KEGG   Homo sapiens (human): 9711
Entry
9711              CDS       T01001                                 
Symbol
RUBCN, KIAA0226, RUBICON, SCAR15
Name
(RefSeq) rubicon autophagy regulator
  KO
K19330  run domain Beclin-1 interacting and cysteine-rich containing protein
Organism
hsa  Homo sapiens (human)
Pathway
hsa04140  Autophagy - animal
Network
nt06532  Autophagy
  Element
N01718  Autophagy-vesicle nucleation/elongation/maturation, PACER-RUBCN-PI3KC3-C2
Disease
H01891  Autosomal recessive spinocerebellar ataxias
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    9711 (RUBCN)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    9711 (RUBCN)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Other autophagy associated proteins
   Others
    9711 (RUBCN)
SSDB
Motif
Pfam: RUBC_PIKBD RH_dom RUN
Other DBs
NCBI-GeneID: 9711
NCBI-ProteinID: NP_055502
OMIM: 613516
HGNC: 28991
Ensembl: ENSG00000145016
UniProt: Q92622 Q8N4U6
Structure
Position
3:complement(197668867..197749820)
AA seq 972 aa
MRPEGAGMELGGGEERLPEESRREHWQLLGNLKTTVEGLVSTNSPNVWSKYGGLERLCRD
MQSILYHGLIRDQACRRQTDYWQFVKDIRWLSPHSALHVEKFISVHENDQSSADGASERA
VAELWLQHSLQYHCLSAQLRPLLGDRQYIRKFYTDAAFLLSDAHVTAMLQCLEAVEQNNP
RLLAQIDASMFARKHESPLLVTKSQSLTALPSSTYTPPNSYAQHSYFGSFSSLHQSVPNN
GSERRSTSFPLSGPPRKPQESRGHVSPAEDQTIQAPPVSVSALARDSPLTPNEMSSSTLT
SPIEASWVSSQNDSPGDASEGPEYLAIGNLDPRGRTASCQSHSSNAESSSSNLFSSSSSQ
KPDSAASSLGDQEGGGESQLSSVLRRSSFSEGQTLTVTSGAKKSHIRSHSDTSIASRGAP
ESCNDKAKLRGPLPYSGQSSEVSTPSSLYMEYEGGRYLCSGEGMFRRPSEGQSLISYLSE
QDFGSCADLEKENAHFSISESLIAAIELMKCNMMSQCLEEEEVEEEDSDREIQELKQKIR
LRRQQIRTKNLLPMYQEAEHGSFRVTSSSSQFSSRDSAQLSDSGSADEVDEFEIQDADIR
RNTASSSKSFVSSQSFSHCFLHSTSAEAVAMGLLKQFEGMQLPAASELEWLVPEHDAPQK
LLPIPDSLPISPDDGQHADIYKLRIRVRGNLEWAPPRPQIIFNVHPAPTRKIAVAKQNYR
CAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDL
LIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCRLAKELLDSFDTVP
GHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQNEDDI
IFPFELHKCRTCEECKACYHKACFKSGSCPRCERLQARREALARQSLESYLSDYEEEPAE
ALALEAAVLEAT
NT seq 2919 nt   +upstreamnt  +downstreamnt
atgcggccggagggcgcgggaatggagctcggaggcggcgaggagcgcctgcctgaggag
agcaggagggagcactggcagttgctgggtaatttgaagacgacggtggagggtttggta
tcaaccaacagccccaacgtctggtctaagtatggtggcttggagcggctttgcagggac
atgcagagcatcctctatcacgggcttatccgtgaccaggcgtgccgccgccagacggat
tactggcagttcgtgaaagacatccggtggctcagtccccactcagcccttcacgtggag
aagttcatcagcgtgcacgagaacgaccagagcagtgctgatggtgccagtgaacgtgct
gttgccgagctgtggctgcagcacagcctgcagtaccactgcctctcagcccagctccgg
cccctgctcggggatagacagtatatcagaaaattctacacagatgctgccttcctgcta
agtgacgctcatgtcacggccatgctgcagtgcctggaagcagtggaacagaacaacccc
cgcctcctggctcagatcgatgcgtccatgtttgccagaaagcacgagagcccgctcctg
gtgacaaagagccagagcctgacagccctgcccagttccacatacacccctccaaacagc
tatgctcagcattcctactttgggtccttctctagcctccaccaatccgtgcccaacaat
ggctcagagagaagatctacttcctttccactctctggccctccccggaaacctcaagaa
agcagagggcacgtctcaccagcagaggatcaaaccatccaagcccccccagtttcagtc
tctgcactagccagggattcccctttgaccccaaatgaaatgagctccagtactctgacc
agccccatagaggcatcctgggtcagcagccagaatgattccccaggtgatgccagtgag
gggcctgagtacctggccattggcaacttggacccccgaggccggactgccagctgtcag
agtcacagcagcaatgccgagagcagcagttccaatttgttctcctccagcagctcccag
aagccagattctgctgcctcttccttaggggaccaggaaggaggtggggagagccagctg
tccagtgtcctccgcaggtccagcttctcagaggggcagacactcactgtcaccagtggg
gcaaagaaaagccacattcgctcccattcggataccagcattgcctccaggggagctcca
gaatcctgcaatgataaggcgaagttgagaggccctttgccctactctggtcaaagcagt
gaagtcagcacacccagctctctgtacatggaatatgaaggtggtcggtacctgtgctca
ggggaaggcatgttccgaagaccatcagaaggacagtccctcatcagctacctctctgag
caagacttcggcagctgtgccgacctggaaaaggagaatgcccacttcagcatctcagag
tccttaattgctgccatcgagctaatgaagtgcaacatgatgagccagtgcctagaggag
gaggaagtggaagaggaagacagtgatagagagatccaggagctgaagcagaagatccgc
cttcggcgccagcaaatccgcaccaagaacctgctccccatgtaccaggaggctgagcac
ggaagctttcgggtcacctccagcagctcccagttcagctcacgtgattcggcacagctc
tctgactctggctctgctgatgaggttgatgaatttgaaatccaagatgctgacatcaga
aggaacacagcctcaagcagcaaatccttcgtttcctcccagtccttctcccactgcttc
ctgcactccacgtctgctgaggcggtggccatggggctcctgaagcagtttgaggggatg
cagcttccagccgcctcggagctggagtggcttgtcccggagcatgatgcccctcagaag
ctcctgcccattcctgactcactgcccatctcaccggatgacgggcagcacgctgacatc
tacaagctgcggattcgtgttcgtggcaacttggagtgggccccgccccggcctcagata
atttttaatgttcatccagccccaacgaggaaaattgccgtggccaagcagaattaccgc
tgtgcaggatgtggcatccggactgaccctgattacatcaagcgactgcggtactgtgag
tacctgggcaagtacttctgccagtgctgccacgagaatgcccagatggccatccccagc
cgggttctgcgcaagtgggacttcagcaagtactacgtcagcaacttctccaaggacctg
ctcattaagatctggaatgatcctctcttcaacgtgcaggacataaacagtgccctctat
aggaaggtcaagctgctcaatcaagtccggctgctgcgggtccagctgtgtcacatgaag
aacatgttcaagacttgccgactggccaaggagcttctggattcctttgacacagtccca
ggccacctgacagaggacctccacctgtactcactgaatgacctgactgcgaccaggaag
ggggagctggggccccggcttgctgagctcaccagggcaggggctacccatgtggagaga
tgcatgctctgccaagccaaaggcttcatctgtgagttctgtcagaatgaggatgacatc
atctttccctttgagctccataagtgccggacctgtgaagagtgtaaagcgtgttaccat
aaagcctgcttcaagtctggaagctgtccgcgctgcgagcggctgcaggcccggcgggag
gcactggccaggcagagcctggagtcttacctgtcagactacgaggaggagcccgcggaa
gcgctggccctggaagccgccgtcctggaggccacctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (17)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (14)   
DNA sequence (38)   
   RefSeq(nuc) (14)   
   GenBank (12)   
   EMBL (12)   
3D Structure (1)   
   PDB (1)   
Protein domain (3)   
   Pfam (3)   
All databases (88)   

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