KEGG   Homo sapiens (human): 9844
Entry
9844              CDS       T01001                                 
Symbol
ELMO1, CED-12, CED12, ELMO-1
Name
(RefSeq) engulfment and cell motility 1
  KO
K12366  engulfment and cell motility protein 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04062  Chemokine signaling pathway
hsa04148  Efferocytosis
hsa05100  Bacterial invasion of epithelial cells
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05135  Yersinia infection
Network
nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06182  Shigella
nt06183  Yersinia
nt06535  Efferocytosis
  Element
N00951  ITGA/B-RHOG-RAC signaling pathway
N00952  Shigella IpgB1 to ITGA/B-RHOG-RAC signaling pathway
N01068  ITGA/B-FAK-RAC signaling pathway
N01132  Salmonella SopE/E2 to RhoG signaling pathway
N01133  Salmonella SopB to RhoG signaling pathway
N01761  Activation of CRK-DOCK-Rac1 pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    9844 (ELMO1)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    9844 (ELMO1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    9844 (ELMO1)
   05131 Shigellosis
    9844 (ELMO1)
   05135 Yersinia infection
    9844 (ELMO1)
   05100 Bacterial invasion of epithelial cells
    9844 (ELMO1)
SSDB
Motif
Pfam: ELMO_ARM ELMO_CED12 PH_12 FERM_N
Other DBs
NCBI-GeneID: 9844
NCBI-ProteinID: NP_001193409
OMIM: 606420
HGNC: 16286
Ensembl: ENSG00000155849
UniProt: Q92556 A4D1X5
Structure
Position
7:complement(36852906..37449326)
AA seq 727 aa
MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFY
ITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEF
INLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAF
IKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQ
TYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVL
TFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKSMYTRDYKKLG
FINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIEL
TKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKV
MQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKI
QPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP
HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKH
EYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNY
DFVYDCN
NT seq 2184 nt   +upstreamnt  +downstreamnt
atgccgccacccgcggacatcgtcaaggtggccatagaatggccgggcgcctaccccaaa
ctcatggaaattgatcagaaaaaaccactgtctgcaataataaaggaagtctgtgatggg
tggtctcttgccaaccatgaatattttgcactccagcatgccgatagttcaaacttctat
atcacagaaaagaaccgcaatgagataaaaaatggcactatccttcgattaaccacatct
ccagctcagaacgcccagcagctccatgaacgaatccagtcctcgagtatggatgccaag
ctggaagccctgaaggacttggccagcctctcccgggatgtcacgtttgcccaggagttt
ataaacctggacggtatctctctcctcacgcagatggtggagagcggcactgagcgatac
cagaaattgcagaagatcatgaagccttgctttggagacatgctgtccttcaccctgacg
gccttcgttgagctgatggaccatggcatagtgtcctgggatacattttcggtggcgttc
attaagaagatagcaagttttgtgaacaagtcagccatagacatctcgatcctgcagcgg
tccttggccattttggagtcgatggtgctcaatagccatgacctctaccagaaagtggcg
caggagatcaccatcggccagctcattccacacctgcaagggtcagatcaagaaatccaa
acctatactattgcagtgattaatgcgcttttcctgaaggctcctgatgagaggaggcag
gagatggcgaatattttggctcagaagcaactgcgttccatcattttaacacatgtcatc
cgagcccagcgggccatcaacaatgagatggcgcaccagctgtatgttctacaagtgctc
acctttaacctcctggaagacaggatgatgaccaaaatggacccccaggaccaggctcag
agggacatcatatttgaacttcgaagaattgcttttgatgctgagtctgaacctaacaac
agcagtggcagcatggagaaacgcaagtccatgtacacgcgagattataagaagcttggg
ttcattaatcatgtcaaccctgccatggacttcacgcagactccacctgggatgttggct
ctggacaacatgctgtactttgccaagcaccaccaagatgcctacatccggattgtgctt
gagaacagtagtcgagaagacaagcatgaatgtccctttggccgcagtagtatagagctg
accaagatgctatgtgagatcttgaaagtgggcgagttgcctagtgagacctgcaacgac
ttccacccgatgttcttcacccacgacagatcctttgaggagtttttctgcatctgtatc
cagctcctgaacaagacatggaaggaaatgagggcaacttctgaagacttcaacaaggta
atgcaggtggtgaaggagcaggttatgagagcacttacaaccaagcctagctccctggac
cagttcaagagcaaactgcagaacctgagctacactgagatcctgaaaatccgccagtcc
gagaggatgaaccaggaagatttccagtcccgcccgattttggaactaaaggagaagatt
cagccagaaatcttagagctgatcaaacagcaacgcctgaaccgccttgtggaagggacc
tgctttaggaaactcaatgcccggcggaggcaagacaagttttggtattgtcggctttcg
ccaaatcacaaagtcctgcattacggagacttagaagagagtcctcagggagaagtgccc
cacgattccttgcaggacaaactgccggtggcagatatcaaagccgtggtgacgggaaag
gactgccctcatatgaaagagaaaggtgcccttaaacaaaacaaggaggtgcttgaactc
gctttctccatcttgtatgactcaaactgccaactgaacttcatcgctcctgacaagcat
gagtactgtatctggacggatggactgaatgcgctactcgggaaggacatgatgagcgac
ctgacgcggaatgacctggacaccctgctcagcatggaaatcaagctccgcctcctggac
ctggaaaacatccagatccctgacgcacctccgccgattcccaaggagcccagcaactat
gacttcgtctatgactgtaactga

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (6)   
   KEGG PATHWAY (6)   
Network (11)   
   KEGG NETWORK (11)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (30)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (27)   
DNA sequence (64)   
   RefSeq(nuc) (28)   
   GenBank (18)   
   EMBL (18)   
3D Structure (8)   
   PDB (8)   
Protein domain (4)   
   Pfam (4)   
All databases (134)   

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