEVQ
LGTTLIVDCNVTDTKDNTNLRCWRVNNTLVDDYYDESKRIREGVETHVSFREHNLYTVNI
TFLEVKMEDYGLPFMCHAGVSTAYIILQLPAPDFRAYLIGGLIALVAVAVSVVYIYNIFK
IDIVLWYRSAFHSTETIVDGKLYDAYVLYPKPHKESQRHAVDALVLNILPEVLERQCGYK
LFIFGRDEFPGQAVANVIDENVKLCRRLIVIVVPESLGFGLLKNLSEEQIAVYSALIQDG
MKVILIELEKIEDYTVMPESIQYIKQKHGAIRWHGDFTEQSQCMKTKFWKTVRYHMPPRR
CRPFPPVQLLQHTPCYRTAGPELGSRRKKCTLTTG
NT seq 1728 nt   +upstreamnt  +downstreamnt
atgtggtccttgctgctctgcgggttgtccatcgcccttccactgtctgtcacagcagat
ggatgcaaggacatttttatgaaaaatgagatactttcagcaagccagccttttgctttt
aattgtacattccctcccataacatctggggaagtcagtgtaacatggtataaaaattct
agcaaaatcccagtgtccaaaatcatacagtctagaattcaccaggacgagacttggatt
ttgtttctccccatggaatggggggactcaggagtctaccaatgtgttataaagggtaga
gacagctgtcatagaatacatgtaaacctaactgtttttgaaaaacattggtgtgacact
tccataggtggtttaccaaatttatcagatgagtacaagcaaatattacatcttggaaaa
gatgatagtctcacatgtcatctgcacttcccgaagagttgtgttttgggtccaataaag
tggtataaggactgtaacgagattaaaggggagcggttcactgttttggaaaccaggctt
ttggtgagcaatgtctcggcagaggacagagggaactacgcgtgtcaagccatactgaca
cactcagggaagcagtacgaggttttaaatggcatcactgtgagcattacagaaagagct
ggatatggaggaagtgtccctaaaatcatttatccaaaaaatcattcaattgaagtacag
cttggtaccactctgattgtggactgcaatgtaacagacaccaaggataatacaaatcta
cgatgctggagagtcaataacactttggtggatgattactatgatgaatccaaacgaatc
agagaaggggtggaaacccatgtctcttttcgggaacataatttgtacacagtaaacatc
accttcttggaagtgaaaatggaagattatggccttcctttcatgtgccacgctggagtg
tccacagcatacattatattacagctcccagctccggattttcgagcttacttgatagga
gggcttatcgccttggtggctgtggctgtgtctgttgtgtacatatacaacatttttaag
atcgacattgttctttggtatcgaagtgccttccattctacagagaccatagtagatggg
aagctgtatgacgcctatgtcttataccccaagccccacaaggaaagccagaggcatgcc
gtggatgccctggtgttgaatatcctgcccgaggtgttggagagacaatgtggatataag
ttgtttatattcggcagagatgaattccctggacaagccgtggccaatgtcatcgatgaa
aacgttaagctgtgcaggaggctgattgtcattgtggtccccgaatcgctgggctttggc
ctgttgaagaacctgtcagaagaacaaatcgcggtctacagtgccctgatccaggacggg
atgaaggttattctcattgagctggagaaaatcgaggactacacagtcatgccagagtca
attcagtacatcaaacagaagcatggtgccatccggtggcatggggacttcacggagcag
tcacagtgtatgaagaccaagttttggaagacagtgagataccacatgccgcccagaagg
tgtcggccgtttcctccggtccagctgctgcagcacacaccttgctaccgcaccgcaggc
ccagaactaggctcaagaagaaagaagtgtactctcacgactggctaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Drug (2)   
   KEGG DRUG (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (28)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (26)   
DNA sequence (42)   
   RefSeq(nuc) (32)   
   GenBank (5)   
   EMBL (5)   
3D Structure (1)   
   PDB (1)   
Protein domain (10)   
   Pfam (10)   
All databases (103)   

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