KEGG   Homo sapiens (human): 9820
Entry
9820              CDS       T01001                                 
Symbol
CUL7, 3M1, CUL-7, KIAA0076, dJ20C7.5
Name
(RefSeq) cullin 7
  KO
K10613  cullin 7
Organism
hsa  Homo sapiens (human)
Pathway
hsa04120  Ubiquitin mediated proteolysis
Disease
H00509  3M syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    9820 (CUL7)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    9820 (CUL7)
   03036 Chromosome and associated proteins [BR:hsa03036]
    9820 (CUL7)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul7 complex
    Cullin
     9820 (CUL7)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   3M complex
    9820 (CUL7)
SSDB
Motif
Pfam: Cul7 Cullin ANAPC10 HEAT_2 Cullin_Nedd8 F5_F8_type_C
Other DBs
NCBI-GeneID: 9820
NCBI-ProteinID: NP_055595
OMIM: 609577
HGNC: 21024
Ensembl: ENSG00000044090
UniProt: Q14999
Structure
Position
6:complement(43037617..43053851)
AA seq 1698 aa
MVGELRYREFRVPLGPGLHAYPDELIRQRVGHDGHPEYQIRWLILRRGDEGDGGSGQVDC
KAEHILLWMSKDEIYANCHKMLGEDGQVIGPSQESAGEVGALDKSVLEEMETDVKSLIQR
ALRQLEECVGTIPPAPLLHTVHVLSAYASIEPLTGVFKDPRVLDLLMHMLSSPDYQIRWS
AGRMIQALSSHDAGTRTQILLSLSQQEAIEKHLDFDSRCALLALFAQATLSEHPMSFEGI
QLPQVPGRVLFSLVKRYLHVTSLLDQLNDSAAEPGAQNTSAPEELSGERGQLELEFSMAM
GTLISELVQAMRWDQASDRPRSSARSPGSIFQPQLADVSPGLPAAQAQPSFRRSRRFRPR
SEFASGNTYALYVRDTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGVPPVQVFWESTGRT
YWVHWHMLEILGFEEDIEDMVEADEYQGAVASRVLGRALPAWRWRPMTELYAVPYVLPED
EDTEECEHLTLAEWWELLFFIKKLDGPDHQEVLQILQENLDGEILDDEILAELAVPIELA
QDLLLTLPQRLNDSALRDLINCHVYKKYGPEALAGNQAYPSLLEAQEDVLLLDAQAQAKD
SEDAAKVEAKEPPSQSPNTPLQRLVEGYGPAGKILLDLEQALSSEGTQENKVKPLLLQLQ
RQPQPFLALMQSLDTPETNRTLHLTVLRILKQLVDFPEALLLPWHEAVDACMACLRSPNT
DREVLQELIFFLHRLTSVSRDYAVVLNQLGARDAISKALEKHLGKLELAQELRDMVFKCE
KHAHLYRKLITNILGGCIQMVLGQIEDHRRTHQPINIPFFDVFLRYLCQGSSVEVKEDKC
WEKVEVSSNPHRASKLTDHNPKTYWESNGSAGSHYITLHMRRGILIRQLTLLVASEDSSY
MPARVVVCGGDSTSSLHTELNSVNVMPSASRVILLENLTRFWPIIQIRIKRCQQGGIDTR
IRGLEILGPKPTFWPVFREQLCRHTRLFYMVRAQAWSQDMAEDRRSLLHLSSRLNGALRQ
EQNFADRFLPDDEAAQALGKTCWEALVSPVVQNITSPDEDGISPLGWLLDQYLECQEAVF
NPQSRGPAFFSRVRRLTHLLVHVEPCEAPPPVVATPRPKGRNRSHDWSSLATRGLPSSIM
RNLTRCWRAVVEKQVNNFLTSSWRDDDFVPRYCEHFNILQNSSSELFGPRAAFLLALQNG
CAGALLKLPFLKAAHVSEQFARHIDQQIQGSRIGGAQEMERLAQLQQCLQAVLIFSGLEI
ATTFEHYYQHYMADRLLGVVSSWLEGAVLEQIGPCFPNRLPQQMLQSLSTSKELQRQFHV
YQLQQLDQELLKLEDTEKKIQVGLGASGKEHKSEKEEEAGAAAVVDVAEGEEEEEENEDL
YYEGAMPEVSVLVLSRHSWPVASICHTLNPRTCLPSYLRGTLNRYSNFYNKSQSHPALER
GSQRRLQWTWLGWAELQFGNQTLHVSTVQMWLLLYLNDLKAVSVESLLAFSGLSADMLNQ
AIGPLTSSRGPLDLHEQKDIPGGVLKIRDGSKEPRSRWDIVRLIPPQTYLQAEGEDGQNL
EKRRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPRGLVSSLGKGSACSSTD
VLSCILHLLGKGTLRRHDDRPQVLSYAVPVTVMEPHTESLNPGSSGPNPPLTFHTLQIRS
RGVPYASCTATQSFSTFR
NT seq 5097 nt   +upstreamnt  +downstreamnt
atggtgggagaactccgctacagggaattcagggtgcccctggggcccggcttacatgcc
tatcctgatgagctgatccgccagcgcgtgggccatgatgggcatcctgagtaccagatc
cgttggctcatcctgcggcgtggcgatgagggggacgggggctctggccaagtggactgc
aaggctgagcacatcctgctgtggatgtccaaggatgagatctatgccaactgccacaag
atgctgggcgaggatggccaggtcatcgggccctcccaggagtctgcaggggaggttggg
gccctggacaaatctgtgctggaggagatggaaaccgacgtgaagtccctcattcagaga
gcccttcggcagctggaggagtgtgtgggcactatccctcctgctcctctacttcacact
gtccacgtgctcagcgcctatgccagcattgagcccctcactggagtattcaaggaccca
agggtcctggacttgctcatgcacatgttgagtagtcctgattatcagattcgctggagt
gcaggccggatgatacaagccctgtcctcccatgacgctgggacccggactcagatcctt
ctgtcactgagccaacaagaagccattgagaaacacctggattttgacagccgctgtgct
ctgctagcactgtttgcacaggccacgctctctgaacaccccatgtctttcgagggcatt
cagctaccacaggtcccaggaagggtgctcttctccctggtgaagcggtatttgcatgtc
acctcgctcctggatcagctgaacgacagtgctgcggagccaggagcccagaacacctct
gctcctgaggagttgagtggggagaggggtcaactggagctggagttcagtatggccatg
ggcaccctgatctcggagctggtgcaagccatgcgctgggaccaggcctcagacagacca
aggagctcagcacggtcccccggttccatcttccagcctcagctggcagatgtgagccca
gggctccccgctgcccaggctcagccctccttcaggaggtcaagacgttttcgccctcgt
tctgagttcgcaagtggcaatacctatgctttgtatgtgcgggacacactgcagccgggg
atgcgagtgcggatgctggatgattatgaggagatcagtgccggggatgagggcgagttt
cggcagagcaacaacggtgtgcctcctgtgcaggtattttgggagtcaacaggccgcacc
tattgggtgcactggcacatgctggagatcttgggctttgaggaagacattgaggacatg
gttgaggctgatgagtaccaaggggcagtggccagtagagtcctgggtagagccctgcct
gcctggcgctggaggcccatgacagaactctatgctgtgccttatgtgctgcctgaggat
gaggacactgaggagtgtgaacacctgaccctggctgagtggtgggaactcctcttcttc
atcaagaagctggatggacctgaccatcaggaggttctccagatcctccaggagaaccta
gatggggagattctggatgatgagatcctagctgaactggccgtgcccatagaattggcc
caggacttgctgctgactctgccacagcgactcaatgacagtgccctcagggacctgatc
aactgccatgtctacaagaagtatgggcctgaagccctagcagggaaccaagcctaccca
tcccttctagaagcccaagaagatgtcctcctgctagacgcgcaggcccaggctaaggac
tcagaagatgcagccaaagtggaagcaaaagaacccccatctcagagtcccaacactccc
ctgcagcgtctggtggagggttatggtccagctgggaaaatcctcctggatctagagcaa
gccctcagctcagaggggacccaggagaacaaggtcaagccactcctgctgcagctgcag
cggcagccgcagcccttcctggcactgatgcagagcctggacactccggagactaacagg
accctgcacctgactgtgctgagaatcctgaagcagctggtggacttccccgaggcactg
ctgctcccctggcacgaggccgtggatgcctgcatggcctgcctgcggtccccaaacact
gatcgagaggtgctccaggaactgattttcttcctgcaccgcctgacctcagtgagcagg
gactatgccgtggtgctgaatcagctgggagcaagagacgctatctccaaggccctggaa
aagcacctgggaaagctggagctggctcaggagctgcgggacatggtgttcaagtgtgag
aagcatgcccacctctaccgcaaactcatcaccaacatcctgggaggctgcatccagatg
gtgctgggccagatcgaagaccacagacgaacccaccaacccatcaacatccctttcttt
gatgtgttcctcagatacctgtgccagggctccagtgtggaagtgaaggaggacaagtgc
tgggagaaggtggaggtgtcctccaacccgcaccgggccagcaagctgacggaccacaac
cccaagacctattgggagtccaacggcagcgccggctcccactacatcaccctgcacatg
cgccggggcatcctcatcaggcaactgactctgcttgtggctagtgaggactcgagttac
atgccggcccgagtggtggtgtgcgggggtgatagcactagctctcttcacacggaactc
aactcggtgaatgtgatgccctctgccagccgggtgatcctcctggagaacctgacccgc
ttctggcccatcatccagatccgcataaagcgctgccagcagggtggcattgatacgcgc
attcgggggttagagatcctaggccccaagcccacgttctggccagtgttccgggagcag
ctctgtcgtcacacacgcctcttctacatggttcgggcacaggcctggagccaggacatg
gcagaggaccgcaggagcctcctgcacctgagttctagactcaacggtgctctgcgccag
gagcagaattttgctgaccgcttcctccctgatgacgaggctgcccaagctctgggcaag
acctgctgggaggccctggtcagccccgtggtgcagaacatcacctcccctgatgaggat
ggcattagccccctgggttggctgctggaccagtacctggagtgtcaggaagctgtcttc
aacccccagagccgcggcccagctttcttctcgcgggtgcgccgtctcactcacctgctg
gtgcatgtcgagccctgtgaggcaccccctcctgtggtggccactcctcggcccaaaggc
agaaacagaagccacgactggagctccttggctacccggggccttccaagcagcatcatg
agaaacctgacgcgctgttggcgggccgtggtggagaagcaggtgaacaattttctgacc
tcatcctggcgggatgatgactttgtgccacgctactgtgagcactttaatattctgcag
aactcaagctctgaactgtttgggcctcgggcagccttcttgctggcgctgcaaaatggc
tgtgcgggagccttgctgaagctcccttttctcaaagctgcccacgtgagtgagcagttc
gcccggcacattgaccagcagatccagggcagccggatcggtggagcccaggaaatggag
aggctggcacagctgcagcaatgcctgcaagctgtcctgattttctccggcttggagata
gccaccacttttgagcattattaccagcactacatggcggaccgtctcctgggcgtggtc
tcgagctggctggagggggccgtgctggagcagatcggtccctgcttccccaaccgcctc
ccccagcagatgttgcagagcctgagcacctctaaggagctgcagcgccagttccacgtc
taccagctccagcagctggatcaggaactcctgaagctggaggatacagagaagaaaata
caggtgggccttggggccagtggcaaggagcacaagagcgagaaggaagaggaagctggg
gcagcagcagtggtggatgtggcggagggagaggaggaagaggaggagaatgaggacctc
tactatgaaggggcaatgccagaagtgtctgtgcttgtcctgtcccgacactcctggcct
gttgcctcaatctgccacacactgaaccccagaacctgcctgccctcctacctgaggggc
actttgaacagatactccaacttctacaacaagagtcagagccaccctgcccttgagcga
ggctcacagaggcgactgcagtggacgtggctgggctgggctgagctgcagtttgggaac
cagaccctgcatgtgtccaccgtgcagatgtggctactgctgtatctcaacgacctgaag
gcggtctctgtggagagtctgctggcgttctcagggctctccgcagacatgctcaatcag
gcgattgggcccctcacctcttcaagaggccccctggaccttcacgagcaaaaggatata
ccaggaggggtcctcaagattcgagatggcagcaaggaacccaggtcgagatgggacatt
gtgcggctcatcccacctcagacgtacctgcaagctgagggtgaagacggccagaacttg
gagaagagacggaatcttctgaactgcctcatcgtccgaatcctcaaggcccatggagat
gaggggctgcacattgaccagcttgtctgtctggtgctggaggcttggcagaagggcccg
tgtcctcccaggggtttggtcagcagccttggtaaggggtctgcatgcagcagcactgac
gtcctctcctgcatcctacacctcctgggcaagggcacgctgagacgccatgacgaccgg
ccccaggtgctgtcctatgcagtccctgtgactgtcatggagcctcacactgagtccctg
aacccaggctcctcaggccccaacccacccctcaccttccataccctacagattcgctcc
cggggtgtgccctatgcctcctgcactgccacccagagcttctctaccttccggtag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (42)   
   KEGG ORTHOLOGY (1)   
   RefGene (23)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (13)   
   OC (1)   
Protein sequence (25)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (23)   
DNA sequence (39)   
   RefSeq(nuc) (23)   
   GenBank (8)   
   EMBL (8)   
3D Structure (2)   
   PDB (2)   
Protein domain (6)   
   Pfam (6)   
All databases (122)   

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