KEGG   ORTHOLOGY: K18768
Entry
K18768            Tight     KO                                     
Symbol
blaKPC
Name
beta-lactamase class A KPC [EC:3.5.2.6]
Pathway
map01501  beta-Lactam resistance
Module
M00851  Carbapenem resistance
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    K18768  blaKPC; beta-lactamase class A KPC
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes
    K18768  blaKPC; beta-lactamase class A KPC
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.6  beta-lactamase
     K18768  blaKPC; beta-lactamase class A KPC
Antimicrobial resistance genes [BR:ko01504]
 Gene variants
  beta-Lactamase genes
   Class A [MT]
    K18768  blaKPC; beta-lactamase class A KPC
Antimicrobial resistance: KEGG signatures [br01600.html]
 Signature KOs for antimicrobial resistance
  K18768
Other DBs
COG: COG2367
GO: 0008800
Genes
ECLE: ECNIH2_24690 ECNIH2_25815 ECNIH2_26880
ECLN: ECNIH4_23585
ECLI: ECNIH5_23470
ECLX: LI66_24385
ECLY: LI62_00245
ECLZ: LI64_22410
EHM: AB284_00545
ECLA: ECNIH3_24215
ECLC: ECR091_23505
ECLS: LI67_024640 LI67_024910
KPM: KPHS_p200360
KPH: KPNIH24_26630
KPZ: KPNIH27_26500
KPV: KPNIH29_26585
KPW: KPNIH30_27255
KPY: KPNIH31_22370
KPG: KPNIH32_27890
KPC: KPNIH10_27890
KPQ: KPR0928_26095
KPA: KPNJ1_05677
KPS: KPNJ2_05460
KPNE: KU54_01135
KPNU: LI86_28510
KOK: KONIH1_31710 KONIH1_32230
KOC: AB185_04575
CFD: CFNIH1_25795
CFQ: C2U38_26855
CFAR: CI104_28570
CIR: C2U53_00335 C2U53_02720 C2U53_07760 C2U53_15385
LEI: C2U54_24110
LEH: C3F35_23375
KIN: AB182_00195
EBC: C2U52_00285
SNEV: OI978_28100
PANT: PSNIH1_18700
PANP: PSNIH2_19905
PTHA: OI982_21640
AEA: C2U39_22795 C2U39_23940
AES: C2U30_22455
ACHR: C2U31_12850 C2U31_12860
AG: AAG13410(KPC-1) AAK70220(KPC-2) AAL05630(KPC-3) ABY91240(KPC-5) ACB71165(KPC-6) ACE62798(KPC-7) ACL01102(KPC-4) ACM91559(KPC-9) ACS35345(KPC-10) ADH95186(KPC-11) AGF70638(KPC-15) AGJ01153(KPC-16) AGJ01154(KPC-17) ANY26940(KPC-26)
 » show all
Reference
PMID:11257029
  Authors
Yigit H, Queenan AM, Anderson GJ, Domenech-Sanchez A, Biddle JW, Steward CD, Alberti S, Bush K, Tenover FC
  Title
Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae.
  Journal
Antimicrob Agents Chemother 45:1151-61 (2001)
DOI:10.1128/AAC.45.4.1151-1161.2001
  Sequence
[ag:AAG13410]

  All links  
Ontology (6)   
   KEGG BRITE (4)   
   GO (1)   
   COG (1)   
Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (64)   
   KEGG GENES (63)   
   OC (1)   
Literature (1)   
   PubMed (1)   
All databases (75)   

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