KEGG   Homo sapiens (human): 9517
Entry
9517              CDS       T01001                                 
Symbol
SPTLC2, HSN1C, LCB2, LCB2A, NSAN1C, SPT2, hLCB2a
Name
(RefSeq) serine palmitoyltransferase long chain base subunit 2
  KO
K00654  serine palmitoyltransferase [EC:2.3.1.50]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00600  Sphingolipid metabolism
hsa01100  Metabolic pathways
hsa04071  Sphingolipid signaling pathway
Module
hsa_M00094  Ceramide biosynthesis
hsa_M00099  Sphingosine biosynthesis
Disease
H00265  Hereditary sensory and autonomic neuropathy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    9517 (SPTLC2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    9517 (SPTLC2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:hsa01007]
    9517 (SPTLC2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.50  serine C-palmitoyltransferase
     9517 (SPTLC2)
Amino acid related enzymes [BR:hsa01007]
 Aminotransferase (transaminase)
  Class II
   9517 (SPTLC2)
SSDB
Motif
Pfam: Aminotran_1_2 Beta_elim_lyase Aminotran_5
Other DBs
NCBI-GeneID: 9517
NCBI-ProteinID: NP_004854
OMIM: 605713
HGNC: 11278
Ensembl: ENSG00000100596
UniProt: O15270
Structure
Position
14:complement(77505997..77616637)
AA seq 562 aa
MRPEPGGCCCRRTVRANGCVANGEVRNGYVRSSAAAAAAAAAGQIHHVTQNGGLYKRPFN
EAFEETPMLVAVLTYVGYGVLTLFGYLRDFLRYWRIEKCHHATEREEQKDFVSLYQDFEN
FYTRNLYMRIRDNWNRPICSVPGARVDIMERQSHDYNWSFKYTGNIIKGVINMGSYNYLG
FARNTGSCQEAAAKVLEEYGAGVCSTRQEIGNLDKHEELEELVARFLGVEAAMAYGMGFA
TNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQ
PRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPTGRGVV
EYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSLSPPVVEQII
TSMKCIMGQDGTSLGKECVQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIG
AFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKYS
RHRLVPLLDRPFDETTYEETED
NT seq 1689 nt   +upstreamnt  +downstreamnt
atgcggccggagcccggaggctgctgctgccgccgcacggtgcgggcgaatggctgcgtg
gcgaacggggaagtacggaacgggtacgtgaggagcagcgctgcagccgcagccgcagcc
gccgccggccagatccatcatgttacacaaaatggaggactatataaaagaccgtttaat
gaagcttttgaagaaacaccaatgctggttgctgtgctcacgtatgtggggtatggcgta
ctcaccctctttggatatcttcgagatttcttgaggtattggagaattgaaaagtgtcac
catgcaacagaaagagaagaacaaaaggactttgtgtcattgtatcaagattttgaaaac
ttttatacaaggaatctgtacatgaggataagagacaactggaatcggccaatctgtagt
gtgcctggagccagggtggacatcatggagagacagtctcatgattataactggtccttc
aagtatacagggaatataataaagggtgttataaacatgggttcctacaactatcttgga
tttgcacggaatactggatcatgtcaagaagcagccgccaaagtccttgaggagtatgga
gctggagtgtgcagtactcggcaggaaattggaaacctggacaagcatgaagaactagag
gagcttgtagcaaggttcttaggagtagaagctgctatggcgtatggcatgggatttgca
acgaattcaatgaacattcctgctcttgttggcaaaggttgcctgattctgagtgatgaa
ctgaatcatgcatcactggttctgggagccagactgtcaggagcaaccattagaatcttc
aaacacaacaatatgcaaagcctagagaagctattgaaagatgccattgtttatggtcag
cctcggacacgaaggccctggaagaaaattctcatccttgtggaaggaatatatagcatg
gagggatctattgttcgtcttcctgaagtgattgccctcaagaagaaatacaaggcatac
ttgtatctggatgaggctcacagcattggcgccctgggccccacaggccggggtgtggtg
gagtactttggcctggatcccgaggatgtggatgttatgatgggaacgttcacaaagagt
tttggtgcttctggaggatatattggaggcaagaaggagctgatagactacctgcgaaca
cattctcatagtgcagtgtatgccacgtcattgtcacctcctgtagtggagcagatcatc
acctccatgaagtgcatcatggggcaggatggcaccagccttggtaaagagtgtgtacaa
cagttagctgaaaacaccaggtatttcaggagacgcctgaaagagatgggcttcatcatc
tatggaaatgaagactctccagtagtgcctttgatgctctacatgcctgccaaaattggc
gcctttggacgggagatgctgaagcggaacatcggtgtcgttgtggttggatttcctgcc
accccaattattgagtccagagccaggttttgcctgtcagcagctcataccaaagaaata
cttgatactgctttaaaggagatagatgaagttggggacctattgcagctgaagtattcc
cgtcatcggttggtacctctactggacaggccctttgacgagacgacgtatgaagaaaca
gaagactga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (19)   
   RefSeq(nuc) (3)   
   GenBank (8)   
   EMBL (8)   
3D Structure (17)   
   PDB (17)   
Protein domain (3)   
   Pfam (3)   
All databases (73)   

Download RDF
DBGET integrated database retrieval system