KEGG   Homo sapiens (human): 9732
Entry
9732              CDS       T01001                                 
Symbol
DOCK4
Name
(RefSeq) dedicator of cytokinesis 4
  KO
K17697  dedicator of cytokinesis protein 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04015  Rap1 signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    9732 (DOCK4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    9732 (DOCK4)
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    9732 (DOCK4)
Membrane trafficking [BR:hsa04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    9732 (DOCK4)
Cilium and associated proteins [BR:hsa03037]
 Primary cilia and associated proteins
  USH complex and associated proteins
   9732 (DOCK4)
SSDB
Motif
Pfam: DOCK_N DOCK-C2 DHR-2_Lobe_C DHR-2_Lobe_B DHR-2_Lobe_A SH3_2 SH3_1
Other DBs
NCBI-GeneID: 9732
NCBI-ProteinID: NP_055520
OMIM: 607679
HGNC: 19192
Ensembl: ENSG00000128512
UniProt: Q8N1I0
Position
7:complement(111726110..112206399)
AA seq 1966 aa
MWIPTEHEKYGVVIASFRGTVPYGLSLEIGDTVQILEKCDGWYRGFALKNPNIKGIFPSS
YVHLKNACVKNKGQFEMVIPTEDSVITEMTSTLRDWGTMWKQLYVRNEGDLFHRLWHIMN
EILDLRRQVLVGHLTHDRMKDVKRHITARLDWGNEQLGLDLVPRKEYAMVDPEDISITEL
YRLMEHRHRKKDTPVQASSHHLFVQMKSLMCSNLGEELEVIFSLFDSKENRPISERFFLR
LNRNGLPKAPDKPERHCSLFVDLGSSELRKDIYITVHIIRIGRMGAGEKKNACSVQYRRP
FGCAVLSIADLLTGETKDDLILKVYMCNTESEWYQIHENIIKKLNARYNLTGSNAGLAVS
LQLLHGDIEQIRREYSSVFSHGVSITRKLGFSNIIMPGEMRNDLYITIERGEFEKGGKSV
ARNVEVTMFIVDSSGQTLKDFISFGSGEPPASEYHSFVLYHNNSPRWSELLKLPIPVDKF
RGAHIRFEFRHCSTKEKGEKKLFGFSFVPLMQEDGRTLPDGTHELIVHKCEENTNLQDTT
RYLKLPFSKGIFLGNNNQAMKATKESFCITSFLCSTKLTQNGDMLDLLKWRTHPDKITGC
LSKLKEIDGSEIVKFLQDTLDTLFGILDENSQKYGSKVFDSLVHIINLLQDSKFHHFKPV
MDTYIESHFAGALAYRDLIKVLKWYVDRITEAERQEHIQEVLKAQEYIFKYIVQSRRLFS
LATGGQNEEEFRCCIQELLMSVRFFLSQESKGSGALSQSQAVFLSSFPAVYSELLKLFDV
REVANLVQDTLGSLPTILHVDDSLQAIKLQCIGKTVESQLYTNPDSRYILLPVVLHHLHI
HLQEQKDLIMCARILSNVFCLIKKNSSEKSVLEEIDVIVASLLDILLRTILEITSRPQPS
SSAMRFQFQDVTGEFVACLLSLLRQMTDRHYQQLLDSFNTKEELRDFLLQIFTVFRILIR
PEMFPKDWTVMRLVANNVIITTVLYLSDALRKNFLNENFDYKIWDSYFYLAVIFINQLCL
QLEMFTPSKKKKVLEKYGDMRVTMGCEIFSMWQNLGEHKLHFIPALIGPFLEVTLIPQPD
LRNVMIPIFHDMMDWEQRRSGNFKQVEAKLIDKLDSLMSEGKGDETYRELFNSILLKKIE
RETWRESGVSLIATVTRLMERLLDYRDCMKMGEVDGKKIGCTVSLLNFYKTELNKEEMYI
RYIHKLYDLHLKAQNFTEAAYTLLLYDELLEWSDRPLREFLTYPMQTEWQRKEHLHLTII
QNFDRGKCWENGIILCRKIAEQYESYYDYRNLSKMRMMEASLYDKIMDQQRLEPEFFRVG
FYGKKFPFFLRNKEFVCRGHDYERLEAFQQRMLNEFPHAIAMQHANQPDETIFQAEAQYL
QIYAVTPIPESQEVLQREGVPDNIKSFYKVNHIWKFRYDRPFHKGTKDKENEFKSLWVER
TSLYLVQSLPGISRWFEVEKREVVEMSPLENAIEVLENKNQQLKTLISQCQTRQMQNINP
LTMCLNGVIDAAVNGGVSRYQEAFFVKEYILSHPEDGEKIARLRELMLEQAQILEFGLAV
HEKFVPQDMRPLHKKLVDQFFVMKSSLGIQEFSACMQASPVHFPNGSPRVCRNSAPASVS
PDGTRVIPRRSPLSYPAVNRYSSSSLSSQASAEVSNITGQSESSDEVFNMQPSPSTSSLS
STHSASPNVTSSAPSSARASPLLSDKHKHSRENSCLSPRERPCSAIYPTPVEPSQRMLFN
HIGDGALPRSDPNLSAPEKAVNPTPSSWSLDSGKEAKNMSDSGKLISPPVPPRPTQTASP
ARHTTSVSPSPAGRSPLKGSVQSFTPSPVEYHSPGLISNSPVLSGSYSSGISSLSRCSTS
ETSGFENQVNEQSAPLPVPVPVPVPSYGGEEPVRKESKTPPPYSVYERTLRRPVPLPHSL
SIPVTSEPPALPPKPLAARSSHLENGARRTDPGPRPRPLPRKVSQL
NT seq 5901 nt   +upstreamnt  +downstreamnt
atgtggatacctacggagcacgagaaatacggcgtggttattgccagtttccgaggaacc
gttccatatggcctgtcattggaaattggagatacagttcagatcctggagaagtgtgat
ggctggtacagaggatttgccttaaaaaacccaaatatcaagggtatatttccttccagc
tacgttcacttgaaaaatgcctgtgtaaagaacaaaggacaatttgaaatggttattccc
actgaagactctgttatcacagaaatgacatcaacattaagagactggggaaccatgtgg
aaacaactctatgtgcgtaatgaaggcgatctcttccaccggctgtggcacatcatgaat
gaaatcctggacctgaggcggcaggtgctggtgggccacctcacccacgaccggatgaag
gacgtgaagcgccacattactgcccggcttgactggggcaatgaacaactgggactggac
ctggtgcctaggaaagagtacgcaatggtggatccggaagacatcagcattactgagctc
taccgattgatggaacatcgacatcggaagaaagacaccccggtgcaggccagcagtcac
cacctctttgtccagatgaagagcctcatgtgttccaacctgggagaggagctggaggtc
atcttctcactctttgacagtaaagagaaccggccaatcagtgagagatttttcttgagg
ctgaatagaaacgggcttcccaaagcccctgataaaccggaacgacattgctccctcttt
gtggatttgggcagcagtgagctaagaaaggacatttatatcaccgtgcacattatccga
atcggtcgaatgggagcaggagaaaaaaagaatgcctgtagtgtccagtaccgacgaccc
tttggctgtgcagttcttagcatcgctgacctgctaacaggagagacaaaggatgacctc
attctgaaagtatacatgtgtaacacagagagtgagtggtaccaaatccatgagaacatc
atcaaaaagctgaatgcacgttataacttgactggctccaatgcaggtttagcagtttcc
ttacagctattgcacggagacattgaacaaatcagaagggaatattcatcagtattttct
catggagtatccataacaaggaagctgggattttcaaatattattatgcctggtgaaatg
aggaatgatttatatatcactattgaaaggggagaatttgagaaaggagggaagagcgtg
gccagaaatgtggaagttacgatgttcattgtagacagtagtggccaaaccctgaaggat
tttatctccttcggctctggggagccaccagccagtgagtaccactcctttgtgctttac
cataacaacagtcccaggtggtctgaactgctgaaacttcccattcctgtggataaattc
cggggtgcacacatccgcttcgagtttcggcattgttccacaaaggagaaaggagagaag
aagttgtttgggttttcttttgtccctctgatgcaagaagatggtaggactcttccagat
ggcactcatgagctcatcgtgcataagtgtgaagaaaacacaaatcttcaggatactacc
cgctacctcaaacttcccttttccaagggcattttccttgggaataataatcaagccatg
aaggccacaaaggagtccttttgtattacatcttttctctgttccacaaaactcacacaa
aatggtgatatgcttgatcttttgaaatggagaacccacccagacaagatcactggctgt
ctctctaaattaaaagaaattgatggctcagagatagtaaagtttctgcaggatacactg
gataccttatttggaattttagatgaaaattcccaaaaatatgggtctaaagtgtttgat
tctttggttcacataataaatttgctgcaagatagcaaatttcatcattttaaacctgta
atggacacttacattgagagtcattttgctggggcacttgcatacagagatctcatcaaa
gtgctcaaatggtacgtggaccggatcacagaagcagagcggcaagagcatatccaggag
gtgctgaaggcacaagaatacatttttaagtatatagttcaatctcgaaggctgttttcc
cttgccactggtgggcaaaacgaagaggagttccgctgctgcattcaggagcttctcatg
tcagtccgtttctttctttcgcaagagagcaaagggtctggagcattatctcagtcacag
gctgtgtttctgagctctttccctgccgtgtactcagaactgttgaagctctttgatgtc
cgggaagtagccaacttggtccaggacaccctgggcagtctgccgaccatcctgcatgtg
gatgattccctgcaggccatcaaactgcagtgcattggcaaaaccgtggaaagccagctt
tataccaacccagattcccgatacattcttctgcctgtcgtgttacatcacctccacatt
cacttgcaagaacagaaggacctgatcatgtgtgcacgtatccttagcaacgtattttgt
cttatcaagaaaaatagctcagaaaaatctgtgctggaggaaatagatgtgatagtggcc
agcttgctggatattctgctgaggaccatattggagatcaccagccgacctcagccatcc
agctcagcaatgcggttccagttccaggatgtcactggggagtttgttgcttgtctcctg
tccctattacgacaaatgacagatagacattatcaacagcttcttgatagttttaataca
aaggaagaactaagggatttcctgctgcagatatttactgtgttccgaatattgatacgc
ccggagatgtttccaaaggactggactgttatgcgcttggttgctaacaatgttattatt
acaacagttctatacctctcagatgcacttcgtaagaacttcttaaatgaaaactttgat
tataagatctgggattcctacttttacctcgcagtcatttttataaaccagttgtgtctg
cagttggagatgttcacaccttccaagaagaaaaaggtgttagaaaagtatggtgacatg
cgggtaacaatgggttgtgaaattttcagcatgtggcaaaacctaggagagcacaagctt
cattttatccctgccctgattggccccttcctagaagtgaccttgataccccagccagat
cttcggaatgtcatgattccaatttttcatgatatgatggactgggagcagaggcggagt
ggcaactttaaacaggtggaagccaagctaattgacaaactggatagcctgatgtcagaa
ggcaaaggtgacgaaacataccgcgagctcttcaacagtattctactaaagaaaattgag
cgggaaacatggcgggaaagtggcgtttcattaattgctactgtaactcgtctaatggag
aggttgttagattacagggactgcatgaaaatgggagaggtagatggcaaaaagattggc
tgcacagttagccttctgaacttctataagactgaactgaacaaggaggagatgtatata
cgctacattcacaaactctatgatctgcatctcaaagcacagaactttacagaagctgca
tataccctcctcttatatgacgagctactggaatggtctgatcggcccctcagggagttc
ctgacctaccccatgcaaacagaatggcagcgcaaagagcacctgcacctcaccatcatc
cagaactttgacagaggcaaatgttgggagaatggcattatcttgtgccggaagattgca
gagcagtatgagagttattatgactacagaaacctgagcaagatgcggatgatggaagcc
tctttgtatgacaaaattatggaccagcaacgtcttgaaccagagttcttcagagttgga
ttttatggaaaaaaatttccatttttcttaagaaataaggagtttgtgtgtcgagggcat
gactacgagaggctggaagccttccaacagagaatgctgaacgagttcccccatgccatc
gccatgcagcacgccaaccagcccgatgagaccatcttccaggcagaagctcagtatttg
cagatatatgctgtgactcccattccagagagccaggaggtcctgcagagagagggtgtt
ccggacaacatcaaaagcttctataaagtgaatcacatctggaaattccgctatgaccga
ccatttcacaaaggcacaaaagataaagagaatgaattcaagagtctctgggtggagaga
acgtcattatacttggtgcagagtttgcctggcatctctcgctggtttgaagtggaaaag
cgtgaagtggtagaaatgagtcctctggaaaatgcaattgaagtgctagaaaataagaat
cagcagctgaagactctgattagtcagtgtcagacaagacagatgcagaatattaatccc
ctgactatgtgcctgaatggagttatagatgctgcagttaatggtggcgtttccaggtat
caagaggcattctttgtcaaagaatatatcttaagtcaccctgaagatggggagaaaatt
gcacgattaagagagctgatgcttgagcaggcacagattctggaatttggtttggccgtg
catgagaagtttgtacctcaagatatgagaccccttcacaaaaagctggttgaccaattc
tttgtgatgaagtcgagcttagggatacaggagttctctgcttgtatgcaagccagtcct
gtccattttcctaatggaagccctcgtgtgtgtagaaactcagcacctgcttctgtgagc
ccagatggtaccagggtaattcctagacgcagcccgttaagttacccagctgtcaaccga
tattcttcctcctcactgtcctcacaagcttctgctgaagtaagcaatattacagggcaa
tcagaaagctctgatgaagtctttaacatgcagccaagtccatctacctcaagcttgagt
tctactcactcggcttcacctaatgtgacaagttctgctccatcgagtgccagagcttct
cctttgttgtctgacaaacacaaacattcccgagaaaactcttgcctgtcaccaagagag
agaccatgcagtgccatctatccaacacctgtggagccttcgcagaggatgctgtttaat
catattggagacggggccttgccacgcagtgacccaaatctctctgcacctgaaaaagct
gtgaaccccacccctagcagctggagcctggacagtgggaaggaagccaagaacatgtcg
gatagtgggaaacttatctctccccctgtccctccaagacccacacagactgcttcacca
gcaagacacacgacatcagtatccccctcgcctgccgggcgatctccattgaagggctct
gtgcagtctttcaccccctctccagtggagtaccactcgccaggactcatctccaactcc
cctgtcttgtcgggcagctacagcagtgggatttcttctctcagccggtgcagcacgtcg
gaaacctcaggctttgaaaatcaggtgaatgaacagtcggcccccctgccggtgccagtg
ccggtgcccgtgccgagctacggcggggaggagccagtgcgcaaggagagcaagactccg
cccccgtacagcgtctacgagcggactctgcggcgccccgtcccgctacctcacagcctc
tccatccccgtcacgtcggagccgcccgcgctgccccccaagcctctggcagcgcgatcc
agccacctggagaatggggcccggaggactgaccccggcccgcggcccaggcccctgccc
cgcaaggtctctcagttataa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (31)   
   KEGG ORTHOLOGY (1)   
   RefGene (25)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (28)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (26)   
DNA sequence (56)   
   RefSeq(nuc) (26)   
   GenBank (15)   
   EMBL (15)   
Protein domain (7)   
   Pfam (7)   
All databases (128)   

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