KEGG   Homo sapiens (human): 8985
Entry
8985              CDS       T01001                                 
Symbol
PLOD3, LH3
Name
(RefSeq) procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
  KO
K13646  lysyl hydroxylase/galactosyltransferase/glucosyltransferase [EC:1.14.11.4 2.4.1.50 2.4.1.66]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00310  Lysine degradation
hsa00514  Other types of O-glycan biosynthesis
hsa01100  Metabolic pathways
Disease
H01192  Lysyl hydroxylase 3 deficiency
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    8985 (PLOD3)
  09107 Glycan biosynthesis and metabolism
   00514 Other types of O-glycan biosynthesis
    8985 (PLOD3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:hsa01003]
    8985 (PLOD3)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.4  procollagen-lysine 5-dioxygenase
     8985 (PLOD3)
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.50  procollagen galactosyltransferase
     8985 (PLOD3)
    2.4.1.66  procollagen glucosyltransferase
     8985 (PLOD3)
Glycosyltransferases [BR:hsa01003]
 O-Glycan biosynthesis
  O-linked Gal type
   8985 (PLOD3)
SSDB
Motif
Pfam: 2OG-FeII_Oxy 2OG-FeII_Oxy_3
Other DBs
NCBI-GeneID: 8985
NCBI-ProteinID: NP_001075
OMIM: 603066
HGNC: 9083
Ensembl: ENSG00000106397
UniProt: O60568 Q9UG85
Structure
Position
7:complement(101205984..101217581)
AA seq 738 aa
MTSSGPGPRFLLLLPLLLPPAASASDRPRGRDPVNPEKLLVITVATAETEGYLRFLRSAE
FFNYTVRTLGLGEEWRGGDVARTVGGGQKVRWLKKEMEKYADREDMIIMFVDSYDVILAG
SPTELLKKFVQSGSRLLFSAESFCWPEWGLAEQYPEVGTGKRFLNSGGFIGFATTIHQIV
RQWKYKDDDDDQLFYTRLYLDPGLREKLSLNLDHKSRIFQNLNGALDEVVLKFDRNRVRI
RNVAYDTLPIVVHGNGPTKLQLNYLGNYVPNGWTPEGGCGFCNQDRRTLPGGQPPPRVFL
AVFVEQPTPFLPRFLQRLLLLDYPPDRVTLFLHNNEVFHEPHIADSWPQLQDHFSAVKLV
GPEEALSPGEARDMAMDLCRQDPECEFYFSLDADAVLTNLQTLRILIEENRKVIAPMLSR
HGKLWSNFWGALSPDEYYARSEDYVELVQRKRVGVWNVPYISQAYVIRGDTLRMELPQRD
VFSGSDTDPDMAFCKSFRDKGIFLHLSNQHEFGRLLATSRYDTEHLHPDLWQIFDNPVDW
KEQYIHENYSRALEGEGIVEQPCPDVYWFPLLSEQMCDELVAEMEHYGQWSGGRHEDSRL
AGGYENVPTVDIHMKQVGYEDQWLQLLRTYVGPMTESLFPGYHTKARAVMNFVVRYRPDE
QPSLRPHHDSSTFTLNVALNHKGLDYEGGGCRFLRYDCVISSPRKGWALLHPGRLTHYHE
GLPTTWGTRYIMVSFVDP
NT seq 2217 nt   +upstreamnt  +downstreamnt
atgacctcctcggggcctggaccccggttcctgctgctgctgccgctgctgctgccccct
gcggcctcagcctccgaccggccccggggccgagacccggtcaacccagagaagctgctg
gtgatcactgtggccacagctgaaaccgaggggtacctgcgtttcctgcgctctgcggag
ttcttcaactacactgtgcggaccctgggcctgggagaggagtggcgagggggtgatgtg
gctcgaacagttggtggaggacagaaggtccggtggttaaagaaggaaatggagaaatac
gctgaccgggaggatatgatcatcatgtttgtggatagctacgacgtgattctggccggc
agccccacagagctgctgaagaagttcgtccagagtggcagccgcctgctcttctctgca
gagagcttctgctggcccgagtgggggctggcggagcagtaccctgaggtgggcacgggg
aagcgcttcctcaattctggtggattcatcggttttgccaccaccatccaccaaatcgtg
cgccagtggaagtacaaggatgatgacgacgaccagctgttctacacacggctctacctg
gacccaggactgagggagaaactcagccttaatctggatcataagtctcggatctttcag
aacctcaacggggctttagatgaagtggttttaaagtttgatcggaaccgtgtgcgtatc
cggaacgtggcctacgacacgctccccattgtggtccatggaaacggtcccactaagctg
cagctcaactacctgggaaactacgtccccaatggctggactcctgagggaggctgtggc
ttctgcaaccaggaccggaggacactcccgggggggcagcctcccccccgggtgtttctg
gccgtgtttgtggaacagcctactccgtttctgccccgcttcctgcagcggctgctactc
ctggactatccccccgacagggtcacccttttcctgcacaacaacgaggtcttccatgaa
ccccacatcgctgactcctggccgcagctccaggaccacttctcagctgtgaagctcgtg
gggccggaggaggctctgagcccaggcgaggccagggacatggccatggacctgtgtcgg
caggaccccgagtgtgagttctacttcagcctggacgccgacgctgtcctcaccaacctg
cagaccctgcgtatcctcattgaggagaacaggaaggtgatcgcccccatgctgtcccgc
cacggcaagctgtggtccaacttctggggcgccctgagccccgatgagtactacgcccgc
tccgaggactacgtggagctggtgcagcggaagcgagtgggtgtgtggaatgtaccatac
atctcccaggcctatgtgatccggggtgataccctgcggatggagctgccccagagggat
gtgttctcgggcagtgacacagacccggacatggccttctgtaagagctttcgagacaag
ggcatcttcctccatctgagcaatcagcatgaatttggccggctcctggccacttccaga
tacgacacggagcacctgcaccccgacctctggcagatcttcgacaaccccgtcgactgg
aaggagcagtacatccacgagaactacagccgggccctggaaggggaaggaatcgtggag
cagccatgcccggacgtgtactggttcccactgctgtcagaacaaatgtgtgatgagctg
gtggcagagatggagcactacggccagtggtcaggcggccggcatgaggattcaaggctg
gctggaggctacgagaatgtgcccaccgtggacatccacatgaagcaggtggggtacgag
gaccagtggctgcagctgctgcggacgtatgtgggccccatgaccgagagcctgtttccc
ggttaccacaccaaggcgcgggcggtgatgaactttgtggttcgctaccggccagacgag
cagccgtctctgcggccacaccacgactcatccaccttcaccctcaacgttgccctcaac
cacaagggcctggactatgagggaggtggctgccgcttcctgcgctacgactgtgtgatc
tcctccccgaggaagggctgggcactcctgcaccccggccgcctcacccactaccacgag
gggctgccaacgacctggggcacacgctacatcatggtgtcctttgtcgacccctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (6)   
   KEGG ENZYME (3)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (24)   
   RefSeq(nuc) (2)   
   GenBank (11)   
   EMBL (11)   
3D Structure (14)   
   PDB (14)   
Protein domain (2)   
   Pfam (2)   
All databases (90)   

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