KEGG   Homo sapiens (human): 90865
Entry
90865             CDS       T01001                                 
Symbol
IL33, C9orf26, DVS27, IL1F11, NF-HEV, NFEHEV
Name
(RefSeq) interleukin 33
  KO
K12967  interleukin 33
Organism
hsa  Homo sapiens (human)
Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04217  Necroptosis
hsa04623  Cytosolic DNA-sensing pathway
hsa05164  Influenza A
Network
nt06170  Influenza A virus (IAV)
nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06182  Shigella
nt06183  Yersinia
nt06521  NLR signaling
  Element
N00742  NLRP3 inflammasome signaling pathway
Drug target
Etokimab: D11449
Itepekimab: D11999
Tozorakimab: D12375
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    90865 (IL33)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    90865 (IL33)
 09150 Organismal Systems
  09151 Immune system
   04623 Cytosolic DNA-sensing pathway
    90865 (IL33)
 09160 Human Diseases
  09172 Infectious disease: viral
   05164 Influenza A
    90865 (IL33)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:hsa04052]
    90865 (IL33)
Cytokines and neuropeptides [BR:hsa04052]
 Cytokines
  Interleukins
   90865 (IL33)
SSDB
Motif
Pfam: IL33 AbfB
Other DBs
NCBI-GeneID: 90865
NCBI-ProteinID: NP_001300973
OMIM: 608678
HGNC: 16028
Ensembl: ENSG00000137033
UniProt: O95760
Structure
Position
9:6215149..6257983
AA seq 270 aa
MKPKMKYSTNKISTAKWKNTASKALCFKLGKSQQKAKEVCPMYFMKLRSGLMIKKEACYF
RRETTKRPSLKTGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSSITGISPIT
EYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGK
MLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFI
GVKDNHLALIKVDSSENLCTENILFKLSET
NT seq 813 nt   +upstreamnt  +downstreamnt
atgaagcctaaaatgaagtattcaaccaacaaaatttccacagcaaagtggaagaacaca
gcaagcaaagccttgtgtttcaagctgggaaaatcccaacagaaggccaaagaagtttgc
cccatgtactttatgaagctccgctctggccttatgataaaaaaggaggcctgttacttt
aggagagaaaccaccaaaaggccttcactgaaaacaggtagaaagcacaaaagacatctg
gtactcgctgcctgtcaacagcagtctactgtggagtgctttgcctttggtatatcaggg
gtccagaaatatactagagcacttcatgattcaagtatcacaggaatttcacctattaca
gagtatcttgcttctctaagcacatacaatgatcaatccattacttttgctttggaggat
gaaagttatgagatatatgttgaagacttgaaaaaagatgaaaagaaagataaggtgtta
ctgagttactatgagtctcaacacccctcaaatgaatcaggtgacggtgttgatggtaag
atgttaatggtaaccctgagtcctacaaaagacttctggttgcatgccaacaacaaggaa
cactctgtggagctccataagtgtgaaaaaccactgccagaccaggccttctttgtcctt
cataatatgcactccaactgtgtttcatttgaatgcaagactgatcctggagtgtttata
ggtgtaaaggataatcatcttgctctgattaaagtagactcttctgagaatttgtgtact
gaaaatatcttgtttaagctctctgaaacttag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Network (7)   
   KEGG NETWORK (7)   
Disease (1)   
   OMIM (1)   
Drug (3)   
   KEGG DRUG (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (23)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (21)   
DNA sequence (59)   
   RefSeq(nuc) (21)   
   GenBank (19)   
   EMBL (19)   
3D Structure (2)   
   PDB (2)   
Protein domain (2)   
   Pfam (2)   
All databases (117)   

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