KEGG   Homo sapiens (human): 972
Entry
972               CDS       T01001                                 
Symbol
CD74, CLIP, DHLAG, HLADG, II, Ia-GAMMA, p33
Name
(RefSeq) CD74 molecule
  KO
K06505  CD74 antigen
Organism
hsa  Homo sapiens (human)
Pathway
hsa04612  Antigen processing and presentation
hsa05152  Tuberculosis
hsa05168  Herpes simplex virus 1 infection
Network
nt06168  Herpes simplex virus 1 (HSV-1)
  Element
N00590  Antigen processing and presentation by MHC class II molecules
N00591  HSV gB to antigen processing and presentation by MHC class II molecules
Drug target
Milatuzumab: D08944
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    972 (CD74)
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    972 (CD74)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    972 (CD74)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    972 (CD74)
   00535 Proteoglycans [BR:hsa00535]
    972 (CD74)
CD molecules [BR:hsa04090]
 Proteins
  972 (CD74)
Proteoglycans [BR:hsa00535]
 Cell surface proteoglycans
  Others
   972 (CD74)
SSDB
Motif
Pfam: MHC2-interact MHCassoc_trimer Thyroglobulin_1
Other DBs
NCBI-GeneID: 972
NCBI-ProteinID: NP_001020330
OMIM: 142790
HGNC: 1697
Ensembl: ENSG00000019582
UniProt: P04233
Structure
Position
5:complement(150401639..150412910)
AA seq 296 aa
MHRRRSRSCREDQKPVMDDQRDLISNNEQLPMLGRRPGAPESKCSRGALYTGFSILVTLL
LAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRMKLPKPPKPVSKMRMATPLLMQALPM
GALPQGPMQNATKYGNMTEDHVMHLLQNADPLKVYPPLKGSFPENLRHLKNTMETIDWKV
FESWMHHWLLFEMSRHSLEQKPTDAPPKVLTKCQEEVSHIPAVHPGSFRPKCDENGNYLP
LQCYGSIGYCWCVFPNGTEVPNTRSRGHHNCSESLELEDPSSGLGVTKQDLGPVPM
NT seq 891 nt   +upstreamnt  +downstreamnt
atgcacaggaggagaagcaggagctgtcgggaagatcagaagccagtcatggatgaccag
cgcgaccttatctccaacaatgagcaactgcccatgctgggccggcgccctggggccccg
gagagcaagtgcagccgcggagccctgtacacaggcttttccatcctggtgactctgctc
ctcgctggccaggccaccaccgcctacttcctgtaccagcagcagggccggctggacaaa
ctgacagtcacctcccagaacctgcagctggagaacctgcgcatgaagcttcccaagcct
cccaagcctgtgagcaagatgcgcatggccaccccgctgctgatgcaggcgctgcccatg
ggagccctgccccaggggcccatgcagaatgccaccaagtatggcaacatgacagaggac
catgtgatgcacctgctccagaatgctgaccccctgaaggtgtacccgccactgaagggg
agcttcccggagaacctgagacaccttaagaacaccatggagaccatagactggaaggtc
tttgagagctggatgcaccattggctcctgtttgaaatgagcaggcactccttggagcaa
aagcccactgacgctccaccgaaagtactgaccaagtgccaggaagaggtcagccacatc
cctgctgtccacccgggttcattcaggcccaagtgcgacgagaacggcaactatctgcca
ctccagtgctatgggagcatcggctactgctggtgtgtcttccccaacggcacggaggtc
cccaacaccagaagccgcgggcaccataactgcagtgagtcactggaactggaggacccg
tcttctgggctgggtgtgaccaagcaggatctgggcccagtccccatgtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Network (3)   
   KEGG NETWORK (3)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (8)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (34)   
   RefSeq(nuc) (6)   
   GenBank (14)   
   EMBL (14)   
3D Structure (18)   
   PDB (18)   
Protein domain (3)   
   Pfam (3)   
All databases (97)   

Download RDF
DBGET integrated database retrieval system