KEGG   Homo sapiens (human): 945
Entry
945               CDS       T01001                                 
Symbol
CD33, CD33rSiglec, SIGLEC-3, SIGLEC3, p67
Name
(RefSeq) CD33 molecule
  KO
K06473  CD33 antigen
Organism
hsa  Homo sapiens (human)
Pathway
hsa04640  Hematopoietic cell lineage
Drug target
Avitotamig: D12721
Eluvixtamab: D12152
Emerfetamab: D12141
Gemtuzumab ozogamicin: D03259<JP/US>
Vadastuximab: D11294
Vadastuximab talirine: D11295
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    945 (CD33)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    945 (CD33)
   04091 Lectins [BR:hsa04091]
    945 (CD33)
CD molecules [BR:hsa04090]
 Proteins
  945 (CD33)
Lectins [BR:hsa04091]
 I-type lectins (Siglecs)
  945 (CD33)
SSDB
Motif
Pfam: V-set ig Ig_3 C2-set_2 DUF998
Other DBs
NCBI-GeneID: 945
NCBI-ProteinID: NP_001763
OMIM: 159590
HGNC: 1659
Ensembl: ENSG00000105383
UniProt: P20138 Q546G0
Structure
Position
19:51211076..51240016
AA seq 364 aa
MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYW
FREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRM
ERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWL
SAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQNPTT
GIFPGDGSGKQETRAGVVHGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTH
PTTGSASPKHQKKSKLHGPTETSSCSGAAPTVEMDEELHYASLNFHGMNPSKDTSTEYSE
VRTQ
NT seq 1095 nt   +upstreamnt  +downstreamnt
atgccgctgctgctactgctgcccctgctgtgggcaggggccctggctatggatccaaat
ttctggctgcaagtgcaggagtcagtgacggtacaggagggtttgtgcgtcctcgtgccc
tgcactttcttccatcccataccctactacgacaagaactccccagttcatggttactgg
ttccgggaaggagccattatatccagggactctccagtggccacaaacaagctagatcaa
gaagtacaggaggagactcagggcagattccgcctccttggggatcccagtaggaacaac
tgctccctgagcatcgtagacgccaggaggagggataatggttcatacttctttcggatg
gagagaggaagtaccaaatacagttacaaatctccccagctctctgtgcatgtgacagac
ttgacccacaggcccaaaatcctcatccctggcactctagaacccggccactccaaaaac
ctgacctgctctgtgtcctgggcctgtgagcagggaacacccccgatcttctcctggttg
tcagctgcccccacctccctgggccccaggactactcactcctcggtgctcataatcacc
ccacggccccaggaccacggcaccaacctgacctgtcaggtgaagttcgctggagctggt
gtgactacggagagaaccatccagctcaacgtcacctatgttccacagaacccaacaact
ggtatctttccaggagatggctcagggaaacaagagaccagagcaggagtggttcatggg
gccattggaggagctggtgttacagccctgctcgctctttgtctctgcctcatcttcttc
atagtgaagacccacaggaggaaagcagccaggacagcagtgggcaggaatgacacccac
cctaccacagggtcagcctccccgaaacaccagaagaagtccaagttacatggccccact
gaaacctcaagctgttcaggtgccgcccctactgtggagatggatgaggagctgcattat
gcttccctcaactttcatgggatgaatccttccaaggacacctccaccgaatactcagag
gtcaggacccagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Drug (6)   
   KEGG DRUG (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (19)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (16)   
DNA sequence (46)   
   RefSeq(nuc) (18)   
   GenBank (14)   
   EMBL (14)   
3D Structure (8)   
   PDB (8)   
Protein domain (5)   
   Pfam (5)   
All databases (109)   

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