| Entry |
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| Symbol |
Gck, GLK, Gk, Gls006, HK4, HKIV, HXKP, Hlb62, MODY2
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| Name |
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| KO |
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| Organism |
mmu Mus musculus (house mouse)
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| Pathway |
| mmu00520 | Amino sugar and nucleotide sugar metabolism |
| mmu00524 | Neomycin, kanamycin and gentamicin biosynthesis |
| mmu01250 | Biosynthesis of nucleotide sugars |
| mmu04950 | Maturity onset diabetes of the young |
| mmu05230 | Central carbon metabolism in cancer |
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| Module |
| mmu_M00001 | Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate |
| mmu_M00549 | Nucleotide sugar biosynthesis, glucose => UDP-glucose |
| mmu_M00892 | UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc |
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| Brite |
KEGG Orthology (KO) [BR:mmu00001]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
103988 (Gck)
00052 Galactose metabolism
103988 (Gck)
00500 Starch and sucrose metabolism
103988 (Gck)
00520 Amino sugar and nucleotide sugar metabolism
103988 (Gck)
09110 Biosynthesis of other secondary metabolites
00524 Neomycin, kanamycin and gentamicin biosynthesis
103988 (Gck)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
103988 (Gck)
04910 Insulin signaling pathway
103988 (Gck)
04922 Glucagon signaling pathway
103988 (Gck)
04917 Prolactin signaling pathway
103988 (Gck)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
103988 (Gck)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
103988 (Gck)
04950 Maturity onset diabetes of the young
103988 (Gck)
Enzymes [BR:mmu01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.2 glucokinase
103988 (Gck)
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| SSDB |
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| Motif |
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| Other DBs |
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| Position |
11:complement(5850816..5900081)
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| AA seq |
465 aa
MAVDTTRRGAQSLTLVEQILAEFQLQEEDLKKVMSRMQKEMDRGLKLETHQEASVKMLPT
YVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEAGQWSVKTKHQMYSIPEDAMTGTAE
MLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNN
IVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRQCEVGMIVGTGCNACYMEEMQN
VELVEGDEGRMCVNTEWGAFGNSGELDEFLLEYDRMVDESSVNPGQQLYEKIIGGKYMGE
LVRLVLLKLVEENLLFHGEASEQLRTRGAFETRFVSQVESDSGDRRQILNILSTLGLRPS
VADCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFK
ERFHASVRRLTPNCEITFIESEEGSGRGAALVSAVACKKACMLGQ |
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| NT seq |
1398 nt +upstreamnt +downstreamnt
atggctgtggatactacaaggaggggagcccagtcgttgactctggtagagcagatcctg
gcagagttccagctgcaggaggaagacctgaagaaggtgatgagccggatgcagaaggag
atggaccgtggcctgaagctggagacccatcaggaggccagtgtaaagatgttgcccacc
tacgtgcgttccaccccagaaggctcagaagttggagactttctctccttagacctggga
ggaaccaacttcagggtgatgctggtgaaagtgggggagggggaggcaggacagtggagc
gtgaagacgaaacaccagatgtattccatccccgaggacgccatgacgggcactgcggag
atgctctttgactacatctctgagtgcatctctgacttcctggacaagcatcagatgaaa
cacaagaaactacccctgggcttcaccttctccttccctgtaaggcacgaagacatagac
aagggcatcctgctcaactggaccaagggcttcaaggcctccggagcagaagggaacaac
atcgtgggacttctccgagatgctatcaagaggagaggggactttgagatggatgtggtg
gcaatggtgaatgacacggtggccacaatgatctcctgctactatgaagaccgccaatgt
gaggtcggcatgattgtgggcaccggctgcaacgcctgctacatggaggagatgcagaat
gtggagctggtggaaggcgatgaggggcgcatgtgtgtcaacacagagtggggcgccttc
gggaactccggtgagctggacgagttcctcctggagtacgaccggatggtggatgagagc
tcagtgaaccccggtcagcagctgtacgaaaagatcattggcggaaagtacatgggcgag
ctggtacgacttgtgctgctcaagctggtagaggagaatcttctgttccacggagaggcc
tcagagcagctgcgcacacgtggtgcttttgagacccgttttgtgtcgcaggtggagagc
gactctggggaccgaaggcagatccttaacatcctgagcactctgggccttcgaccctct
gtcgccgactgcgacattgtgcgccgtgcctgtgaaagcgtgtccactcgcgccgcccac
atgtgctcagcaggactagcgggggtcataaatcgcatgcgcgaaagccgcagtgaggac
gtgatgcgcatcacggtgggcgtggatggctccgtgtacaagctgcacccgagcttcaag
gagcggtttcacgccagtgtgcgcaggctgacacccaactgcgaaatcaccttcattgaa
tcagaggagggcagcggcaggggagccgcactggtctctgcggtggcctgcaagaaggct
tgcatgctgggccagtga |
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