KEGG   Homo sapiens (human): 9180
Entry
9180              CDS       T01001                                 
Symbol
OSMR, IL-31R-beta, IL-31RB, OSMRB, OSMRbeta, PLCA1
Name
(RefSeq) oncostatin M receptor
  KO
K05057  oncostatin M receptor
Organism
hsa  Homo sapiens (human)
Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04151  PI3K-Akt signaling pathway
hsa04630  JAK-STAT signaling pathway
Network
nt06518  JAK-STAT signaling
  Element
N01556  IL6 family to Jak-STAT signaling pathway
Disease
H01217  Primary localized cutaneous amyloidosis
Drug target
Vixarelimab: D11800
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    9180 (OSMR)
   04151 PI3K-Akt signaling pathway
    9180 (OSMR)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    9180 (OSMR)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:hsa04050]
    9180 (OSMR)
Cytokine receptors [BR:hsa04050]
 Interleukin receptor families
  IL6/12 receptor family
   9180 (OSMR)
SSDB
Motif
Pfam: fn3 LIFR_D2 LIF-R_Ig-like Pur_ac_phosph_N EpoR_lig-bind
Other DBs
NCBI-GeneID: 9180
NCBI-ProteinID: NP_001310434
OMIM: 601743
HGNC: 8507
Ensembl: ENSG00000145623
UniProt: Q99650
Position
5:38846012..38945579
AA seq 979 aa
MALFAVFQTTFFLTLLSLRTYQSEVLAERLPLTPVSLKVSTNSTRQSLHLQWTVHNLPYH
QELKMVFQIQISRIETSNVIWVGNYSTTVKWNQVLHWSWESELPLECATHFVRIKSLVDD
AKFPEPNFWSNWSSWEEVSVQDSTGQDILFVFPKDKLVEEGTNVTICYVSRNIQNNVSCY
LEGKQIHGEQLDPHVTAFNLNSVPFIRNKGTNIYCEASQGNVSEGMKGIVLFVSKVLEEP
KDFSCETEDFKTLHCTWDPGTDTALGWSKQPSQSYTLFESFSGEKKLCTHKNWCNWQITQ
DSQETYNFTLIAENYLRKRSVNILFNLTHRVYLMNPFSVNFENVNATNAIMTWKVHSIRN
NFTYLCQIELHGEGKMMQYNVSIKVNGEYFLSELEPATEYMARVRCADASHFWKWSEWSG
QNFTTLEAAPSEAPDVWRIVSLEPGNHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSS
SELHSIPAPANSTKLILDRCSYQICVIANNSVGASPASVIVISADPENKEVEEERIAGTE
GGFSLSWKPQPGDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFR
IYGLSTKRIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGY
HVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSA
GEGPSATFTKVTTPDEHSSMLIHILLPMVFCVLLIMVMCYLKSQWIKETCYPDIPDPYKS
SILSLIKFKENPHLIIMNVSDCIPDAIEVVSKPEGTKIQFLGTRKSLTETELTKPNYLYL
LPTEKNHSGPGPCICFENLTYNQAASDSGSCGHVPVSPKAPSMLGLMTSPENVLKALEKN
YMNSLGEIPAGETSLNYVSQLASPMFGDKDSLPTNPVEAPHCSEYKMQMAVSLRLALPPP
TENSSLSSITLLDPGEHYC
NT seq 2940 nt   +upstreamnt  +downstreamnt
atggctctatttgcagtctttcagacaacattcttcttaacattgctgtccttgaggact
taccagagtgaagtcttggctgaacgtttaccattgactcctgtatcacttaaagtttcc
accaattctacgcgtcagagtttgcacttacaatggactgtccacaaccttccttatcat
caggaattgaaaatggtatttcagatccagatcagtaggattgaaacatccaatgtcatc
tgggtggggaattacagcaccactgtgaagtggaaccaggttctgcattggagctgggaa
tctgagctccctttggaatgtgccacacactttgtaagaataaagagtttggtggacgat
gccaagttccctgagccaaatttctggagcaactggagttcctgggaggaagtcagtgta
caagattctactggacaggatatattgttcgttttccctaaagataagctggtggaagaa
ggcaccaatgttaccatttgttacgtttctaggaacattcaaaataatgtatcctgttat
ttggaagggaaacagattcatggagaacaacttgatccacatgtaactgcattcaacttg
aatagtgtgcctttcattaggaataaagggacaaatatctattgtgaggcaagtcaagga
aatgtcagtgaaggcatgaaaggcatcgttctttttgtctcaaaagtacttgaggagccc
aaggacttttcttgtgaaaccgaggacttcaagactttgcactgtacttgggatcctggg
acggacactgccttggggtggtctaaacaaccttcccaaagctacactttatttgaatca
ttttctggggaaaagaaactttgtacacacaaaaactggtgtaattggcaaataactcaa
gactcacaagaaacctataacttcacactcatagctgaaaattacttaaggaagagaagt
gtcaatatcctttttaacctgactcatcgagtttatttaatgaatccttttagtgtcaac
tttgaaaatgtaaatgccacaaatgccatcatgacctggaaggtgcactccataaggaat
aatttcacatatttgtgtcagattgaactccatggtgaaggaaaaatgatgcaatacaat
gtttccatcaaggtgaacggtgagtacttcttaagtgaactggaacctgccacagagtac
atggcgcgagtacggtgtgctgatgccagccacttctggaaatggagtgaatggagtggt
cagaacttcaccacacttgaagctgctccctcagaggcccctgatgtctggagaattgtg
agcttggagccaggaaatcatactgtgaccttattctggaagccattatcaaaactgcat
gccaatggaaagatcctgttctataatgtagttgtagaaaacctagacaaaccatccagt
tcagagctccattccattccagcaccagccaacagcacaaaactaatccttgacaggtgt
tcctaccaaatctgcgtcatagccaacaacagtgtgggtgcttctcctgcttctgtaata
gtcatctctgcagaccccgaaaacaaagaggttgaggaagaaagaattgcaggcacagag
ggtggattctctctgtcttggaaaccccaacctggagatgttataggctatgttgtggac
tggtgtgaccatacccaggatgtgctcggtgatttccagtggaagaatgtaggtcccaat
accacaagcacagtcattagcacagatgcttttaggccaggagttcgatatgacttcaga
atttatgggttatctacaaaaaggattgcttgtttattagagaaaaaaacaggatactct
caggaacttgctccttcagacaaccctcacgtgctggtggatacattgacatcccactcc
ttcactctgagttggaaagattactctactgaatctcaacctggttttatacaagggtac
catgtctatctgaaatccaaggcgaggcagtgccacccacgatttgaaaaggcagttctt
tcagatggttcagaatgttgcaaatacaaaattgacaacccggaagaaaaggcattgatt
gtggacaacctaaagccagaatccttctatgagtttttcatcactccattcactagtgct
ggtgaaggccccagtgctacgttcacgaaggtcacgactccggatgaacactcctcgatg
ctgattcatatcctactgcccatggttttctgcgtcttgctcatcatggtcatgtgctac
ttgaaaagtcagtggatcaaggagacctgttatcctgacatccctgacccttacaagagc
agcatcctgtcattaataaaattcaaggagaaccctcacctaataataatgaatgtcagt
gactgtatcccagatgctattgaagttgtaagcaagccagaagggacaaagatacagttc
ctaggcactaggaagtcactcacagaaaccgagttgactaagcctaactacctttatctc
cttccaacagaaaagaatcactctggccctggcccctgcatctgttttgagaacttgacc
tataaccaggcagcttctgactctggctcttgtggccatgttccagtatccccaaaagcc
ccaagtatgctgggactaatgacctcacctgaaaatgtactaaaggcactagaaaaaaac
tacatgaactccctgggagaaatcccagctggagaaacaagtttgaattatgtgtcccag
ttggcttcacccatgtttggagacaaggacagtctcccaacaaacccagtagaggcacca
cactgttcagagtataaaatgcaaatggcagtctccctgcgtcttgccttgcctcccccg
accgagaatagcagcctctcctcaattacccttttagatccaggtgaacactactgctaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (27)   
   KEGG ORTHOLOGY (1)   
   RefGene (20)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (26)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (24)   
DNA sequence (60)   
   RefSeq(nuc) (30)   
   GenBank (15)   
   EMBL (15)   
Protein domain (5)   
   Pfam (5)   
All databases (130)   

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