KEGG   Mus musculus (house mouse): 100102
Entry
100102            CDS       T01002                                 
Symbol
Pcsk9, FH3, HCHOLA3, Narc1, PC9
Name
(RefSeq) proprotein convertase subtilisin/kexin type 9
  KO
K13050  proprotein convertase subtilisin/kexin type 9 [EC:3.4.21.-]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04979  Cholesterol metabolism
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09154 Digestive system
   04979 Cholesterol metabolism
    100102 (Pcsk9)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:mmu01002]
    100102 (Pcsk9)
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:mmu03110]
    100102 (Pcsk9)
Peptidases and inhibitors [BR:mmu01002]
 Serine peptidases
  Family S8: subtilisin family
   100102 (Pcsk9)
Chaperones and folding catalysts [BR:mmu03110]
 Intramolecular chaperones
  Subtilisin family
   100102 (Pcsk9)
SSDB
Motif
Pfam: PCSK9_C1 PCSK9_C2 Peptidase_S8 PCSK9_C3 Inhibitor_I9
Other DBs
NCBI-GeneID: 100102
NCBI-ProteinID: NP_705793
MGI: 2140260
Ensembl: ENSMUSG00000044254
UniProt: Q80W65
Position
4:complement(106299531..106321522)
AA seq 694 aa
MGTHCSAWLRWPLLPLLPPLLLLLLLLCPTGAGAQDEDGDYEELMLALPSQEDGLADEAA
HVATATFRRCSKEAWRLPGTYIVVLMEETQRLQIEQTAHRLQTRAARRGYVIKVLHIFYD
LFPGFLVKMSSDLLGLALKLPHVEYIEEDSFVFAQSIPWNLERIIPAWHQTEEDRSPDGS
SQVEVYLLDTSIQGAHREIEGRVTITDFNSVPEEDGTRFHRQASKCDSHGTHLAGVVSGR
DAGVAKGTSLHSLRVLNCQGKGTVSGTLIGLEFIRKSQLIQPSGPLVVLLPLAGGYSRIL
NAACRHLARTGVVLVAAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGR
CVDLFAPGKDIIGASSDCSTCFMSQSGTSQAAAHVAGIVARMLSREPTLTLAELRQRLIH
FSTKDVINMAWFPEDQQVLTPNLVATLPPSTHETGGQLLCRTVWSAHSGPTRTATATARC
APEEELLSCSSFSRSGRRRGDWIEAIGGQQVCKALNAFGGEGVYAVARCCLVPRANCSIH
NTPAARAGLETHVHCHQKDHVLTGCSFHWEVEDLSVRRQPALRSRRQPGQCVGHQAASVY
ASCCHAPGLECKIKEHGISGPSEQVTVACEAGWTLTGCNVLPGASLTLGAYSVDNLCVAR
VHDTARADRTSGEATVAAAICCRSRPSAKASWVQ
NT seq 2085 nt   +upstreamnt  +downstreamnt
atgggcacccactgctctgcgtggctgcggtggccgctgttgccgctgttgccgccgctg
ctgctgctgttgctgctactgtgccccaccggcgctggtgcccaggacgaggatggagat
tatgaagagctgatgctcgccctcccgtcccaggaggatggcctggctgatgaggccgca
catgtggccaccgccaccttccgccgttgctccaaggaggcctggaggctgccaggaacc
tacattgtggtgctgatggaggagacccagaggctacagattgaacaaactgcccaccgc
ctgcagacccgggctgcccgccggggctatgtcatcaaggttctacatatcttttatgac
ctcttccctggcttcttggtgaagatgagcagtgacctgttgggcctggccctgaagttg
ccccatgtggagtacattgaggaagactcctttgtcttcgcccagagcatcccatggaac
ctggagcgaattatcccagcatggcaccagacagaggaagaccgctcccctgatggaagc
agccaggtggaggtgtatctcttagataccagcatccagggtgcccatcgggagattgag
ggcagggtcaccatcaccgacttcaacagcgtgccggaggaggatgggacacgcttccac
agacaggcgagcaagtgtgacagccacggcacccacctggcaggtgtggtcagcggccgg
gatgctggtgtggccaagggcaccagcctgcacagcctgcgtgtgctcaactgtcaaggg
aagggcacagtcagcggcaccctcataggcctggagtttattcggaagagtcagctaatc
cagccctcggggccactcgtggttctgctgcccctggccggtgggtatagccgcatcctc
aacgctgcctgccggcacctggcgaggactggggtggtgctggttgcagcagctgggaac
ttccgggacgacgcctgcctctactccccagcttctgctccagaggtcatcacagtcggg
gccacgaatgcccaggaccagccagttaccttggggactttggggactaattttggacgc
tgtgtggatctctttgcccccgggaaggacatcatcggagcgtccagtgactgcagcaca
tgcttcatgtcacagagtgggacctcacaggctgctgcccacgtggccggcattgtggct
cggatgctgagccgggagcccacacttaccctggccgagctgcggcagaggctgatccac
ttctctaccaaagacgtcatcaacatggcctggttccctgaggaccagcaggtgctgacc
cccaacctggtggccacactgccccccagcacccatgagacaggcgggcagctgctctgt
aggacggtgtggtcggcacactcggggcccactcgaacagctacagctacagcccgctgt
gccccagaagaggagctgctgagctgctccagcttctccaggagcgggaggcgtcgtggt
gattggattgaggccataggaggccagcaggtctgcaaggccctcaatgcatttgggggt
gagggtgtctatgccgtcgcgagatgctgcctggttccccgtgccaactgcagcatccac
aacacccctgcagccagagctggcctggagacccatgtccactgccaccagaaggaccat
gttctcacaggctgcagcttccattgggaagtggaagaccttagtgtccggaggcagcct
gcgctgaggtccagacgtcagcctggccagtgcgttggccaccaggcggccagtgtctat
gcttcctgctgccatgccccagggctggaatgcaaaatcaaggagcatgggatctcaggt
ccttcagagcaggtcactgtggcctgcgaagcaggatggaccctgactggatgcaatgtg
ctccctggggcatccctcactctgggagcctacagcgtggacaacctgtgtgtggcaaga
gtccatgacactgccagagcagacaggaccagtggagaagccacagtagctgctgccatc
tgctgccggagccggccttcagcaaaggcctcctgggttcagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (11)   
   RefSeq(nuc) (1)   
   GenBank (5)   
   EMBL (5)   
Protein domain (5)   
   Pfam (5)   
All databases (49)   

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