KEGG   Homo sapiens (human): 9312
Entry
9312              CDS       T01001                                 
Symbol
KCNB2, KV2.2
Name
(RefSeq) potassium voltage-gated channel subfamily B member 2
  KO
K04886  potassium voltage-gated channel Shab-related subfamily B member 2
Organism
hsa  Homo sapiens (human)
Drug target
Amifampridine: D10228 D10689<US>
Fampridine: D04127<US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    9312 (KCNB2)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Potassium channel, voltage-gated (Kv)
   9312 (KCNB2)
SSDB
Motif
Pfam: Kv2channel Ion_trans BTB_2 Ion_trans_2 DUF5843 DUF4790 Sld5
Other DBs
NCBI-GeneID: 9312
NCBI-ProteinID: NP_004761
OMIM: 607738
HGNC: 6232
Ensembl: ENSG00000182674
UniProt: Q92953
Position
8:72537225..72938349
AA seq 911 aa
MAEKAPPGLNRKTSRSTLSLPPEPVDIIRSKTCSRRVKINVGGLNHEVLWRTLDRLPRTR
LGKLRDCNTHESLLEVCDDYNLNENEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFG
QELDYWGIDEIYLESCCQARYHQKKEQMNEELRREAETMREREGEEFDNTCCPDKRKKLW
DLLEKPNSSVAAKILAIVSILFIVLSTIALSLNTLPELQETDEFGQLNDNRQLAHVEAVC
IAWFTMEYLLRFLSSPNKWKFFKGPLNVIDLLAILPYYVTIFLTESNKSVLQFQNVRRVV
QIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDE
DATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNF
SEFYKEQKRQEKAIKRREALERAKRNGSIVSMNLKDAFARSMELIDVAVEKAGESANTKD
SADDNHLSPSRWKWARKALSETSSNKSFENKYQEVSQKDSHEQLNNTSSSSPQHLSAQKL
EMLYNEITKTQPHSHPNPDCQEKPERPSAYEEEIEMEEVVCPQEQLAVAQTEVIVDMKST
SSIDSFTSCATDFTETERSPLPPPSASHLQMKFPTDLPGTEEHQRARGPPFLTLSREKGP
AARDGTLEYAPVDITVNLDASGSQCGLHSPLQSDNATDSPKSSLKGSNPLKSRSLKVNFK
ENRGSAPQTPPSTARPLPVTTADFSLTTPQHISTILLEETPSQGDRPLLGTEVSAPCQGP
SKGLSPRFPKQKLFPFSSRERRSFTEIDTGDDEDFLELPGAREEKQVDSSPNCFADKPSD
GRDPLREEGSVGSSSPQDTGHNCRQDIYHAVSEVKKDSSQEGCKMENHLFAPEIHSNPGD
TGYCPTRETSM
NT seq 2736 nt   +upstreamnt  +downstreamnt
atggcagaaaaggctcccccgggcttaaacaggaagacttcaaggtcgacactttccctt
cctccagagcctgtggacattatccggagcaaaacatgctccaggagagttaagatcaat
gtggggggcctcaaccacgaagtcctgtggagaacgctggacaggctgcccaggacgcgc
ctggggaagcttcgagactgcaacacacacgagagcctcctggaagtgtgcgacgactat
aatctgaacgagaacgagtatttctttgatcggcatccaggagccttcacttccatttta
aatttctaccggaccgggaaactccatatgatggaagaaatgtgtgcactttcgtttggc
caagaacttgattactgggggattgatgagatctacttggagtcctgctgccaggccaga
tatcatcaaaaaaaagaacaaatgaacgaagaactgaggcgagaggcagagactatgcga
gagcgagaaggagaagagtttgataatacctgctgccctgataaaaggaagaaactgtgg
gacttgctggagaaacctaactcatcagtggctgcaaagatcctggccatcgtgtctatc
ctgttcattgtgctttccaccattgctttgtctctcaatacgctgccggagctgcaggaa
acggacgaatttggacaactcaatgacaaccgccaattagcacacgtggaggctgtgtgt
attgcatggtttaccatggagtaccttttgcgattcttatcctcaccaaataaatggaag
ttcttcaaaggcccactgaatgtcattgatttgctggccatcttgccgtactatgtcacc
atttttctgacggagtccaacaagagcgtgctgcagttccaaaacgtgaggcgcgtggtc
cagatcttccgaatcatgcgcatcctcaggatcctgaaactcgccaggcattcgacaggc
ctgcagtctctgggtttcacccttaggcggagttacaatgaattgggcttgttgatattg
tttctggccatggggataatgatattttccagcctggtattttttgctgagaaggatgaa
gatgctaccaagttcaccagtatccctgcatcattttggtgggccaccatcaccatgacc
actgttggctatggtgacatttaccctaaaacattactagggaaaattgtgggaggtctg
tgctgtattgctggggttctggttattgcccttcctatcccaattattgtgaacaatttt
tctgagttttacaaggagcagaaacgccaagagaaagcaattaaaaggagggaggctctt
gagcgggccaaaaggaacggaagcatcgtttctatgaacttaaaagatgccttcgctcga
agtatggaactgatagatgtggctgttgagaaggccggagagtccgccaacacaaaggac
tccgccgacgataatcacctgtcgccaagccggtggaagtgggccaggaaggctctgtcg
gaaacaagctccaacaagtctttcgagaataagtaccaggaggttagccaaaaagactcc
cacgagcagctgaacaacacgtcttcctccagcccacagcatctgagtgcccagaaactg
gagatgctatacaatgaaatcaccaagacacagcctcattctcacccaaacccagactgc
caagaaaagcctgagaggccatctgcatatgaagaagagattgaaatggaagaagtggtg
tgtccacaggagcagctggccgtggcacagaccgaggtcattgtggacatgaagagcacc
tccagcatcgacagcttcaccagctgtgccaccgacttcacagagacagagagatcgccg
ctgccgccgccctccgcctctcacttgcagatgaagttcccaaccgacctcccagggaca
gaagagcaccaaagagctaggggccccccgtttctaactctatccagagagaaaggacct
gctgccagggatggcacgctggagtatgccccagttgacataactgtgaacctcgatgcc
agtggctcccagtgtgggctacatagtcctttgcagtctgacaatgccaccgacagtcct
aagagctctctaaaaggcagcaacccactaaagtccagatccctcaaagtgaactttaag
gaaaatagaggcagtgcaccacagaccccgcccagcacagccaggccactgccagtcacc
acagctgacttttcgctcactaccccgcagcacatcagtaccatcctcttagaagaaacc
ccctcccagggagacagacccttgctgggcactgaggtttcagcgccttgtcagggacct
tccaaagggctgtcccccaggtttcccaagcagaaactgttccctttctcttcaagagag
aggaggagcttcactgaaatagatactggtgacgacgaagacttcttagagctcccaggg
gcaagggaggagaagcaggtggactccagcccaaattgctttgcagataagcctagtgat
gggagagaccctttaagagaagagggcagtgtgggctcttcctccccgcaggacacaggt
cacaactgtaggcaagacatttaccatgctgtgagtgaagtcaaaaaggacagtagtcaa
gaagggtgcaagatggaaaatcacttgtttgccccagaaattcattccaacccaggagac
acaggttattgtcccacacgtgaaaccagcatgtga

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Ontology (2)   
   KEGG BRITE (2)   
Disease (1)   
   OMIM (1)   
Drug (3)   
   KEGG DRUG (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (11)   
   RefSeq(nuc) (3)   
   GenBank (4)   
   EMBL (4)   
Protein domain (7)   
   Pfam (7)   
All databases (49)   

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