KEGG   Homo sapiens (human): 90957
Entry
90957             CDS       T01001                                 
Symbol
DHX57, DDX57
Name
(RefSeq) DExH-box helicase 57
  KO
K13026  ATP-dependent RNA helicase DHX57 [EC:5.6.2.6]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09190 Not Included in Pathway or Brite
  09191 Unclassified: metabolism
   99980 Enzymes with EC numbers
    90957 (DHX57)
Enzymes [BR:hsa01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.6  RNA 3'-5' helicase
     90957 (DHX57)
SSDB
Motif
Pfam: OB_NTP_bind RWD Helicase_C DEAD HA2_C zf-CCCH_4 HA2_N zf-CCCH Torus zf_CCCH_4 zf-CCCH_2 nSTAND3 AAA_22 AAA_19 NB-ARC AAA_14 Adeno_IVa2 T2SSE Viral_helicase1
Other DBs
NCBI-GeneID: 90957
NCBI-ProteinID: NP_945314
HGNC: 20086
Ensembl: ENSG00000163214
UniProt: Q6P158
Position
2:complement(38797729..38875934)
AA seq 1386 aa
MSSSVRRKGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASSRIWDD
GDDFCIFSESRRPSRPSNSNISKGESRPKWKPKAKVPLQTLHMTSENQEKVKALLRDLQE
QDADAGSERGLSGEEEDDEPDCCNDERYWPAGQEPSLVPDLDPLEYAGLASVEPYVPEFT
VSPFAVQKLSRYGFNTERCQAVLRMCDGDVGASLEHLLTQCFSETFGERMKISEAVNQIS
LDECMEQRQEEAFALKSICGEKFIERIQNRVWTIGLELEYLTSRFRKSKPKESTKNVQEN
SLEICKFYLKGNCKFGSKCRFKHEVPPNQIVGRIERSVDDSHLNAIEDASFLYELEIRFS
KDHKYPYQAPLVAFYSTNENLPLACRLHISEFLYDKALTFAETSEPVVYSLITLLEEESE
IVKLLTNTHHKYSDPPVNFLPVPSRTRINNPACHKTVIPNNSFVSNQIPEVEKASESEES
DEDDGPAPVIVENESYVNLKKKISKRYDWQAKSVHAENGKICKQFRMKQASRQFQSILQE
RQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVANIICTQ
PRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDTALQ
GVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLNAELFSDYFNSCPVITI
PGRTFPVDQFFLEDAIAVTRYVLQDGSPYMRSMKQISKEKLKARRNRTAFEEVEEDLRLS
LHLQDQDSVKDAVPDQQLDFKQLLARYKGVSKSVIKTMSIMDFEKVNLELIEALLEWIVD
GKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHSSLSSEEQQAVFV
KPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESLEDTFVSQANALQ
RKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSAHNLQSV
FSRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLGYHLASLPVDVRIGKLMLFGSIFRC
LDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFAFANSDYLALLQAYKGWQLSTKEGVR
ASYNYCRQNFLSGRVLQEMASLKRQFTELLSDIGFAREGLRAREIEKRAQGGDGVLDATG
EEANSNAENPKLISAMLCAALYPNVVQVKSPEGKFQKTSTGAVRMQPKSAELKFVTKNDG
YVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVFIRDCSMVSVYPLVLFGGGQVNVQLQRG
EFVVSLDDGWIRFVAASHQVAELVKELRCELDQLLQDKIKNPSIDLCTCPRGSRIISTIV
KLVTTQ
NT seq 4161 nt   +upstreamnt  +downstreamnt
atgagttcttcagtaagaagaaaaggcaagccaggcaaaggaggtggaaaagggtcttct
agaggaggaagaggaggcaggagtcacgccagtaaatctcatgggagtggtggcggtggc
ggtggtggtggtggtggaggtggcggcaacagaaaggcctccagtagaatatgggatgat
ggagatgacttttgtatcttcagtgaatcaaggcgcccttccagacctagcaacagtaac
ataagcaaaggagagtcacgcccaaaatggaaacccaaagccaaagtaccccttcagact
ctacatatgacttctgagaatcaagagaaagtgaaagctcttctccgagacctgcaagaa
caagatgctgatgctggatctgaaagaggcctttctggggaggaggaagatgatgagcct
gattgctgtaacgatgagcggtactggccagctggacaggaaccttccctcgttcccgac
ttggatcctttggaatatgctggcttagcctcagtggagccttatgttccagaatttaca
gtctccccatttgcagtgcaaaaactttccaggtatggtttcaatactgaacgctgtcaa
gcggtcctgaggatgtgtgatggagatgtgggagcatcactagagcatctccttacccag
tgtttttcagagacatttggagagaggatgaagatctctgaggcagtcaaccagataagc
ttggatgagtgtatggaacagcgacaggaagaggcatttgctctcaagtccatctgtgga
gaaaaatttatagaaagaattcagaacagagtctggaccattgggttagaactggagtat
ctgacaagtagattccgcaaatccaagccaaaagaaagtaccaaaaatgtacaagagaat
tcacttgaaatctgtaaattttacctcaaaggaaattgtaaatttggatcaaaatgcaga
ttcaaacatgaagtgcccccaaatcaaattgttggaagaatagaaagaagtgtagatgat
tctcatcttaatgctattgaagatgcatcttttttatatgaacttgaaattcgattttct
aaagaccacaaatatccctaccaagctccgctcgtggcattttattccaccaatgagaac
ctacctctggcttgtcgtttacatatttctgagtttctttatgacaaggccttgacattt
gcggaaacttcggaacctgtcgtatattctttgataacccttttagaggaagagtcggaa
atagtcaagttactaacgaatacccaccacaagtatagtgaccctcctgtgaactttctg
ccagtaccctctaggaccagaataaataatcctgcctgtcataaaacagtgattccaaat
aattcttttgtttctaatcaaattccagaagttgaaaaagcatcagaatctgaggagtca
gatgaggatgacggtcctgcacctgttatagtagagaatgaaagctatgtgaaccttaag
aaaaagatttccaaaagatatgactggcaggcaaagtcagtacatgctgaaaatggtaaa
atctgcaagcagttccgaatgaaacaggcttccagacagttccagtccattctgcaagag
aggcaatcactccctgcttgggaagaaagagaaaccattcttaacttattgcgtaagcac
caggtggttgtcataagtggtatgactggatgtgggaaaaccacacaaattccgcagttt
attctggatgattctctgaatggaccacctgagaaggtagccaacatcatctgtacccaa
ccccgacgaatctctgcaatctctgttgctgaacgcgttgctaaagaaagagcagagagg
gtgggtctgaccgtgggataccagattcggttagaaagtgtcaagtcctcagccaccaga
ctgttatactgcaccacgggagtgctgctgagaaggctagaaggagatacagctctacaa
ggagtttcccatatcattgttgatgaagttcatgagaggacagaagaaagtgacttcttg
ctgctagttttgaaggacattgtatcgcagaggccaggtcttcaagttattttaatgagt
gcaactctaaacgctgagcttttttcagactattttaattcctgccccgttattactata
ccaggtcgtacatttcctgttgatcaattttttttggaagatgcaattgctgtgacaagg
tatgtattacaggatgggagcccatatatgcggtccatgaaacagatttcaaaggaaaag
cttaaagcaaggcggaacagaactgcatttgaagaagtggaagaagacctaaggctctcc
cttcacctccaggatcaggattctgtcaaagatgcagtgccagatcaacagttagatttt
aagcagctcctggcccgctataaaggggttagcaagtcagtcatcaaaacaatgtccatc
atggattttgaaaaggtgaatcttgaattaatagaggccttattagagtggattgtggat
ggaaagcactcctaccctccaggtgctatacttgtatttttaccaggactagcagaaatc
aaaatgctttatgaacagctacagtctaattctcttttcaacaacagacgtagtaatcga
tgtgttattcacccacttcattcatctttatccagtgaagagcagcaggctgtgtttgta
aaacctcctgcaggagtaactaagattataatttccaccaacattgctgagacatccata
accatcgatgatgttgtctatgttatcgattctgggaaaatgaaagaaaagagatatgat
gccagcaaagggatggaaagtctagaggacacctttgtatctcaagctaatgctctacaa
aggaaaggccgagcaggccgtgttgcatctggggtctgcttccatttattcactagccat
cactacaatcaccagcttttaaaacaacagctaccagaaatacaaagagtgccattggaa
cagctgtgtctaagaattaaaattttagagatgtttagtgctcataatctccagtctgtg
ttctctcggctcattgaacctccacacaccgattctcttcgtgcctcaaaaatacgatta
cgagacttaggagcattaactccagatgaaagattgacccctcttgggtatcatttggcc
tctctgcccgtggatgtgagaattggcaaactaatgttgtttgggtctatcttccgctgt
ttggatcctgctctcaccattgctgccagtttggcttttaagtctccgtttgtatctccc
tgggataaaaaagaagaagctaaccagaaaaagctggaatttgcattcgcaaacagtgat
tatctggcccttctacaagcgtataagggatggcagctaagtacaaaagaaggcgtgcgt
gcaagttataattactgcagacaaaacttcttgtctggaagagttctgcaggaaatggcc
agcctcaaacgacaattcacggaactgttatcggatatagggtttgcaagggaagggctc
agagcaagggaaattgagaaaagggcccaaggaggagatggtgtcttagatgccacagga
gaagaggcaaactcaaatgctgagaaccccaagctgatatcagcaatgctgtgtgctgct
ttgtatccaaatgtagtgcaggtgaaaagcccagaaggaaaatttcagaagaccagtact
ggagctgtcagaatgcaaccaaaatcagctgagttgaagtttgtcaccaagaacgatgga
tatgtacacattcacccttcatcagtgaactatcaggtgagacactttgacagcccctac
ctgttgtaccacgagaagataaaaactagtcgagtattcatccgagactgcagcatggtg
tctgtgtacccgctggtcttgtttggaggaggccaagtgaatgtgcagcttcaaagagga
gagttcgttgtctccctggatgatggttggatccgttttgtagctgcttcccatcaggtg
gctgaactggtaaaggagcttcgttgcgaacttgatcagcttctccaggataaaattaaa
aacccaagcattgatctgtgtacgtgtcctcgaggatcccggatcatcagcacaattgtg
aaacttgtcaccacacaataa

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Ontology (1)   
   KEGG BRITE (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (32)   
   KEGG ORTHOLOGY (1)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (16)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (14)   
DNA sequence (54)   
   RefSeq(nuc) (16)   
   GenBank (19)   
   EMBL (19)   
Protein domain (19)   
   Pfam (19)   
All databases (124)   

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