KEGG   Homo sapiens (human): 9887
Entry
9887              CDS       T01001                                 
Symbol
SMG7, C1orf16, EST1C, SGA56M
Name
(RefSeq) SMG7 nonsense mediated mRNA decay factor
  KO
K14409  protein SMG7
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    9887 (SMG7)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    9887 (SMG7)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Surveillance factors
    Other surveillance factors
     9887 (SMG7)
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     9887 (SMG7)
SSDB
Motif
Pfam: EST1_DNA_bind EST1 TPR_17 TPR_2 TPR_7
Other DBs
NCBI-GeneID: 9887
NCBI-ProteinID: NP_775179
OMIM: 610964
HGNC: 16792
Ensembl: ENSG00000116698
UniProt: Q92540 Q6TV06
Structure
Position
1:183472499..183554191
AA seq 1137 aa
MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDL
WNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCR
VKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQ
LVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEV
KTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVI
NLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYP
LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFE
LQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEV
GKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTG
EKPVVTFKENIKTREVNRDQGRSFPPKEVRRDYSKGITVTKNDGKKDNNKRKTETKKCTL
EKLQETGKQNVAVQVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPS
RPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQ
QRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK
SPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVM
QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGV
FRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTS
SSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHN
HNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGT
WTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH
NT seq 3414 nt   +upstreamnt  +downstreamnt
atgagcctgcagagcgcgcagtacctccggcaggcagaagtcctgaaggctgacatgaca
gattctaagctgggtccagctgaagtctggacatccaggcaggctctgcaggacctgtac
cagaaaatgctagttaccgatttggaatacgctttagacaagaaagtagaacaggatctc
tggaatcacgcctttaagaatcagatcacaacactgcaaggccaggcaaagaatcgagca
aatccgaatcggagtgaagttcaggcaaacctttctctgttcctagaggcagctagtggc
ttctatactcagttattacaagaactgtgtacagtatttaatgtagatttaccatgccgt
gtgaagtcttcccaattgggaattatcagcaataaacagacgcataccagcgccatagtg
aagccacagtctagctcctgttcctatatctgccagcactgcctcgtccaccttggagac
attgctcgatacagaaaccagaccagccaggcagagtcctactataggcatgcagctcag
cttgtcccctccaatggtcagccttataatcagttggctatcttagcttcttccaaagga
gaccatctgaccacaattttctactactgcagaagcattgctgtgaagttccctttccca
gctgcctccactaatctgcaaaaagcactttctaaagcactggaaagccgagatgaggtg
aaaaccaagtggggtgtttctgacttcatcaaggcctttattaaattccacggtcatgtg
tacctgagtaagagcttggaaaagttgagccctcttcgagagaaattggaagaacagttt
aagaggctgctattccaaaaagctttcaactctcagcagttagttcatgtcactgtcatt
aacctgtttcaacttcatcaccttcgtgactttagcaatgaaaccgagcagcacacttat
agccaagatgagcagctatgttggacacagttgctggccctctttatgtcttttcttggc
atcctgtgcaagtgtcctctacagaatgagtctcaggaggagtcctacaatgcctatcct
cttccagcagtcaaggtctccatggactggctaagactcagacccagggtctttcaggag
gcagtggtggatgaaagacagtacatttggccctggttgatttctcttctgaatagtttc
catccccatgaagaggacctctcaagtattagtgcgacaccacttccagaggagtttgaa
ttacaaggatttttggcattgagaccttctttcaggaacttggatttttccaaaggtcac
cagggtattacaggggacaaagaaggccagcaacgacgaatacgacagcaacgcttgatc
tctataggcaaatggattgctgataatcagccaaggctgattcagtgtgaaaatgaggta
gggaaattgttgtttatcacagaaatcccagaattaatactggaagaccccagtgaagcc
aaagagaacctcattctgcaagaaacatctgtgatagagtcgctggctgcagatgggagc
ccagggctaaaatcagtgctatctacaagccgaaatttaagcaacaactgtgacacagga
gagaagccagtggttaccttcaaagaaaacattaagacacgagaagtgaacagagaccaa
ggaagaagttttcctcccaaagaggtgagaagggactatagcaaaggaataactgtaact
aagaatgatggaaagaaggacaacaacaagaggaaaactgaaaccaagaaatgcacctta
gaaaagttacaggaaacaggaaagcagaatgtggcagtgcaggtaaaatcccagacagaa
ctaagaaagactccagtgtctgaagccagaaaaacacctgtaactcaaaccccaactcaa
gcaagtaactcccagttcatccccattcatcaccctggagccttccctcctcttcccagc
aggccagggtttccgcccccaacatatgttatccccccgcctgtggcattttctatgggc
tcaggttacaccttcccagctggtgtttctgtcccaggaacctttcttcagcctacagct
cactctccagcaggaaaccaggtgcaagctgggaaacagtcccacattccttacagccag
caacggccctctggaccagggccaatgaaccagggacctcaacaatcacagccaccttcc
cagcaaccccttacatctttaccagctcagccaacagcacagtctacaagccagctgcag
gttcaagctctaactcagcaacaacaatcccctacaaaagctgtgccggctttggggaaa
agcccgcctcaccactctggattccagcagtatcaacaggcagatgcctccaaacagctg
tggaatccccctcaggttcaaggcccattagggaaaattatgcctgtgaaacagccctac
taccttcagacccaagaccccataaaactgtttgagccgtcattgcaacctcctgtaatg
cagcagcagcctctagaaaaaaaaatgaagccttttcccatggagccatataaccataat
ccctcagaagtcaaggtcccagaattctactgggattcttcctacagcatggctgataac
agatctgtaatggcacagcaagcaaacatagaccgcaggggcaaacggtcaccaggagtc
ttccgtccagagcaggatcctgtacccagaatgccgtttgagaaatccttattggagaag
ccctcagagctcatgtcacattcatcctctttcctgtccctcaccggattctctctcaat
caggaaagatacccaaataatagtatgttcaatgaggtatatgggaaaaacctgacatcc
agctccaaagcagaactcagtccctcaatggccccccaggaaacatctctgtattccctt
tttgaagggactccgtggtctccatcacttcctgccagttcagatcattcaacaccagcc
agccagtctcctcattcctctaacccaagcagcctacccagctctcctccaacacacaac
cataattctgttccattctccaattttggacccattgggactccagataacagggataga
aggactgcagatcggtggaaaactgataagccagccatgggtgggtttggcattgattat
ctctcagcaacgtcatcctctgagagcagttggcatcaggccagcactccgagtggcacc
tggacaggccatggcccttccatggaggattcctctgctgtcctcatggaaagcctaaag
tctatctggtccagttccatgatgcatcctggaccttctgctctggagcagctgttaatg
cagcagaagcagaaacagcaacggggacaaggcaccatgaaccctccacactga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (40)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (37)   
DNA sequence (89)   
   RefSeq(nuc) (39)   
   GenBank (25)   
   EMBL (25)   
3D Structure (1)   
   PDB (1)   
Protein domain (5)   
   Pfam (5)   
All databases (156)   

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