KEGG   Homo sapiens (human): 9146
Entry
9146              CDS       T01001                                 
Symbol
HGS, HRS
Name
(RefSeq) hepatocyte growth factor-regulated tyrosine kinase substrate
  KO
K12182  hepatocyte growth factor-regulated tyrosine kinase substrate
Organism
hsa  Homo sapiens (human)
Pathway
hsa03250  Viral life cycle - HIV-1
hsa04144  Endocytosis
hsa04145  Phagosome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03250 Viral life cycle - HIV-1
    9146 (HGS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    9146 (HGS)
   04145 Phagosome
    9146 (HGS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    9146 (HGS)
Membrane trafficking [BR:hsa04131]
 Endosome - Lysosome transport
  Endosomal sorting complexes required for transport (ESCRT)
   ESCRT-0 complex
    9146 (HGS)
SSDB
Motif
Pfam: VHS Hrs_helical FYVE FYVE_2 FYVE_CARP1-2 Maestro_HEAT UIM DUF1071
Other DBs
NCBI-GeneID: 9146
NCBI-ProteinID: NP_004703
OMIM: 604375
HGNC: 4897
Ensembl: ENSG00000185359
UniProt: O14964 A0A0S2Z4R4
Structure
Position
17:81684011..81702121
AA seq 777 aa
MGRGSGTFERLLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHV
ALYALEVMESVVKNCGQTVHDEVANKQTMEELKDLLKRQVEVNVRNKILYLIQAWAHAFR
NEPKYKVVQDTYQIMKVEGHVFPEFKESDAMFAAERAPDWVDAEECHRCRVQFGVMTRKH
HCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLNRKAEGKATSTTELPPEYLTS
PLSQQSQLPPKRDETALQEEEELQLALALSQSEAEEKERLRQKSTYTSYPKAEPMPSASS
APPASSLYSSPVNSSAPLAEDIDPELARYLNRNYWEKKQEEARKSPTPSAPVPLTEPAAQ
PGEGHAAPTNVVENPLPETDSQPIPPSGGPFSEPQFHNGESEESHEQFLKALQNAVTTFV
NRMKSNHMRGRSITNDSAVLSLFQSINGMHPQLLELLNQLDERRLYYEGLQDKLAQIRDA
RGALSALREEHREKLRRAAEEAERQRQIQLAQKLEIMRQKKQEYLEVQRQLAIQRLQEQE
KERQMRLEQQKQTVQMRAQMPAFPLPYAQLQAMPAAGGVLYQPSGPASFPSTFSPAGSVE
GSPMHGVYMSQPAPAAGPYPSMPSTAADPSMVSAYMYPAGATGAQAAPQAQAGPTASPAY
SSYQPTPTAGYQNVASQAPQSLPAISQPPQSSTMGYMGSQSVSMGYQPYNMQNLMTTLPS
QDASLPPQQPYIAGQQPMYQQMAPSGGPPQQQPPVAQQPQAQGPPAQGSEAQLISFD
NT seq 2334 nt   +upstreamnt  +downstreamnt
atggggcgaggcagcggcaccttcgagcgtctcctagacaaggcgaccagccagctcctg
ttggagacagattgggagtccattttgcagatctgcgacctgatccgccaaggggacaca
caagcaaaatatgctgtgaattccatcaagaagaaagtcaacgacaagaacccacacgtc
gccttgtatgccctggaggtcatggaatctgtggtaaagaactgtggccagacagttcat
gatgaggtggccaacaagcagaccatggaggagctgaaggacctgctgaagagacaagtg
gaggtaaacgtccgtaacaagatcctgtacctgatccaggcctgggcgcatgccttccgg
aacgagcccaagtacaaggtggtccaggacacctaccagatcatgaaggtggaggggcac
gtctttccagaattcaaagagagcgatgccatgtttgctgccgagagagccccagactgg
gtggacgctgaggaatgccaccgctgcagggtgcagttcggggtgatgacccgtaagcac
cactgccgggcgtgtgggcagatattctgtggaaagtgttcttccaagtactccaccatc
cccaagtttggcatcgagaaggaggtgcgcgtgtgtgagccctgctacgagcagctgaac
aggaaagcggagggaaaggccacttccaccactgagctgccccccgagtacctgaccagc
cccctgtctcagcagtcccagctgccccccaagagggacgagacggccctgcaggaggag
gaggagctgcagctggccctggcgctgtcacagtcagaggcggaggagaaggagaggctg
agacagaagtccacgtacacttcgtaccccaaggcggagcccatgccctcggcctcctca
gcgccccccgccagcagcctgtactcttcacctgtgaactcgtcggcgcctctggctgag
gacatcgaccctgagctcgcacggtatctcaaccggaactactgggagaagaagcaggag
gaggctcgcaagagccccacgccatctgcgcccgtgcccctgacggagccggctgcacag
cctggggaagggcacgcagcccccaccaacgtggtggagaaccccctcccggagacagac
tctcagcccattcctccctctggtggcccctttagtgagccacagttccacaatggcgag
tctgaggagagccacgagcagttcctgaaggcgctgcagaacgccgtcaccaccttcgtg
aaccgcatgaagagtaaccacatgcggggccgcagcatcaccaatgactcggccgtgctc
tcactcttccagtccatcaacggcatgcacccgcagctgctggagctgctcaaccagctg
gacgagcgcaggctgtactatgaggggctgcaggacaagctggcacagatccgcgatgcc
cggggggcgctgagtgccctgcgcgaagagcaccgggagaagcttcgccgggcagccgag
gaggcagagcgccagcgccagatccagctggcccagaagctggagataatgcggcagaag
aagcaggagtacctggaggtgcagaggcagctggccatccagcgcctgcaggagcaggag
aaggagcggcagatgcggctggagcagcagaagcagacggtccagatgcgcgcgcagatg
cccgccttccccctgccctacgcccagctccaggccatgcccgcagccggaggtgtgctc
taccagccctcgggaccagccagcttccccagcaccttcagccctgccggctcggtggag
ggctccccaatgcacggcgtgtacatgagccagccggcccctgccgctggcccctacccc
agcatgcccagcactgcggctgatcccagcatggtgagtgcctacatgtacccagcaggg
gccactggggcgcaggcggccccccaggcccaggccggacccaccgccagccccgcttac
tcatcctaccagcctactcccacagcgggctaccagaacgtggcctcccaggccccacag
agcctcccggccatctctcagcctccgcagtccagcaccatgggctacatggggagccag
tcagtctccatgggctaccagccttacaacatgcagaatctcatgaccaccctcccaagc
caggatgcgtctctgccaccccagcagccctacatcgcggggcagcagcccatgtaccag
cagatggcaccctctggcggtcccccccagcagcagccccccgtggcccagcaaccgcag
gcacaggggccgccggcacagggcagcgaggcccagctcatttcattcgactga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (27)   
   RefSeq(nuc) (1)   
   GenBank (13)   
   EMBL (13)   
3D Structure (5)   
   PDB (5)   
Protein domain (8)   
   Pfam (8)   
All databases (75)   

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