KEGG   Homo sapiens (human): 9536
Entry
9536              CDS       T01001                                 
Symbol
PTGES, MGST-IV, MGST1-L1, MGST1L1, MPGES, PGES, PIG12, PP102, PP1294, TP53I12, mPGES-1
Name
(RefSeq) prostaglandin E synthase
  KO
K15729  microsomal prostaglandin-E synthase 1 [EC:5.3.99.3]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00590  Arachidonic acid metabolism
hsa01100  Metabolic pathways
Drug target
Aceclofenac: D01545
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    9536 (PTGES)
Enzymes [BR:hsa01000]
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.99  Other intramolecular oxidoreductases
    5.3.99.3  prostaglandin-E synthase
     9536 (PTGES)
SSDB
Motif
Pfam: MAPEG DUF4406
Other DBs
NCBI-GeneID: 9536
NCBI-ProteinID: NP_004869
OMIM: 605172
HGNC: 9599
Ensembl: ENSG00000148344
UniProt: O14684
Structure
Position
9:complement(129738349..129753042)
AA seq 152 aa
MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCR
SDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGK
LRAPIRSVTYTLAQLPCASMALQILWEAARHL
NT seq 459 nt   +upstreamnt  +downstreamnt
atgcctgcccacagcctggtgatgagcagcccggccctcccggccttcctgctctgcagc
acgctgctggtcatcaagatgtacgtggtggccatcatcacgggccaagtgaggctgcgg
aagaaggcctttgccaaccccgaggatgccctgagacacggaggcccccagtattgcagg
agcgaccccgacgtggaacgctgcctcagggcccaccggaacgacatggagaccatctac
cccttccttttcctgggcttcgtctactcctttctgggtcctaacccttttgtcgcctgg
atgcacttcctggtcttcctcgtgggccgtgtggcacacaccgtggcctacctggggaag
ctgcgggcacccatccgctccgtgacctacaccctggcccagctcccctgcgcctccatg
gctctgcagatcctctgggaagcggcccgccacctgtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Chemical substance (2)   
   KEGG COMPOUND (2)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (28)   
   RefSeq(nuc) (2)   
   GenBank (13)   
   EMBL (13)   
3D Structure (18)   
   PDB (18)   
Protein domain (2)   
   Pfam (2)   
All databases (76)   

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