KEGG   Homo sapiens (human): 9730
Entry
9730              CDS       T01001                                 
Symbol
DCAF1, RIP, VPRBP
Name
(RefSeq) DDB1 and CUL4 associated factor 1
  KO
K11789  DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa05170  Human immunodeficiency virus 1 infection
Network
nt06161  Human immunodeficiency virus 1 (HIV-1)
  Element
N00456  HIV Vpr to CDC25-cell cycle G2M
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    9730 (DCAF1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    9730 (DCAF1)
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    9730 (DCAF1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     9730 (DCAF1)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  Other
   9730 (DCAF1)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul4 complex
    Target recognizing subunit (DCAF)
     9730 (DCAF1)
SSDB
Motif
Pfam: ANAPC4_WD40
Other DBs
NCBI-GeneID: 9730
NCBI-ProteinID: NP_055518
OMIM: 617259
HGNC: 30911
Ensembl: ENSG00000145041
UniProt: Q9Y4B6
Structure
Position
3:complement(51395867..51505639)
AA seq 1507 aa
MTTVVVHVDSKAELTTLLEQWEKEHGSGQDMVPILTRMSQLIEKETEEYRKGDPDPFDDR
HPGRADPECMLGHLLRILFKNDDFMNALVNAYVMTSREPPLNTAACRLLLDIMPGLETAV
VFQEKEGIVENLFKWAREADQPLRTYSTGLLGGAMENQDIAANYRDENSQLVAIVLRRLR
ELQLQEVALRQENKRPSPRKLSSEPLLPLDEEAVDMDYGDMAVDVVDGDQEEASGDMEIS
FHLDSGHKTSSRVNSTTKPEDGGLKKNKSAKQGDRENFRKAKQKLGFSSSDPDRMFVELS
NSSWSEMSPWVIGTNYTLYPMTPAIEQRLILQYLTPLGEYQELLPIFMQLGSRELMMFYI
DLKQTNDVLLTFEALKHLASLLLHNKFATEFVAHGGVQKLLEIPRPSMAATGVSMCLYYL
SYNQDAMERVCMHPHNVLSDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDRY
DGLRRLVNLISTLEILNLEDQGALLSDDEIFASRQTGKHTCMALRKYFEAHLAIKLEQVK
QSLQRTEGGILVHPQPPYKACSYTHEQIVEMMEFLIEYGPAQLYWEPAEVFLKLSCVQLL
LQLISIACNWKTYYARNDTVRFALDVLAILTVVPKIQLQLAESVDVLDEAGSTVSTVGIS
IILGVAEGEFFIHDAEIQKSALQIIINCVCGPDNRISSIGKFISGTPRRKLPQNPKSSEH
TLAKMWNVVQSNNGIKVLLSLLSIKMPITDADQIRALACKALVGLSRSSTVRQIISKLPL
FSSCQIQQLMKEPVLQDKRSDHVKFCKYAAELIERVSGKPLLIGTDVSLARLQKADVVAQ
SRISFPEKELLLLIRNHLISKGLGETATVLTKEADLPMTAASHSSAFTPVTAAASPVSLP
RTPRIANGIATRLGSHAAVGASAPSAPTAHPQPRPPQGPLALPGPSYAGNSPLIGRISFI
RERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCK
NPVATCPPFSLFTPHQCPEPKQRRQAPINFTSRLNRRASFPKYGGVDGGCFDRHLIFSRF
RPISVFREANEDESGFTCCAFSARERFLMLGTCTGQLKLYNVFSGQEEASYNCHNSAITH
LEPSRDGSLLLTSATWSQPLSALWGMKSVFDMKHSFTEDHYVEFSKHSQDRVIGTKGDIA
HIYDIQTGNKLLTLFNPDLANNYKRNCATFNPTDDLVLNDGVLWDVRSAQAIHKFDKFNM
NISGVFHPNGLEVIINTEIWDLRTFHLLHTVPALDQCRVVFNHTGTVMYGAMLQADDEDD
LMEERMKSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGSMDALNM
DTVCRLYEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEED
DNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDD
IILSLNE
NT seq 4524 nt   +upstreamnt  +downstreamnt
atgactacagtagtggtacatgtggactccaaagctgagctcactaccctgctggagcag
tgggaaaaggaacatggcagtgggcaggacatggtacctatccttaccaggatgtctcaa
ttgattgaaaaagaaactgaagagtatcgtaaaggggatccagacccatttgatgatcga
catcctggtcgagctgatccagagtgtatgctgggccacttgctgagaatactcttcaag
aatgatgatttcatgaatgcactggtgaatgcatatgtgatgacaagccgagagccccct
ttaaacactgcagcttgcagactcctattagacatcatgccagggctggaaactgctgtc
gtctttcaagaaaaggagggaattgtcgagaatcttttcaaatgggcccgagaggccgat
caaccattgaggacatattctactggactgttaggaggtgctatggaaaatcaagacatt
gctgccaactatagagatgaaaattcacagctggtggcaatagtgcttcgaagactgagg
gagctacagctacaggaagtggctttgcggcaggaaaacaagcgtcccagtccacggaag
ctctcttctgaaccccttttgcctctggatgaggaggctgtggatatggactatggtgac
atggctgtagatgtagtggatggagaccaagaggaagcttctggagacatggagatctcc
tttcatcttgattcaggccacaagactagtagcagagtgaactcaacaaccaaacctgag
gatggaggattaaagaaaaacaagtcagcaaaacagggtgacagagagaactttaggaaa
gccaagcaaaagttgggtttctcatcttctgatccagatcgcatgtttgttgagctgtct
aatagcagttggtcagaaatgtctccctgggtgattggcaccaattataccctttatcct
atgactcctgctatcgagcagcgactcattctccaatatttgacccctctaggagaatat
caggagctacttcccatattcatgcaacttggatcacgggagctgatgatgttctatatt
gacctgaagcaaactaatgatgtcctgcttacatttgaggcactaaagcacctagcatct
ctcctgctccataacaaatttgccacagaatttgttgcgcatggtggagtacagaaatta
ctggaaatacctcgtccttctatggctgcaaccggtgtgtctatgtgtttgtattaccta
tcctacaatcaggatgccatggaaagagtttgcatgcatccccacaatgttctgtctgat
gtggtgaactataccctgtggttaatggagtgttctcatgcttcaggatgctgccatgct
accatgtttttttcaatttgcttctcatttcgggccgtcttggagctctttgaccgctat
gatggtcttcgtcgtctggtgaacttgatcagtactttggagattctaaatttggaagat
cagggtgcacttctgagtgatgatgaaatatttgctagccgccaaactgggaaacatacc
tgcatggccttgcgcaaatactttgaggctcacctggccattaaattggaacaagtgaag
cagtcacttcagaggactgagggtggcattcttgtccacccacaacccccgtacaaggca
tgctcatatactcatgaacagattgtggaaatgatggaatttttgatagaatatggccca
gcgcagctatattgggaaccagctgaagttttcctcaaactttcttgtgtgcaactcttg
ttgcagcttatttctattgcctgcaattggaagacctattatgcaaggaatgacactgtg
cgctttgctttggatgtcctggctattcttactgtggtgccaaaaatccagctccagttg
gcagaatcagtggacgtgttggatgaggctggatctacagtctctactgtaggtatcagc
attattttgggagtggctgagggtgagttcttcatccatgatgctgaaattcagaagtca
gcacttcagattatcatcaattgtgtgtgtggcccagataaccgaatatccagtattggt
aaatttatctctggtactcctcggagaaagctgcctcagaaccctaaaagcagtgagcac
accctggccaagatgtggaatgtggttcagtccaacaacggcatcaaggtgctcctgtcc
ttactgtccattaagatgcccatcacagatgcagaccaaatccgggccctggcctgcaaa
gccctagtgggcctgtctcgcagtagcactgtccggcagatcatcagtaaactgcccctt
ttcagcagctgccagatccagcagctgatgaaggagcctgtgctgcaggacaagcgcagt
gaccatgtcaagttctgcaagtatgctgctgaactcattgaacgggtgtcaggaaaacca
cttctcattggcactgatgtttccctagcacgactgcagaaagcagatgttgttgcccag
tcaaggatctccttccctgagaaagagctgcttttgttgatacgaaaccatcttatttct
aaagggcttggagaaacagcaaccgtgctgacaaaagaggctgacctgcccatgactgct
gcctcccattcttctgcctttaccccagtcactgctgctgcttctcctgtctctctaccc
cgaacccctcgtatcgctaatggcattgcaactcgtctgggcagccatgctgctgtgggt
gcctctgcgccttctgcccctactgctcatcctcagccacggcccccccagggtccgcta
gctctgcccggcccatcttatgcaggcaactcccctttgattggtagaatcagttttatc
agagagaggccatcaccctgcaatggcaggaaaatcagagtgttgcggcagaagtcggac
catggtgcctacagccaaagcccagccataaaaaaacagctggacagacatcttccttcc
ccacctacgctggacagtataatcacagagtatcttagagaacaacatgctcgctgcaag
aatccagttgccacctgcccacctttctccctctttactcctcaccaatgtcctgagcca
aaacagaggcggcaagcgccaataaactttacgtcaaggctaaaccgcagggcatcattt
ccaaagtatggaggggtggatggcggatgctttgataggcaccttatctttagcagattc
cgtcctatttcagtgttccgggaagccaatgaagatgagagtggcttcacctgctgtgca
ttctcagcacgggagcggttcctgatgcttggcacctgcacagggcagctgaagctctat
aatgtgtttagtggacaggaggaggccagctataactgtcacaactcagccatcacacat
cttgaaccttccagggatgggtccttgctgctgacatctgctacttggagccagcctttg
tctgcactttggggaatgaagtcagtatttgatatgaagcattccttcacagaagatcac
tatgttgagttcagtaagcactcccaggatcgggtcatcggcacaaaaggagacattgcc
cacatttatgatattcagactggcaacaagctgttgactctgtttaacccagatcttgcc
aacaactacaagaggaactgtgccacctttaatcctacagatgatcttgtcttaaatgat
ggcgtcctctgggatgtccgctctgcacaggccatccacaagtttgacaagttcaatatg
aacatcagtggtgttttccatccaaatggactggaggtgatcattaatactgagatttgg
gaccttcgaacttttcatcttttgcatactgttcccgctctggatcagtgtcgcgtggtg
ttcaatcacacgggaacagtgatgtatggagctatgttgcaggcagatgatgaagatgac
ttaatggaagagaggatgaaaagcccctttgggtcatccttccgaacatttaatgcaact
gactacaaacctatagcaaccattgatgtgaaacggaacatctttgacctgtgtacagac
accaaagactgctatcttgctgtcattgagaatcaaggcagcatggatgccctgaacatg
gacacagtatgcaggctgtatgaagtgggcaggcagcgtctggcagaggatgaggatgaa
gaggaggaccaggaagaggaagaacaggaggaagaagatgatgatgaagatgatgatgac
accgatgatttagatgagcttgacactgaccagttgctggaggcggagttggaggaggac
gacaataatgagaacgcaggggaagatggggacaatgacttctctccctctgatgaggag
ctagcaaaccttctagaggagggagaggacggggaggatgaagactctgatgcagatgag
gaggtggaactgatcctgggggacactgacagctctgacaactctgatttggaagatgac
atcatcttatctctgaatgagtga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (55)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (53)   
DNA sequence (89)   
   RefSeq(nuc) (71)   
   GenBank (9)   
   EMBL (9)   
3D Structure (26)   
   PDB (26)   
Protein domain (1)   
   Pfam (1)   
All databases (201)   

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