KEGG   Homo sapiens (human): 9294
Entry
9294              CDS       T01001                                 
Symbol
S1PR2, AGR16, DFNB68, EDG-5, EDG5, Gpcr13, H218, LPB2, S1P2
Name
(RefSeq) sphingosine-1-phosphate receptor 2
  KO
K04292  sphingosine 1-phosphate receptor 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04071  Sphingolipid signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
Disease
H00605  Deafness, autosomal recessive
Drug target
Amiselimod (DG02399): D10904 D10905
Ozanimod (DG02827): D10967<US> D10968
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    9294 (S1PR2)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    9294 (S1PR2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    9294 (S1PR2)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Lipid
   Sphingolipid
    9294 (S1PR2)
SSDB
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx DUF2208
Other DBs
NCBI-GeneID: 9294
NCBI-ProteinID: NP_004221
OMIM: 605111
HGNC: 3169
Ensembl: ENSG00000267534
UniProt: O95136
Structure
Position
19:complement(10221433..10231331)
AA seq 353 aa
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVAR
NSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASV
FSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACS
TVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLG
VFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVL
RPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
NT seq 1062 nt   +upstreamnt  +downstreamnt
atgggcagcttgtactcggagtacctgaaccccaacaaggtccaggaacactataattat
accaaggagacgctggaaacgcaggagacgacctcccgccaggtggcctcggccttcatc
gtcatcctctgttgcgccattgtggtggaaaaccttctggtgctcattgcggtggcccga
aacagcaagttccactcggcaatgtacctgtttctgggcaacctggccgcctccgatcta
ctggcaggcgtggccttcgtagccaataccttgctctctggctctgtcacgctgaggctg
acgcctgtgcagtggtttgcccgggagggctctgccttcatcacgctctcggcctctgtc
ttcagcctcctggccatcgccattgagcgccacgtggccattgccaaggtcaagctgtat
ggcagcgacaagagctgccgcatgcttctgctcatcggggcctcgtggctcatctcgctg
gtcctcggtggcctgcccatccttggctggaactgcctgggccacctcgaggcctgctcc
actgtcctgcctctctacgccaagcattatgtgctgtgcgtggtgaccatcttctccatc
atcctgttggccatcgtggccctgtacgtgcgcatctactgcgtggtccgctcaagccac
gctgacatggccgccccgcagacgctagccctgctcaagacggtcaccatcgtgctaggc
gtctttatcgtctgctggctgcccgccttcagcatcctccttctggactatgcctgtccc
gtccactcctgcccgatcctctacaaagcccactactttttcgccgtctccaccctgaat
tccctgctcaaccccgtcatctacacgtggcgcagccgggacctgcggcgggaggtgctt
cggccgctgcagtgctggaggccgggggtgggggtgcaaggacggaggcggggcgggacc
ccgggccaccacctcctgccactccgcagctccagctccctggagaggggcatgcacatg
cccacgtcacccacgtttctggagggcaacacggtggtctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Drug (4)   
   KEGG DRUG (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (9)   
   RefSeq(nuc) (1)   
   GenBank (4)   
   EMBL (4)   
3D Structure (1)   
   PDB (1)   
Protein domain (3)   
   Pfam (3)   
All databases (46)   

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