KEGG   Homo sapiens (human): 9156
Entry
9156              CDS       T01001                                 
Symbol
EXO1, HEX1, hExoI
Name
(RefSeq) exonuclease 1
  KO
K10746  exonuclease 1 [EC:3.1.-.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03430  Mismatch repair
Network
nt06503  Mismatch repair
  Element
N01432  Mismatch repair
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03430 Mismatch repair
    9156 (EXO1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:hsa03032]
    9156 (EXO1)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    9156 (EXO1)
DNA replication proteins [BR:hsa03032]
 Eukaryotic type
  DNA Replication Elongation Factors
   Other elongation factors
    9156 (EXO1)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   MMR (mismatch excision repair)
    Other MMR factors
     9156 (EXO1)
SSDB
Motif
Pfam: XPG_N XPG_I XPG_I_2
Other DBs
NCBI-GeneID: 9156
NCBI-ProteinID: NP_006018
OMIM: 606063
HGNC: 3511
Ensembl: ENSG00000174371
UniProt: Q9UQ84
Structure
Position
1:241847986..241889939
AA seq 846 aa
MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
DDESHPLREEACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
KLRLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
QRAIFQ
NT seq 2541 nt   +upstreamnt  +downstreamnt
atggggatacagggattgctacaatttatcaaagaagcttcagaacccatccatgtgagg
aagtataaagggcaggtagtagctgtggatacatattgctggcttcacaaaggagctatt
gcttgtgctgaaaaactagccaaaggtgaacctactgataggtatgtaggattttgtatg
aaatttgtaaatatgttactatctcatgggatcaagcctattctcgtatttgatggatgt
actttaccttctaaaaaggaagtagagagatctagaagagaaagacgacaagccaatctt
cttaagggaaagcaacttcttcgtgaggggaaagtctcggaagctcgagagtgtttcacc
cggtctatcaatatcacacatgccatggcccacaaagtaattaaagctgcccggtctcag
ggggtagattgcctcgtggctccctatgaagctgatgcgcagttggcctatcttaacaaa
gcgggaattgtgcaagccataattacagaggactcggatctcctagcttttggctgtaaa
aaggtaattttaaagatggaccagtttggaaatggacttgaaattgatcaagctcggcta
ggaatgtgcagacagcttggggatgtattcacggaagagaagtttcgttacatgtgtatt
ctttcaggttgtgactacctgtcatcactgcgtgggattggattagcaaaggcatgcaaa
gtcctaagactagccaataatccagatatagtaaaggttatcaagaaaattggacattat
ctcaagatgaatatcacggtaccagaggattacatcaacgggtttattcgggccaacaat
accttcctctatcagctagtttttgatcccatcaaaaggaaacttattcctctgaacgcc
tatgaagatgatgttgatcctgaaacactaagctacgctgggcaatatgttgatgattcc
atagctcttcaaatagcacttggaaataaagatataaatacttttgaacagatcgatgac
tacaatccagacactgctatgcctgcccattcaagaagtcatagttgggatgacaaaaca
tgtcaaaagtcagctaatgttagcagcatttggcataggaattactctcccagaccagag
tcgggtactgtttcagatgccccacaattgaaggaaaatccaagtactgtgggagtggaa
cgagtgattagtactaaagggttaaatctcccaaggaaatcatccattgtgaaaagacca
agaagtgcagagctgtcagaagatgacctgttgagtcagtattctctttcatttacgaag
aagaccaagaaaaatagctctgaaggcaataaatcattgagcttttctgaagtgtttgtg
cctgacctggtaaatggacctactaacaaaaagagtgtaagcactccacctaggacgaga
aataaatttgcaacatttttacaaaggaaaaatgaagaaagtggtgcagttgtggttcca
gggaccagaagcaggtttttttgcagttcagattctactgactgtgtatcaaacaaagtg
agcatccagcctctggatgaaactgctgtcacagataaagagaacaatctgcatgaatca
gagtatggagaccaagaaggcaagagactggttgacacagatgtagcacgtaattcaagt
gatgacattccgaataatcatattccaggtgatcatattccagacaaggcaacagtgttt
acagatgaagagtcctactcttttgagagcagcaaatttacaaggaccatttcaccaccc
actttgggaacactaagaagttgttttagttggtctggaggtcttggagatttttcaaga
acgccgagcccctctccaagcacagcattgcagcagttccgaagaaagagcgattccccc
acctctttgcctgagaataatatgtctgatgtgtcgcagttaaagagcgaggagtccagt
gacgatgagtctcatcccttacgagaagaggcatgttcttcacagtcccaggaaagtgga
gaattctcactgcagagttcaaatgcatcaaagctttctcagtgctctagtaaggactct
gattcagaggaatctgattgcaatattaagttacttgacagtcaaagtgaccagacctcc
aagctacgtttatctcatttctcaaaaaaagacacacctctaaggaacaaggttcctggg
ctatataagtccagttctgcagactctctttctacaaccaagatcaaacctctaggacct
gccagagccagtgggctgagcaagaagccggcaagcatccagaagagaaagcatcataat
gccgagaacaagccggggttacagatcaaactcaatgagctctggaaaaactttggattt
aaaaaagattctgaaaagcttcctccttgtaagaaacccctgtccccagtcagagataac
atccaactaactccagaagcggaagaggatatatttaacaaacctgaatgtggccgtgtt
caaagagcaatattccagtaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (44)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (42)   
DNA sequence (70)   
   RefSeq(nuc) (42)   
   GenBank (14)   
   EMBL (14)   
3D Structure (23)   
   PDB (23)   
Protein domain (3)   
   Pfam (3)   
All databases (165)   

Download RDF
DBGET integrated database retrieval system