KEGG   Mus musculus (house mouse): 100042314
Entry
100042314         CDS       T01002                                 
Symbol
Gsta5, Gm10639
Name
(RefSeq) glutathione S-transferase alpha 5
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00480  Glutathione metabolism
mmu00980  Metabolism of xenobiotics by cytochrome P450
mmu00982  Drug metabolism - cytochrome P450
mmu00983  Drug metabolism - other enzymes
mmu01100  Metabolic pathways
mmu01524  Platinum drug resistance
mmu05200  Pathways in cancer
mmu05204  Chemical carcinogenesis - DNA adducts
mmu05207  Chemical carcinogenesis - receptor activation
mmu05208  Chemical carcinogenesis - reactive oxygen species
mmu05225  Hepatocellular carcinoma
mmu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    100042314 (Gsta5)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100042314 (Gsta5)
   00982 Drug metabolism - cytochrome P450
    100042314 (Gsta5)
   00983 Drug metabolism - other enzymes
    100042314 (Gsta5)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100042314 (Gsta5)
   05204 Chemical carcinogenesis - DNA adducts
    100042314 (Gsta5)
   05207 Chemical carcinogenesis - receptor activation
    100042314 (Gsta5)
   05208 Chemical carcinogenesis - reactive oxygen species
    100042314 (Gsta5)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100042314 (Gsta5)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    100042314 (Gsta5)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    100042314 (Gsta5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:mmu02000]
    100042314 (Gsta5)
Enzymes [BR:mmu01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     100042314 (Gsta5)
Transporters [BR:mmu02000]
 Other transporters
  Pores ion channels [TC:1]
   100042314 (Gsta5)
SSDB
Motif
Pfam: GST_C GST_C_3 GST_N GST_N_2 GST_N_3
Other DBs
NCBI-GeneID: 100042314
NCBI-ProteinID: NP_001116132
MGI: 3704339
Ensembl: ENSMUSG00000074179
UniProt: E9Q6L7
Position
9:78197210..78212807
AA seq 222 aa
MAGKPVLHHFNARGRMECIRWLLAAAGVEFEEKFIQSPEDLEKLKKDGNLMFDQVPMVEI
DGMKLVQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIGQLLICPPDQKEAK
TALAKDRTKNRYLPAFEKVLKGHGQDYLVGNRLTRVDVHLLELLLYVEEFDASLLTPFPL
LKAFKSRISSLPNVKKFLHPGSQRKPPLDAKQIEEARKIFKF
NT seq 669 nt   +upstreamnt  +downstreamnt
atggccgggaagcccgtgcttcaccacttcaatgcccggggcagaatggagtgcatcagg
tggctcctggctgcagcaggggtggagtttgaagagaagtttatacagagtccggaagat
ttggaaaagctaaaaaaagatgggaatttgatgtttgaccaagtgcccatggtggagatt
gatgggatgaagctggtgcagaccagagccattctcaactacatcgccaccaaatatgac
ctctatgggaaggacatgaaggagagagccctgattgacatgtattcagaaggtatttta
gatctgactgaaatgattgggcaattgttaatatgtcccccagaccaaaaagaagccaag
actgccttggcaaaagacaggaccaaaaaccgttacttgcctgcctttgaaaaggtgttg
aagggccatggacaagactaccttgtgggcaacaggctgaccagggtggacgtccacctg
ctggaacttctcctctatgttgaagagtttgatgccagccttctgactcctttccctctg
ctgaaggccttcaagagcagaatcagcagcctccccaatgtgaagaagttcctacatcct
ggcagccagagaaagcctcccttggatgcaaaacaaattgaagaagcaaggaagattttc
aagttttag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Chemical substance (45)   
   KEGG COMPOUND (45)   
Chemical reaction (23)   
   KEGG ENZYME (1)   
   KEGG REACTION (22)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (5)   
   Pfam (5)   
All databases (101)   

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