KEGG   Homo sapiens (human): 89941
Entry
89941             CDS       T01001                                 
Symbol
RHOT2, ARHT2, C16orf39, MIRO-2, MIRO2, RASL
Name
(RefSeq) ras homolog family member T2
  KO
K07871  mitochondrial Rho GTPase 2 [EC:3.6.5.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04137  Mitophagy - animal
Network
nt06536  Mitophagy
  Element
N01756  PINK-Parkin-independent ubiquitin-mediated mitophagy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    89941 (RHOT2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:hsa04031]
    89941 (RHOT2)
GTP-binding proteins [BR:hsa04031]
 Small (monomeric) G-proteins
  Rho Family
   Miro
    89941 (RHOT2)
SSDB
Motif
Pfam: EF_assoc_2 EF_assoc_1 Ras Roc EF-hand_7 AAA_16 Arf EF-hand_6 MMR_HSR1 EF-hand_1 SRPRB EF-hand_5
Other DBs
NCBI-GeneID: 89941
NCBI-ProteinID: NP_620124
OMIM: 613889
HGNC: 21169
Ensembl: ENSG00000140983
UniProt: Q8IXI1
Structure
Position
16:668083..674174
AA seq 618 aa
MRRDVRILLLGEAQVGKTSLILSLVGEEFPEEVPPRAEEITIPADVTPEKVPTHIVDYSE
AEQTDEELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKS
DLRSGSSMEAVLPIMSQFPEIETCVECSAKNLRNISELFYYAQKAVLHPTAPLYDPEAKQ
LRPACAQALTRIFRLSDQDLDQALSDEELNAFQKSCFGHPLAPQALEDVKTVVCRNVAGG
VREDRLTLDGFLFLNTLFIQRGRHETTWTILRRFGYSDALELTADYLSPLIHVPPGCSTE
LNHLGYQFVQRVFEKHDQDRDGALSPVELQSLFSVFPAAPWGPELPRTVRTEAGRLPLHG
YLCQWTLVTYLDVRSCLGHLGYLGYPTLCEQDQAHAITVTREKRLDQEKGQTQRSVLLCK
VVGARGVGKSAFLQAFLGRGLGHQDTREQPPGYAIDTVQVNGQEKYLILCEVGTDGLLAT
SLDATCDVACLMFDGSDPKSFAHCASVYKHHYMDGQTPCLFVSSKADLPEGVAVSGPSPA
EFCRKHRLPAPVPFSCAGPAEPSTTIFTQLATMAAFPHLVHAELHPSSFWLRGLLGVVGA
AVAAVLSFSLYRVLVKSQ
NT seq 1857 nt   +upstreamnt  +downstreamnt
atgaggcgggacgtgcgcatcctgttactgggcgaggcccaggtggggaagacgtcgctg
atcctgtccctggtgggcgaggagttccccgaggaggtccctccccgcgcggaggagatc
accatccccgcggacgtcaccccggagaaggtgcccacccacatcgtggactactcagaa
gccgagcagacggacgaggagctgcgggaggagatccacaaggcaaacgtggtgtgtgtg
gtgtatgacgtctctgaggaggccaccattgagaagattcgaactaagtggatcccactg
gtgaatggggggaccacgcaggggcccagggtgcccatcatcctagtgggcaacaagtca
gacctgcggtcggggagctccatggaggccgtgctccccatcatgagccagtttcccgag
attgagacctgcgtggagtgttcggccaagaacctgaggaacatctcagagctgttctac
tacgcccagaaggccgtcctgcatcccacagcccccctctatgaccctgaggccaagcag
ttgaggcccgcgtgcgcccaggcgctgacgcgcatcttcaggctctcagatcaggacctg
gaccaggcgctcagtgacgaagagctcaacgctttccagaaatcctgctttgggcacccc
ctggccccgcaggccctggaggacgtgaagacggtggtgtgcaggaacgtggcgggcggc
gtgcgggaggaccggctgaccctggatggtttcctcttcctgaacacgctcttcatccag
cgcggccggcacgagaccacctggaccatcctgcggcgcttcggctacagcgatgccctg
gagctgactgcggactatctctcccctctgatccacgtgccccccggctgcagcacggag
ctcaaccaccttggctaccagtttgtgcagagagtgtttgagaagcacgaccaggaccgc
gacggcgccctctcgcccgtggagctgcaaagccttttcagtgtgttcccagcagcgccc
tggggccccgagctcccacgcacagtccgcacagaggccggccggttgcccctgcacgga
tacctctgccagtggaccctggtgacctacctggacgtccggagctgccttggacaccta
ggctacctgggctaccccaccctctgtgagcaggaccaggcccatgccatcacagtcact
cgtgagaagaggctggaccaggagaagggacagacgcagcggagcgtcctcctgtgcaag
gtggtaggggcccgtggagtgggcaagtctgccttcctgcaggcctttctcggccgcggc
ctggggcaccaggacacgagggagcagcctcccggctacgccatcgacacggtgcaggtc
aatggacaggagaagtacttgatcctctgtgaggtgggcacagatggtctgctggccaca
tcgctggacgccacctgtgacgttgcctgcttgatgtttgatggcagtgacccaaagtcc
tttgcacattgtgccagcgtctacaagcaccattacatggacgggcagaccccctgcctc
tttgtctcctccaaggccgacctgcccgaaggtgtcgcggtgtctggcccatcaccggcc
gagttttgccgcaagcaccggctacccgctcccgtgccgttctcctgtgctggcccagcc
gagcccagcaccaccatcttcacccagctcgccaccatggccgccttcccacatttggtc
cacgcagagctgcatccctcttccttctggctccgggggctgctgggggttgtcggggcc
gccgtggccgcagtcctcagcttctcactctacagggtcctggtgaagagccagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (41)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (39)   
DNA sequence (61)   
   RefSeq(nuc) (43)   
   GenBank (9)   
   EMBL (9)   
3D Structure (1)   
   PDB (1)   
Protein domain (12)   
   Pfam (12)   
All databases (135)   

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