KEGG   Homo sapiens (human): 9620
Entry
9620              CDS       T01001                                 
Symbol
CELSR1, ADGRC1, CDHF9, FMI2, HFMI2, LMPHM9, ME2
Name
(RefSeq) cadherin EGF LAG seven-pass G-type receptor 1
  KO
K04600  cadherin EGF LAG seven-pass G-type receptor 1
Organism
hsa  Homo sapiens (human)
Disease
H00535  Lymphatic malformation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    9620 (CELSR1)
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    9620 (CELSR1)
   04515 Cell adhesion molecules [BR:hsa04515]
    9620 (CELSR1)
Peptidases and inhibitors [BR:hsa01002]
 Mixed peptidases
  Family P2
   9620 (CELSR1)
G protein-coupled receptors [BR:hsa04030]
 Adhesion receptor family
  Cadherin EGF LAG (CELSR)
   9620 (CELSR1)
Cell adhesion molecules [BR:hsa04515]
 Cadherins
  Major cadherins
   9620 (CELSR1)
SSDB
Motif
Pfam: Cadherin 7tm_2 GAIN Laminin_G_2 Laminin_G_1 Cadherin_3 GPS EGF HRM Laminin_EGF Dicty_CAR Cadherin_4 Cadherin_pro RET_CLD1 hEGF Frizzled Laminin_G_3
Other DBs
NCBI-GeneID: 9620
NCBI-ProteinID: NP_055061
OMIM: 604523
HGNC: 1850
Ensembl: ENSG00000075275
UniProt: Q9NYQ6
Structure
Position
22:complement(46361174..46537620)
AA seq 3014 aa
MAPPPPPVLPVLLLLAAAAALPAMGLRAAAWEPRVPGGTRAFALRPGCTYAVGAACTPRA
PRELLDVGRDGRLAGRRRVSGAGRPLPLQVRLVARSAPTALSRRLRARTHLPGCGARARL
CGTGARLCGALCFPVPGGCAAAQHSALAAPTTLPACRCPPRPRPRCPGRPICLPPGGSVR
LRLLCALRRAAGAVRVGLALEAATAGTPSASPSPSPPLPPNLPEARAGPARRARRGTSGR
GSLKFPMPNYQVALFENEPAGTLILQLHAHYTIEGEEERVSYYMEGLFDERSRGYFRIDS
ATGAVSTDSVLDRETKETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPVFEQSEYRE
RVRENLEVGYEVLTIRASDRDSPINANLRYRVLGGAWDVFQLNESSGVVSTRAVLDREEA
AEYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPEDVGLNTAVLR
VQATDRDQGQNAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFEDVQKYSLSIKAQDGG
RPPLINSSGVVSVQVLDVNDNEPIFVSSPFQATVLENVPLGYPVVHIQAVDADSGENARL
HYRLVDTASTFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELDREEVEHYSFGVEAV
DHGSPPMSSSTSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSVLTLQARDRDANSVI
TYQLTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASDGTRSHTAHVLINVT
DANTHRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDTGENARITYVIQDPVPQFRIDPD
SGTMYTMMELDYENQVAYTLTIMAQDNGIPQKSDTTTLEILILDANDNAPQFLWDFYQGS
IFEDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDGDGDFYIEPTSGVIRTQRRLDREN
VAVYNLWALAVDRGSPTPLSASVEIQVTILDINDNAPMFEKDELELFVEENNPVGSVVAK
IRANDPDEGPNAQIMYQIVEGDMRHFFQLDLLNGDLRAMVELDFEVRREYVLVVQATSAP
LVSRATVHILLVDQNDNPPVLPDFQILFNNYVTNKSNSFPTGVIGCIPAHDPDVSDSLNY
TFVQGNELRLLLLDPATGELQLSRDLDNNRPLEALMEVSVSDGIHSVTAFCTLRVTIITD
DMLTNSITVRLENMSQEKFLSPLLALFVEGVAAVLSTTKDDVFVFNVQNDTDVSSNILNV
TFSALLPGGVRGQFFPSEDLQEQIYLNRTLLTTISTQRVLPFDDNICLREPCENYMKCVS
VLRFDSSAPFLSSTTVLFRPIHPINGLRCRCPPGFTGDYCETEIDLCYSDPCGANGRCRS
REGGYTCECFEDFTGEHCEVDARSGRCANGVCKNGGTCVNLLIGGFHCVCPPGEYERPYC
EVTTRSFPPQSFVTFRGLRQRFHFTISLTFATQERNGLLLYNGRFNEKHDFIALEIVDEQ
VQLTFSAGETTTTVAPKVPSGVSDGRWHSVQVQYYNKPNIGHLGLPHGPSGEKMAVVTVD
DCDTTMAVRFGKDIGNYSCAAQGTQTGSKKSLDLTGPLLLGGVPNLPEDFPVHNRQFVGC
MRNLSVDGKNVDMAGFIANNGTREGCAARRNFCDGRRCQNGGTCVNRWNMYLCECPLRFG
GKNCEQAMPHPQLFSGESVVSWSDLNIIISVPWYLGLMFRTRKEDSVLMEATSGGPTSFR
LQILNNYLQFEVSHGPSDVESVMLSGLRVTDGEWHHLLIELKNVKEDSEMKHLVTMTLDY
GMDQNKADIGGMLPGLTVRSVVVGGASEDKVSVRRGFRGCMQGVRMGGTPTNVATLNMNN
ALKVRVKDGCDVDDPCTSSPCPPNSRCHDAWEDYSCVCDKGYLGINCVDACHLNPCENMG
ACVRSPGSPQGYVCECGPSHYGPYCENKLDLPCPRGWWGNPVCGPCHCAVSKGFDPDCNK
TNGQCQCKENYYKLLAQDTCLPCDCFPHGSHSRTCDMATGQCACKPGVIGRQCNRCDNPF
AEVTTLGCEVIYNGCPKAFEAGIWWPQTKFGQPAAVPCPKGSVGNAVRHCSGEKGWLPPE
LFNCTTISFVDLRAMNEKLSRNETQVDGARALQLVRALRSATQHTGTLFGNDVRTAYQLL
GHVLQHESWQQGFDLAATQDADFHEDVIHSGSALLAPATRAAWEQIQRSEGGTAQLLRRL
EGYFSNVARNVRRTYLRPFVIVTANMILAVDIFDKFNFTGARVPRFDTIHEEFPRELESS
VSFPADFFRPPEEKEGPLLRPAGRRTTPQTTRPGPGTEREAPISRRRRHPDDAGQFAVAL
VIIYRTLGQLLPERYDPDRRSLRLPHRPIINTPMVSTLVYSEGAPLPRPLERPVLVEFAL
LEVEERTKPVCVFWNHSLAVGGTGGWSARGCELLSRNRTHVACQCSHTASFAVLMDISRR
ENGEVLPLKIVTYAAVSLSLAALLVAFVLLSLVRMLRSNLHSIHKHLAVALFLSQLVFVI
GINQTENPFLCTVVAILLHYIYMSTFAWTLVESLHVYRMLTEVRNIDTGPMRFYYVVGWG
IPAIVTGLAVGLDPQGYGNPDFCWLSLQDTLIWSFAGPIGAVIIINTVTSVLSAKVSCQR
KHHYYGKKGIVSLLRTAFLLLLLISATWLLGLLAVNRDALSFHYLFAIFSGLQGPFVLLF
HCVLNQEVRKHLKGVLGGRKLHLEDSATTRATLLTRSLNCNTTFGDGPDMLRTDLGESTA
SLDSIVRDEGIQKLGVSSGLVRGSHGEPDASLMPRSCKDPPGHDSDSDSELSLDEQSSSY
ASSHSSDSEDDGVGAEEKWDPARGAVHSTPKGDAVANHVPAGWPDQSLAESDSEDPSGKP
RLKVETKVSVELHREEQGSHRGEYPPDQESGGAARLASSQPPEQRKGILKNKVTYPPPLT
LTEQTLKGRLREKLADCEQSPTSSRTSSLGSGGPDCAITVKSPGREPGRDHLNGVAMNVR
TGSAQADGSDSEKP
NT seq 9045 nt   +upstreamnt  +downstreamnt
atggcgccgccgccgccgcccgtgctgcccgtgctgctgctcctggccgccgccgccgcc
ctgccggcgatggggctgcgagcggccgcctgggagccgcgcgtacccggcgggacccgc
gccttcgccctccggcccggctgtacctacgcggtgggcgccgcttgcacgccccgggcg
ccgcgggagctgctggacgtgggccgcgatgggcggctggcaggacgtcggcgcgtctcg
ggcgcggggcgcccgctgccgctgcaagtccgcttggtggcccgcagtgccccgacggcg
ctgagccgccgcctgcgggcgcgcacgcaccttcccggctgcggagcccgtgcccggctc
tgcggaaccggtgcccggctctgcggggcgctctgcttccccgtccccggcggctgcgcg
gccgcgcagcattcggcgctcgcagctccgaccaccttacccgcctgccgctgcccgccg
cgccccaggccccgctgtcccggccgtcccatctgcctgccgccgggcggctcggtccgc
ctgcgtctgctgtgcgccctgcggcgcgcggctggcgccgtccgggtgggactggcgctg
gaggccgccaccgcggggacgccctccgcgtcgccatccccatcgccgcccctgccgccg
aacttgcccgaagcccgggcggggccggcgcgacgggcccggcggggcacgagcggcaga
gggagcctgaagtttccgatgcccaactaccaggtggcgttgtttgagaacgaaccggcg
ggcaccctcatcctccagctgcacgcgcactacaccatcgagggcgaggaggagcgcgtg
agctattacatggaggggctgttcgacgagcgctcccggggctacttccgaatcgactct
gccacgggcgccgtgagcacggacagcgtactggaccgcgagaccaaggagacgcacgtc
ctcagggtgaaagccgtggactacagtacgccgccgcgctcggccaccacctacatcact
gtcttggtcaaagacaccaacgaccacagcccggtcttcgagcagtcggagtaccgcgag
cgcgtgcgggagaacctggaggtgggctacgaggtgctgaccatccgcgccagcgaccgc
gactcgcccatcaacgccaacttgcgttaccgcgtgttggggggcgcgtgggacgtcttc
cagctcaacgagagctctggcgtggtgagcacacgggcggtgctggaccgggaggaggcg
gccgagtaccagctcctggtggaggccaacgaccaggggcgcaatccgggcccgctcagt
gccacggccaccgtgtacatcgaggtggaggacgagaacgacaactacccccagttcagc
gagcagaactacgtggtccaggtgcccgaggacgtggggctcaacacggctgtgctgcga
gtgcaggccacggaccgggaccagggccagaacgcggccattcactacagcatcctcagc
gggaacgtggccggccagttctacctgcactcgctgagcgggatcctggatgtgatcaac
cccttggatttcgaggatgtccagaaatactcgctgagcattaaggcccaggatgggggc
cggcccccgctcatcaattcttcaggggtggtgtctgtgcaggtgctggatgtcaacgac
aacgagcctatctttgtgagcagccccttccaggccacggtgctggagaatgtgcccctg
ggctaccccgtggtgcacattcaggcggtggacgcggactctggagagaacgcccggctg
cactatcgcctggtggacacggcctccacctttctggggggcggcagcgctgggcctaag
aatcctgcccccacccctgacttccccttccagatccacaacagctccggttggatcaca
gtgtgtgccgagctggaccgcgaggaggtggagcactacagcttcggggtggaggcggtg
gaccacggctcgccccccatgagctcctccaccagcgtgtccatcacggtgctggacgtg
aatgacaacgacccggtgttcacgcagcccacctacgagcttcgtctgaatgaggatgcg
gccgtggggagcagcgtgctgaccctgcaggcccgcgaccgtgacgccaacagtgtgatt
acctaccagctcacaggcggcaacacccggaaccgctttgcactcagcagccagagaggg
ggcggcctcatcaccctggcgctacctctggactacaagcaggagcagcagtacgtgctg
gcggtgacagcatccgacggcacacggtcgcacactgcgcatgtcctaatcaacgtcact
gatgccaacacccacaggcctgtctttcagagctcccattacacagtgagtgtcagtgag
gacaggcctgtgggcacctccattgctaccctcagtgccaacgatgaggacacaggagag
aatgcccgcatcacctacgtgattcaggaccccgtgccgcagttccgcattgaccccgac
agtggcaccatgtacaccatgatggagctggactatgagaaccaggtcgcctacacgctg
accatcatggcccaggacaacggcatcccgcagaaatcagacaccaccaccctagagatc
ctcatcctcgatgccaatgacaatgcaccccagttcctgtgggatttctaccagggttcc
atctttgaggatgctccaccctcgaccagcatcctccaggtctctgccacggaccgggac
tcaggtcccaatgggcgtctgctgtacaccttccagggtggggacgacggcgatggggac
ttctacatcgagcccacgtccggtgtgattcgcacccagcgccggctggaccgggagaat
gtggccgtgtacaacctttgggctctggctgtggatcggggcagtcccactccccttagc
gcctcggtagaaatccaggtgaccatcttggacattaatgacaatgcccccatgtttgag
aaggacgaactggagctgtttgttgaggagaacaacccagtggggtcggtggtggcaaag
attcgtgctaacgaccctgatgaaggccctaatgcccagatcatgtatcagattgtggaa
ggggacatgcggcatttcttccagctggacctgctcaacggggacctgcgtgccatggtg
gagctggactttgaggtccggcgggagtatgtgctggtggtgcaggccacgtcggctccg
ctggtgagccgagccacggtgcacatccttctcgtggaccagaatgacaacccgcctgtg
ctgcccgacttccagatcctcttcaacaactatgtcaccaacaagtccaacagtttcccc
accggcgtgatcggctgcatcccggcccatgaccccgacgtgtcagacagcctcaactac
accttcgtgcagggcaacgagctgcgcctgttgctgctggaccccgccacgggcgaactg
cagctcagccgcgacctggacaacaaccggccgctggaggcgctcatggaggtgtctgtg
tctgatggcatccacagcgtcacggccttctgcaccctgcgtgtcaccatcatcacggac
gacatgctgaccaacagcatcactgtccgcctggagaacatgtcccaggagaagttcctg
tccccgctgctggccctcttcgtggagggggtggccgccgtgctgtccaccaccaaggac
gacgtcttcgtcttcaacgtccagaacgacaccgacgtcagctccaacatcctgaacgtg
accttctcggcgctgctgcctggcggcgtccgcggccagttcttcccgtcggaggacctg
caggagcagatctacctgaatcggacgctgctgaccaccatctccacgcagcgcgtgctg
cccttcgacgacaacatctgcctgcgcgagccctgcgagaactacatgaagtgcgtgtcc
gttctgcgattcgacagctccgcgcccttcctcagctccaccaccgtgctcttccggccc
atccaccccatcaacggcctgcgctgccgctgcccgcccggcttcaccggcgactactgc
gagacggagatcgacctctgctactccgacccgtgcggcgccaacggccgctgccgcagc
cgcgagggcggctacacctgcgagtgcttcgaggacttcactggagagcactgtgaggtg
gatgcccgctcaggccgctgtgccaacggggtgtgcaagaacgggggcacctgcgtgaac
ctgctcatcggcggcttccactgcgtgtgtcctcctggcgagtatgagaggccctactgt
gaggtgaccaccaggagcttcccgccccagtccttcgtcaccttccggggcctgagacag
cgcttccacttcaccatctccctcacgtttgccactcaggaaaggaacggcttgcttctc
tacaacggccgcttcaatgagaagcacgacttcatcgccctggagatcgtggacgagcag
gtgcagctcaccttctctgcaggcgagacaacaacgaccgtggcaccgaaggttcccagt
ggtgtgagtgacgggcggtggcactctgtgcaggtgcagtactacaacaagcccaatatt
ggccacctgggcctgccccatgggccgtccggggaaaagatggccgtggtgacagtggat
gattgtgacacaaccatggctgtgcgctttggaaaggacatcgggaactacagctgcgct
gcccagggcactcagaccggctccaagaagtccctggatctgaccggccctctactcctg
gggggtgtccccaacctgccagaagacttcccagtgcacaaccggcagttcgtgggctgc
atgcggaacctgtcagtcgacggcaaaaatgtggacatggccggattcatcgccaacaat
ggcacccgggaaggctgcgctgctcggaggaacttctgcgatgggaggcggtgtcagaat
ggaggcacctgtgtcaacaggtggaatatgtatctgtgtgagtgtccactccgattcggc
gggaagaactgtgagcaagccatgcctcacccccagctcttcagcggtgagagcgtcgtg
tcctggagtgacctgaacatcatcatctctgtgccctggtacctggggctcatgttccgg
acccggaaggaggacagcgttctgatggaggccaccagtggtgggcccaccagctttcgc
ctccagatcctgaacaactacctccagtttgaggtgtcccacggcccctccgatgtggag
tccgtgatgctgtccgggttgcgggtgaccgacggggagtggcaccacctgctgatcgag
ctgaagaatgttaaggaggacagtgagatgaagcacctggtcaccatgaccttggactat
gggatggaccagaacaaggcagatatcgggggcatgcttcccgggctgacggtaaggagc
gtggtggtcggaggcgcctctgaagacaaggtctccgtgcgccgtggattccgaggctgc
atgcagggagtgaggatgggggggacgcccaccaacgtcgccaccctgaacatgaacaac
gcactcaaggtcagggtgaaggacggctgtgatgtggacgacccctgtacctcgagcccc
tgtccccccaatagccgctgccacgacgcctgggaggactacagctgcgtctgtgacaaa
gggtaccttggaataaactgtgtggatgcctgtcacctgaacccctgcgagaacatgggg
gcctgcgtgcgctcccccggctccccgcagggctacgtgtgcgagtgtgggcccagtcac
tacgggccgtactgtgagaacaaactcgaccttccgtgccccagaggctggtgggggaac
cccgtctgtggaccctgccactgtgccgtcagcaaaggctttgatcccgactgtaataag
accaacggccagtgccaatgcaaggagaattactacaagctcctagcccaggacacctgt
ctgccctgcgactgcttcccccatggctcccacagccgcacttgcgacatggccaccggg
cagtgtgcctgcaagcccggcgtcatcggccgccagtgcaaccgctgcgacaacccgttt
gccgaggtcaccacgctcggctgtgaagtgatctacaatggctgtcccaaagcatttgag
gccggcatctggtggccacagaccaagttcgggcagccggctgcggtgccatgccctaag
ggatccgttggaaatgcggtccgacactgcagcggggagaagggctggctgcccccagag
ctctttaactgtaccaccatctccttcgtggacctcagggccatgaatgagaagctgagc
cgcaatgagacgcaggtggacggcgccagggccctgcagctggtgagggcgctgcgcagt
gctacacagcacacgggcacgctctttggcaatgacgtgcgcacggcctaccagctgctg
ggccacgtccttcagcacgagagctggcagcagggcttcgacctggcagccacgcaggac
gccgactttcacgaggacgtcatccactcgggcagcgccctcctggccccagccaccagg
gcggcgtgggagcagatccagcggagcgagggcggcacggcacagctgctccggcgcctc
gagggctacttcagcaacgtggcacgcaacgtgcggcggacgtacctgcggcccttcgtc
atcgtcaccgccaacatgattcttgctgtcgacatctttgacaagttcaactttacggga
gccagggtcccgcgattcgacaccatccatgaagagttccccagggagctggagtcctcc
gtctccttcccagccgacttcttcagaccacctgaagaaaaagaaggccccctgctgagg
ccggctggccggaggaccaccccgcagaccacgcgcccggggcctggcaccgagagggag
gccccgatcagcaggcggaggcgacaccctgatgacgctggccagttcgccgtcgctctg
gtcatcatttaccgcaccctggggcagctcctgcccgagcgctacgaccccgaccgtcgc
agcctccggttgcctcaccggcccatcattaataccccgatggtgagcacgctggtgtac
agcgagggggctccgctcccgagacccctggagaggcccgtcctggtggagttcgccctg
ctggaggtggaggagcgaaccaagcctgtctgcgtgttctggaaccactccctggccgtt
ggtgggacgggagggtggtctgcccggggctgcgagctcctgtccaggaaccggacacat
gtcgcctgccagtgcagccacacagccagctttgcggtgctcatggatatctccaggcgt
gagaacggggaggtcctgcctctgaagattgtcacctatgccgctgtgtccttgtcactg
gcagccctgctggtggccttcgtcctcctgagcctggtccgcatgctgcgctccaacctg
cacagcattcacaagcacctcgccgtggcgctcttcctctctcagctggtgttcgtgatt
gggatcaaccagacggaaaacccgtttctgtgcacagtggttgccatcctcctccactac
atctacatgagcacctttgcctggaccctcgtggagagcctgcatgtctaccgcatgctg
accgaggtgcgcaacatcgacacggggcccatgcggttctactacgtcgtgggctggggc
atcccggccattgtcacaggactggcggtcggcctggacccccagggctacgggaacccc
gacttctgctggctgtcgcttcaagacaccctgatttggagctttgcggggcccatcgga
gctgttataatcatcaacacagtcacttctgtcctatctgcaaaggtttcctgccaaaga
aagcaccattattatgggaaaaaagggatcgtctccctgctgaggaccgcattcctcctg
ctgctgctcatcagcgccacctggctgctggggctgctggctgtgaaccgcgatgcactg
agctttcactacctcttcgccatcttcagcggcttacagggccccttcgtcctccttttc
cactgcgtgctcaaccaggaggtccggaagcacctgaagggcgtgctcggcgggaggaag
ctgcacctggaggactccgccaccaccagggccaccctgctgacgcgctccctcaactgc
aacaccaccttcggtgacgggcctgacatgctgcgcacagacttgggcgagtccaccgcc
tcgctggacagcatcgtcagggatgaagggatccagaagctcggcgtgtcctctgggctg
gtgaggggcagccacggagagccagacgcgtccctcatgcccaggagctgcaaggatccc
cctggccacgattccgactcagatagcgagctgtccctggatgagcagagcagctcttac
gcctcctcacactcgtcagacagcgaggacgatggggtgggagctgaggaaaaatgggac
ccggccaggggcgccgtccacagcacccccaaaggggacgctgtggccaaccacgttccg
gccggctggcccgaccagagcctggctgagagtgacagtgaggaccccagcggcaagccc
cgcctgaaggtggagaccaaggtcagcgtggagctgcaccgcgaggagcagggcagtcac
cgtggagagtaccccccggaccaggagagcgggggcgcagccaggcttgctagcagccag
cccccagagcagaggaaaggcatcttgaaaaataaagtcacctacccgccgccgctgacg
ctgacggagcagacgctgaagggccggctccgggagaagctggccgactgtgagcagagc
cccacatcctcgcgcacgtcttccctgggctctggcggccccgactgcgccatcacagtc
aagagccctgggagggagccggggcgtgaccacctcaacggggtggccatgaatgtgcgc
actgggagcgcccaggccgatggctccgactctgagaaaccgtga

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Ontology (4)   
   KEGG BRITE (4)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (122)   
   KEGG ORTHOLOGY (1)   
   RefGene (114)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (12)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (20)   
   RefSeq(nuc) (10)   
   GenBank (5)   
   EMBL (5)   
3D Structure (2)   
   PDB (2)   
Protein domain (17)   
   Pfam (17)   
All databases (181)   

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