KEGG   Homo sapiens (human): 9735
Entry
9735              CDS       T01001                                 
Symbol
KNTC1, ROD
Name
(RefSeq) kinetochore associated 1
  KO
K11577  kinetochore-associated protein 1
Organism
hsa  Homo sapiens (human)
Network
nt06515  Regulation of kinetochore-microtubule interactions
  Element
N01534  Dynein recruitment to the kinetochore
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    9735 (KNTC1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Motor proteins
     RZZ complex
      9735 (KNTC1)
SSDB
Motif
Pfam: Rod_C MRP-S22 DUF2240
Other DBs
NCBI-GeneID: 9735
NCBI-ProteinID: NP_055523
OMIM: 607363
HGNC: 17255
Ensembl: ENSG00000184445
UniProt: P50748
Structure
Position
12:122527249..122626396
AA seq 2209 aa
MWNDIELLTNDDTGSGYLSVGSRKEHGTALYQVDLLVKISSEKASLNPKIQACSLSDGFI
IVADQSVILLDSICRSLQLHLVFDTEVDVVGLCQEGKFLLVGERSGNLHLIHVTSKQTLL
TNAFVQKANDENRRTYQNLVIEKDGSNEGTYYMLLLTYSGFFCITNLQLLKIQQAIENVD
FSTAKKLQGQIKSSFISTENYHTLGCLSLVAGDLASEVPVIIGGTGNCAFSKWEPDSSKK
GMTVKNLIDAEIIKGAKKFQLIDNLLFVLDTDNVLSLWDIYTLTPVWNWPSLHVEEFLLT
TEADSPSSVTWQGITNLKLIALTASANKKMKNLMVYSLPTMEILYSLEVSSVSSLVQTGI
STDTIYLLEGVCKNDPKLSEDSVSVLVLRCLTEALPENRLSRLLHKHRFAEAESFAIQFG
LDVELVYKVKSNHILEKLALSSVDASEQTEWQQLVDDAKENLHKIQDDEFVVNYCLKAQW
ITYETTQEMLNYAKTRLLKKEDKTALIYSDGLKEVLRAHAKLTTFYGAFGPEKFSGSSWI
EFLNNEDDLKDIFLQLKEGNLVCAQYLWLRHRANFESRFDVKMLESLLNSMSASVSLQKL
CPWFKNDVIPFVRRTVPEGQIILAKWLEQAARNLELTDKANWPENGLQLAEIFFTAEKTD
ELGLASSWHWISLKDYQNTEEVCQLRTLVNNLRELITLHRKYNCKLALSDFEKENTTTIV
FRMFDKVLAPELIPSILEKFIRVYMREHDLQEEELLLLYIEDLLNRCSSKSTSLFETAWE
AKAMAVIACLSDTDLIFDAVLKIMYAAVVPWSAAVEQLVKQHLEMDHPKVKLLQESYKLM
EMKKLLRGYGIREVNLLNKEIMRVVRYILKQDVPSSLEDALKVAQAFMLSDDEIYSLRII
DLIDREQGEDCLLLLKSLPPAEAEKTAERVIIWARLALQEEPDHSKEGKAWRMSVAKTSV
DILKILCDIQKDNLQKKDECEEMLKLFKEVASLQENFEVFLSFEDYSNSSLVADLREQHI
KAHEVAQAKHKPGSTPEPIAAEVRSPSMESKLHRQALALQMSKQELEAELTLRALKDGNI
KTALKKCSDLFKYHCNADTGKLLFLTCQKLCQMLADNVPVTVPVGLNLPSMIHDLASQAA
TICSPDFLLDALELCKHTLMAVELSRQCQMDDCGILMKASFGTHKDPYEEWSYSDFFSED
GIVLESQMVLPVIYELISSLVPLAESKRYPLESTSLPYCSLNEGDGLVLPVINSISALLQ
NLQESSQWELALRFVVGSFGTCLQHSVSNFMNATLSEKLFGETTLVKSRHVVMELKEKAV
IFIRENATTLLHKVFNCRLVDLDLALGYCTLLPQKDVFENLWKLIDKAWQNYDKILAISL
VGSELASLYQEIEMGLKFRELSTDAQWGIRLGKLGISFQPVFRQHFLTKKDLIKALVENI
DMDTSLILEYCSTFQLDCDAVLQLFIETLLHNTNAGQGQGDASMDSAKRRHPKLLAKALE
MVPLLTSTKDLVISLSGILHKLDPYDYEMIEVVLKVIERADEKITNININQALSILKHLK
SYRRISPPVDLEYQYMLEHVITLPSAAQTRLPFHLIFFGTAQNFWKILSTELSEESFPTL
LLISKLMKFSLDTLYVSTAKHVFEKKLKPKLLKLTQAKSSTLINKEITKITQTIESCLLS
IVNPEWAVAIAISLAQDIPEGSFKISALKFCLYLAERWLQNIPSQDEKREKAEALLKKLH
IQYRRSGTEAVLIAHKLNTEEYLRVIGKPAHLIVSLYEHPSINQRIQNSSGTDYPDIHAA
AKEIAEVNEINLEKVWDMLLEKWLCPSTKPGEKPSELFELQEDEALRRVQYLLLSRPIDY
SSRMLFVFATSTTTTLGMHQLTFAHRTRALQCLFYLADKETIESLFKKPIEEVKSYLRCI
TFLASFETLNIPITYELFCSSPKEGMIKGLWKNHSHESMAVRLVTELCLEYKIYDLQLWN
GLLQKLLGFNMIPYLRKVLKAISSIHSLWQVPYFSKAWQRVIQIPLLSASCPLSPDQLSD
CSESLIAVLECPVSGDLDLIGVARQYIQLELPAFALACLMLMPHSEKRHQQIKNFLGSCD
PQVILKQLEEHMNTGQLAGFSHQIRSLILNNIINKKEFGILAKTKYFQMLKMHAMNTNNI
TELVNYLANDLSLDEASVLITEYSKHCGKPVPPDTAPCEILKMFLSGLS
NT seq 6630 nt   +upstreamnt  +downstreamnt
atgtggaatgatattgagctgctaacaaatgatgataccggaagtgggtacctgagtgtc
ggttcaagaaaagaacatggaactgctttatatcaagtagatttgctagtgaagatctct
tctgaaaaggcctcattaaatccaaagatacaggcatgcagcttaagtgatgggtttatt
attgtagccgaccaatcagtgatattgcttgacagtatttgtagatcacttcaattgcat
cttgtctttgatactgaagtggatgtagttggcctttgtcaagaaggaaagtttcttttg
gttggcgagagaagtggcaacctacatcttattcatgtaacatcaaaacaaacactactc
actaatgcatttgttcagaaagctaacgatgaaaatcggcggacttaccagaatcttgtc
attgagaaggatggttcaaatgaaggtacctattatatgctacttcttacatacagtgga
tttttttgtattacaaaccttcagcttttaaaaattcaacaagcaattgagaatgtagac
ttcagtacagcaaaaaagttacaaggacaaatcaagtccagttttatttctactgaaaat
tatcatactcttggttgtctcagtcttgtggctggagatttagcaagtgaagttcctgtg
ataattgggggaaccggtaattgtgcattctcaaaatgggaaccagattcttccaagaaa
ggaatgacagttaagaaccttattgatgcagagattattaaaggtgcaaagaagttccag
ctgatagacaatctactttttgttcttgatactgataacgtgctgagtttatgggatatt
tacactctaactcctgtatggaactggccctctcttcacgtagaagagtttcttcttact
acagaagcagactctccttcatcagtcacgtggcaaggaattacaaatctcaaattaata
gctctgacagcttcagctaataagaagatgaaaaacctcatggtttattcattacctaca
atggaaatactatattctttggaagtatctagtgtttcttctctggtccaaacaggaatt
agcacagataccatataccttttagaaggagtttgcaaaaatgatccaaaattgtctgaa
gactcagtctctgtgttagtactcagatgtcttacggaagctttaccagaaaacagattg
agtcggttacttcacaaacacagatttgctgaagctgagagttttgccattcagtttgga
ctagatgttgagcttgtttacaaggtcaagtcaaatcatatattggagaaactggcattg
agttctgtggatgccagtgaacagaccgaatggcaacaacttgtagacgacgctaaggaa
aatctacataagatccaggatgatgaatttgtggtgaattactgcctgaaagctcagtgg
ataacctatgaaaccactcaagagatgctgaattatgccaaaaccaggcttttgaagaaa
gaagataaaactgctctcatttattctgatggcttgaaagaggtgctaagagctcatgca
aaattgactactttttatggagcatttggaccagaaaaattcagtggcagttcttggatt
gaatttctaaataatgaagatgatcttaaagatatttttttacagctaaaagaaggaaac
cttgtttgtgcacagtatctttggcttcgacatcgggcaaactttgaaagcagatttgat
gtgaaaatgctggagagcttgctcaactcaatgtctgcatcagtctctttgcaaaagctg
tgtccatggtttaaaaatgatgtgattccatttgtaagaaggactgtgcctgaaggacag
ataattcttgcaaaatggttggaacaagcagccaggaaccttgaattaactgataaggca
aattggccagaaaatggacttcaattggcagagatattttttacagcagaaaaaacagac
gagttgggattggcatcttcctggcattggatttccttgaaagattatcagaacacagag
gaagtatgtcagctaaggactttggtaaataacttgcgagagttgatcacgttgcatagg
aagtacaactgcaaattagccctctctgattttgagaaggaaaatacaaccaccatagtg
ttccgaatgtttgataaagtgctggccccagagcttattccctccatcttagagaagttt
ataagagtttacatgagagaacatgacttgcaagaggaggaacttctcttgctgtacata
gaggatttactgaatagatgcagctcaaagtccacatcactctttgaaacagcatgggaa
gcaaaggccatggcagtaatagcgtgtttatctgacacggacctcatatttgatgccgtg
ctcaagatcatgtatgcggcagtggttccttggagtgcagctgtggagcaactggtgaaa
cagcacctggaaatggaccatcccaaagtcaagttattacaggaaagttacaaactaatg
gagatgaaaaaacttttacgaggctatggaataagagaggtaaatctcttaaacaaggaa
ataatgagagtggttagatacattctcaaacaagatgtcccatcttctttagaagatgct
ttaaaggtagcccaagcgtttatgttatctgatgatgagatctacagtctaagaattatt
gacctgattgatagagaacagggtgaagactgtctccttctgttgaagtctttgcctcct
gctgaagctgagaaaactgcagaaagagtcatcatatgggcacgactggcattacaagaa
gagccagatcattctaaagagggcaaggcctggagaatgtctgtagcgaagacatccgtg
gacattcttaagatactatgtgacattcagaaagacaatctgcagaagaaggacgaatgt
gaagaaatgttgaaactatttaaagaggttgctagcttacaggagaactttgaggtcttt
ctttcatttgaagattatagcaatagttccctggtagcagatctccgtgagcagcacatt
aaagctcacgaagttgcacaggcgaaacacaaacctgggagcaccccagagcccatagct
gctgaggtgaggagcccaagcatggaatcaaagctgcacagacaggcactggccctgcag
atgtccaaacaagagctggaggcagagctgaccttgagagccttaaaagatgggaacatc
aaaacagcactgaaaaaatgcagcgacttgtttaagtatcactgcaatgctgacactggg
aaattgctatttctgacatgtcagaagctttgtcagatgttggctgataatgtcccagtg
acagtgcctgtgggactgaatcttccttccatgatacatgatctagcaagccaagctgcc
accatttgcagtccagattttttactagatgctttagaactatgtaaacatactttaatg
gctgtagagctttccagacaatgccaaatggatgactgtggaatcctcatgaaagcttct
tttgggacacataaagatccatatgaagagtggtcttacagtgacttcttcagtgaagat
ggaattgttcttgagtcacagatggtgcttccagtgatttatgaactgatttcatctctt
gtgcctctagctgaaagcaagagatatcccttggagtctaccagtttgccatactgctcc
cttaatgaaggagatggccttgttttacctgttataaattccatctctgccctgcttcag
aatcttcaggaatctagccagtgggagctagccctaagatttgtggttggttcatttggt
acctgtcttcagcactctgtgtcaaacttcatgaatgccactttgagtgaaaagttattt
ggagagactacattagttaaatcaaggcatgttgttatggaattgaaagaaaaagctgtt
atatttatcagggaaaatgctacaacactactgcacaaagtatttaattgtcgcttggta
gatcttgacctggcgttgggttactgcactctcttacctcaaaaagatgtgtttgaaaat
ctctggaagctcatagataaagcatggcagaattacgacaaaatcttggcaatatctctg
gtgggctctgagctggcaagtctctatcaggaaatagaaatggggcttaagttccgtgaa
ctcagtactgatgcccagtggggcattcgtcttggtaaacttggtatttcttttcaacca
gttttcaggcaacattttctcaccaagaaagacctcattaaagctcttgtggagaatata
gatatggacacaagcctcattttggaatattgcagcacatttcagttggactgcgatgca
gttcttcagctcttcattgaaacgctgctccacaacacaaatgccggccaaggccaggga
gatgcaagcatggactctgcaaagcggcggcatcccaaactcctggccaaagcccttgag
atggttcctttactgacgagcacaaaagatttggtcatcagtcttagtggaatactacat
aagttggatccttatgactatgaaatgattgaagttgtcttgaaagttatagaacgagct
gatgaaaagataaccaatattaatattaatcaggcattgagtattctgaaacatttgaag
tcatacagaagaatttctcctcccgtggatctagaatatcagtatatgttggaacatgtc
ataactttgccatcagctgcccaaactagactgccttttcacctgatattctttggcaca
gcacagaacttctggaaaattctctctacagaactcagtgaagaatctttcccaacattg
ctcttaatttcgaaattaatgaagttctctctggacactctgtacgtgtctacagcaaaa
cacgttttcgaaaaaaaactgaagccaaagctcctgaagttaacacaagctaaatcctca
acactgattaacaaggaaataactaagatcacgcagaccatcgaatcctgcttactctct
atagtcaacccagagtgggctgtagctattgccatcagccttgcccaggatatccctgaa
ggttccttcaagatatctgctttgaaattctgcctttatttagctgagagatggctacag
aatatcccatcgcaggacgaaaaacgtgaaaaagccgaggctttgttgaagaagcttcat
atccagtaccggcgatcgggcacagaagctgtgctcatagcccacaagctgaacactgag
gaatatttaagagtgatcggaaagccagcacatcttattgtcagtctctacgaacatcct
agcatcaatcaaagaattcagaattcatctggcacagattatcctgatattcatgcagca
gctaaagaaatagccgaagtcaatgaaattaatttggaaaaagtctgggacatgttgttg
gaaaaatggctatgcccttcaacaaaacctggtgaaaaaccatcagaattatttgaactt
caagaagatgaagccctacgaagagtgcagtatctcctcctgtctcgtccaattgattat
agttcaagaatgctgtttgtatttgcaacatcaactacaaccacattaggtatgcatcag
ttaacttttgcccatagaactcgagctcttcagtgtctcttctatttggctgacaaggaa
actatagaatctctctttaaaaaacccattgaagaagtgaaatcttatttgagatgtata
acttttctggcatcatttgagactttgaatatccccatcacatatgaattattttgcagc
agtcctaaagaaggaatgattaagggtctgtggaaaaaccacagccacgagtccatggca
gtaagattggtgactgagctgtgtttagaatacaaaatctatgacctgcagctttggaat
ggactcttgcaaaagcttctgggcttcaatatgattccttatctaaggaaagttttaaaa
gccatctccagtatccattctttatggcaggttccctacttcagcaaagcgtggcagcgt
gtgatacagataccactgctttcagcctcttgtcctttaagtcctgatcagctgtcagat
tgttctgagagtctcatcgctgtcctcgaatgtccagtctcaggtgatcttgacctgatc
ggagtcgccaggcagtatatccagttagaacttccggcttttgcattagcttgtctgatg
ctcatgccccactcagagaaaagacaccagcaaattaagaattttctgggttcctgtgac
cctcaggttattttaaagcaattggaagagcatatgaacacgggccagctagcaggattt
tcacatcaaattagaagtctgattttgaataatatcatcaataagaaggagtttgggatt
ttggcaaagaccaaatactttcaaatgttgaagatgcatgcgatgaataccaacaatatc
actgagctagtgaactatttggcaaatgacttaagtttagatgaagcttcagtcttgata
actgaatattcaaagcactgcgggaaacctgtgcctccagacactgctccctgtgaaatt
ctgaagatgtttcttagtggattatcgtaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (23)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (21)   
DNA sequence (38)   
   RefSeq(nuc) (22)   
   GenBank (8)   
   EMBL (8)   
3D Structure (1)   
   PDB (1)   
Protein domain (3)   
   Pfam (3)   
All databases (91)   

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