KEGG   Homo sapiens (human): 8916
Entry
8916              CDS       T01001                                 
Symbol
HERC3
Name
(RefSeq) HECT and RLD domain containing E3 ubiquitin protein ligase 3
  KO
K10614  E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04120  Ubiquitin mediated proteolysis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    8916 (HERC3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    8916 (HERC3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     8916 (HERC3)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  HECT type E3
   8916 (HERC3)
SSDB
Motif
Pfam: RCC1 HECT RCC1_2
Other DBs
NCBI-GeneID: 8916
NCBI-ProteinID: NP_055421
OMIM: 605200
HGNC: 4876
Ensembl: ENSG00000138641
UniProt: Q15034
Position
4:88523843..88708539
AA seq 1050 aa
MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL
NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT
TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS
PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR
TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA
CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK
YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA
NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE
QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP
SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV
NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ
AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS
IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT
CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE
LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI
SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP
TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN
LLDLPKYSSKEILSARLTQALDNYEGFSLA
NT seq 3153 nt   +upstreamnt  +downstreamnt
atgttatgttggggatattggtctctgggccaacctggtatcagcaccaacctgcaggga
attgtggctgagccccaggtgtgtgggttcatatctgacagaagtgtcaaggaagtggcc
tgtgggggaaaccactctgtgttcctgctggaagatggggaagtttacacatgtggtttg
aacaccaaggggcaactgggccatgagagggaaggaaacaagccagaacaaattggagct
ctggcagatcagcatatcattcatgtggcatgtggcgagtcccacagtctggccctcagt
gaccgaggccagctgttttcttggggtgcagggagtgatggtcagctaggactcatgact
actgaggattctgtggcagtgcccaggttaatacaaaagctgaaccagcaaacaatatta
caagtttcctgtggcaactggcattgcttggctcttgcggctgatggccagttcttcacc
tggggaaagaacagccatgggcagcttggcttagggaaggagttcccctcccaagccagc
ccacagagggtgaggtccctggaggggatcccactggctcaggtggctgccggaggggct
cacagctttgccctgtctctctcaggagctgtttttggctgggggatgaataatgccggg
cagctagggctcagtgatgaaaaagatcgagaatctccatgccatgtaaaactcttacgc
acgcaaaaagttgtctatattagttgtggagaagaacacacagcagttctcacaaagagt
ggaggtgtgtttacctttggcgctggttcctgtgggcaacttggacacgactccatgaat
gatgaggttaaccctagaagagttctagagctgatgggtagtgaagtaactcaaattgct
tgtggcagacaacataccctagccttcgtgccttcttctggactcatctatgcatttggt
tgtggagcaagaggtcaattaggaactgggcacacttgtaatgttaagtgcccatctcct
gtcaagggttactgggctgcccacagtggccagctttcagcccgagctgatcgctttaaa
tatcatatcgttaagcagatcttctctggaggagaccagacttttgtactttgctccaaa
tacgagaattattctcctgctgttgacttcaggactatgaaccaagcacattataccagt
ttaataaatgatgaaaccatagcagtttggagacaaaaactctcagaacacaacaatgca
aatacaatcaatggtgttgttcagatattatcttctgcagcctgttggaatggaagtttt
cttgaaaaaaaaattgatgaacattttaaaacgagtcccaaaatccctgggattgacctg
aactcaactagggtgttatttgagaagttaatgaactctcagcactccatgattctagaa
cagattttgaacagttttgaaagttgtctgattccccagttgtcaagctcaccaccagat
gttgaagccatgagaatctatttaatactacctgagtttcccctactccaggattccaag
tattatataacattgactattcccttggctatggccattcttcggctggatacaaacccc
agcaaagtactagataactggtggtctcaggtatgcccgaaatatttcatgaagctggta
aacctctataaaggtgcagtcctttatctactgaggggaagaaagacattcttaattccc
gtactgtttaacaattatatcacagcagctctcaaactcttggagaagttatataaggta
aatcttaaagtgaagcatgtggaatatgatacattttacattcctgagatttccaatctc
gtggacattcaggaagactacctcatgtggttcttgcatcaagcagggatgaaggctaga
ccatcaataatacaggatactgtaacactttgttcctaccctttcatctttgatgcccaa
gccaagaccaaaatgttacagacagatgctgaactacagatgcaggtggcagtcaatgga
gccaacctgcagaatgtcttcatgcttctcaccctggagcctctgctggccagaagcccc
ttcctggtccttcacgttcgcaggaacaaccttgttggagatgccctaagagagctgagc
attcattctgatattgatttgaaaaagcctctcaaagtaatctttgatggtgaagaagca
gtggatgccggtggtgttacaaaggaattttttcttttgctgttaaaagaacttttgaat
cccatctatggaatgtttacctactatcaagattcaaatctcttgtggttttcagacacg
tgttttgtagagcacaactggtttcacttgattggtataacctgtggactagctatctac
aactccactgtggtcgatctccacttcccattggctctctacaagaagttactcaatgta
aagcctggcttggaagacttaaaggagttgtcacccactgaaggaaggagtctccaagag
cttttagattaccccggggaggatgtggaggagactttctgcctcaacttcacgatctgc
cgagaaagctatggagtgattgaacagaagaagctgatacctgggggagataatgtaact
gtgtgcaaggataacaggcaggaatttgtggatgcttatgtgaattatgtcttccaaatc
tcagttcatgaatggtacacagccttctctagtggcttcctaaaggtgtgtggtggcaaa
gtacttgagctcttccagccttcagaactgagggctatgatggtggggaacagcaactac
aactgggaagaactggaagagactgccatctacaagggagattactcggccacacatccc
actgtaaaactattttgggaaacatttcatgagtttccattggaaaagaagaagaagttt
ctcttgttcctgacaggcagcgatcggattcccatctacggcatggccagtctgcagatt
gtcatccagtccacagccagcggggaggagtacttgccggtggcccacacttgctacaac
cttcttgacctccccaagtacagcagcaaagagattctgagtgcccggctgacccaggcc
cttgacaactatgaagggtttagtttggcctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (12)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (30)   
   RefSeq(nuc) (10)   
   GenBank (10)   
   EMBL (10)   
Protein domain (3)   
   Pfam (3)   
All databases (63)   

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