KEGG   Homo sapiens (human): 9
Entry
9                 CDS       T01001                                 
Symbol
NAT1, AAC1, MNAT, NAT-1, NATI
Name
(RefSeq) N-acetyltransferase 1
  KO
K00622  arylamine N-acetyltransferase [EC:2.3.1.5]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00232  Caffeine metabolism
hsa00983  Drug metabolism - other enzymes
hsa01100  Metabolic pathways
hsa05204  Chemical carcinogenesis - DNA adducts
Network
nt06250  DNA adduct formation (cancer)
  Element
N01369  4-ABP to DNA adducts
N01372  IQ to DNA adducts
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00232 Caffeine metabolism
    9 (NAT1)
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    9 (NAT1)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    9 (NAT1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.5  arylamine N-acetyltransferase
     9 (NAT1)
SSDB
Motif
Pfam: Acetyltransf_2
Other DBs
NCBI-GeneID: 9
NCBI-ProteinID: NP_000653
OMIM: 108345
HGNC: 7645
Ensembl: ENSG00000171428
UniProt: P18440
Structure
Position
8:18170467..18223689
AA seq 290 aa
MDIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVV
RRNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYI
VDAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDL
LEDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLT
HRRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISLQRKLVPKHGDRFFTI
NT seq 873 nt   +upstreamnt  +downstreamnt
atggacattgaagcatatcttgaaagaattggctataagaagtctaggaacaaattggac
ttggaaacattaactgacattcttcaacaccagatccgagctgttccctttgagaacctt
aacatccattgtggggatgccatggacttaggcttagaggccatttttgatcaagttgtg
agaagaaatcggggtggatggtgtctccaggtcaatcatcttctgtactgggctctgacc
actattggttttgagaccacgatgttgggagggtatgtttacagcactccagccaaaaaa
tacagcactggcatgattcaccttctcctgcaggtgaccattgatggcaggaactacatt
gtcgatgctgggtttggacgctcataccagatgtggcagcctctggagttaatttctggg
aaggatcagcctcaggtgccttgtgtcttccgtttgacggaagagaatggattctggtat
ctagaccaaatcagaagggaacagtacattccaaatgaagaatttcttcattctgatctc
ctagaagacagcaaataccgaaaaatctactcctttactcttaagcctcgaacaattgaa
gattttgagtctatgaatacatacctgcagacatctccatcatctgtgtttactagtaaa
tcattttgttccttgcagaccccagatggggttcactgtttggtgggcttcaccctcacc
cataggagattcaattataaggacaatacagatctaatagagttcaagactctgagtgag
gaagaaatagaaaaagtgctgaaaaatatatttaatatttccttgcagagaaagcttgtg
cccaaacatggtgatagattttttactatttag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Network (3)   
   KEGG NETWORK (3)   
Disease (1)   
   OMIM (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (6)   
   KEGG ENZYME (1)   
   KEGG REACTION (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (22)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (20)   
DNA sequence (76)   
   RefSeq(nuc) (20)   
   GenBank (28)   
   EMBL (28)   
3D Structure (2)   
   PDB (2)   
Protein domain (1)   
   Pfam (1)   
All databases (141)   

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