KEGG   Mus musculus (house mouse): 107045
Entry
107045            CDS       T01002                                 
Symbol
Lars1, 2310045K21Rik, 3110009L02Rik, Lars, leuRS
Name
(RefSeq) leucyl-tRNA synthetase 1
  KO
K01869  leucyl-tRNA synthetase [EC:6.1.1.4]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00970  Aminoacyl-tRNA biosynthesis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09122 Translation
   00970 Aminoacyl-tRNA biosynthesis
    107045 (Lars1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:mmu01007]
    107045 (Lars1)
  09182 Protein families: genetic information processing
   03016 Transfer RNA biogenesis [BR:mmu03016]
    107045 (Lars1)
   03029 Mitochondrial biogenesis [BR:mmu03029]
    107045 (Lars1)
Enzymes [BR:mmu01000]
 6. Ligases
  6.1  Forming carbon-oxygen bonds
   6.1.1  Ligases forming aminoacyl-tRNA and related compounds
    6.1.1.4  leucine---tRNA ligase
     107045 (Lars1)
Amino acid related enzymes [BR:mmu01007]
 Aminoacyl-tRNA synthetase
  Class I (U)
   107045 (Lars1)
Transfer RNA biogenesis [BR:mmu03016]
 Eukaryotic type
  Aminoacyl-tRNA synthetases (AARSs)
   Multi-aminoacyl-tRNA synthetase complex (MSC)
    107045 (Lars1)
 Prokaryotic type
    107045 (Lars1)
Mitochondrial biogenesis [BR:mmu03029]
 Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial transcription and translation factors
   Other mitochondrial DNA transcription and translation factors
    107045 (Lars1)
SSDB
Motif
Pfam: tRNA-synt_1 Anticodon_1 tRNA-synt_1g tRNA-synt_1e tRNA-synt_1f
Other DBs
NCBI-GeneID: 107045
NCBI-ProteinID: NP_598898
MGI: 1913808
Ensembl: ENSMUSG00000024493
UniProt: Q8BMJ2 Q7TSZ3
Position
18:complement(42335363..42395302)
AA seq 1178 aa
MAGRKGTAKVDFLKEIEKEAQQKWEAEKVFEVSASRLEKQKQSSKGKYFVTFPYPYMNGR
LHLGHTFSLSKCEFAVGYQRLKGKSCLFPFGLHCTGMPIKACADKLKREIELYGCPPDFP
EEEEEEEESSAKPGDIVVRDKAKGKKSKAAAKAGSSKYQWDIMKSLGLSDDDIVKFSEAE
HWLDYFPPLAVQDLKTIGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYT
IYSPKDGQPCMDHDRQTGEGVGPQEYTLVKLKVLEPYPSKLSGLKGKNIFLVAATLRPET
MFGQTNCWVRPDMKYIGFETANGDIFICTQRAARNMSYQGFTKHNGVVPVVKELMGEEIL
GASLSAPLTCYKVVYVLPMLTIKEDKGTGVVTSVPSDSPDDLAALRDLKKKQALRTKFGI
RDDMVLPFEPVPVLEIPGIGNLPAVTVCDELKIQSQNDREKLAEAKEKLYLRGFYDGVML
VDGFKGQKIQHVKKTIQKNMIDAGDALIYMEPEKQVMSRSADECVVALCDQWYLDYGDEN
WKKQTFQCLKNMETFCEESRKNFEASLDWLQEHACSRTYGLGTRLPWDEQWLIESLSDST
IYMAFYTVAHLLQGGDLNGQAESPLGIRPQQMTKDVWDYVFFKDAPFPKTQIPKEKLDQL
KQEFEFWYPVDLRASGKDLIPNHLSYYIYNHVAMWPEQSDKWPVSVRANGHLLLNSEKMS
KSTGNFLTLSQAVDKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEML
ASCSSLRSGPADSFNDRVFASEMNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYREL
ATEGMHRELVFRFIEVQTILLTPFCPHLCEHIWTLLGKPDSIMHASWPVAGPVDESLIRS
SQYLMEVAHDLRLRLKNYMMPAKGKKTDKQPAQRPSHCTIYVAKNYPVWQHITLTTLRSH
FEANNGKLPDNKVIASELGSLPELKKYMKKVMPFVAMIKENMEKKGPRVLDLELEFDEQA
VLMENIVYLTNSLELEHIEVKFASEAEDKVREECCPGKPLNVFRTEPGVPVSLVNPQPSS
GHFSTKIDIRQGDSCESIIRRLMKTDRGIKDLSKVKLMRFDDPLLGPRRVPVLGREHSEK
TLISENAVFHVDLVSKKVHLTENGLRTDIGDTMVYLVH
NT seq 3537 nt   +upstreamnt  +downstreamnt
atggcgggaagaaaaggaactgctaaagtagacttcttgaaggagatcgagaaagaggcc
cagcagaagtgggaagctgagaaagtgtttgaagtcagtgcctcccggctggagaagcag
aagcagagcagcaagggcaaatactttgtcaccttcccatatccatacatgaatggacgc
cttcatttgggacacacgttttccttatccaagtgtgagtttgcagtaggataccagaga
ttaaaaggaaaaagctgtctgtttccctttgggttgcactgtactggtatgcctattaag
gcatgcgctgacaagctgaaaagagaaatagagctgtatggctgccctcctgattttccc
gaggaagaagaggaagaggaagaaagcagtgctaaacctggagatatagtagtgagggat
aaagccaaagggaaaaagagcaaagctgccgccaaagcaggatcttctaagtaccagtgg
gacattatgaaatcccttgggctctctgatgacgacatagtgaagttttctgaagcagag
cactggcttgattatttcccaccactggccgttcaggatctgaagactataggtttgaag
gtagactggcggcgctccttcatcaccacggacgtgaatccttactacgattcctttgtc
aggtggcagtttttaactttaagagaaagaaataaaattaaatttgggaagcggtacact
atttattccccaaaagatggacagccttgcatggatcatgacagacaaactggagagggt
gttggacctcaggaatatactctggtcaaactgaaggtgcttgaaccatatccatcaaaa
ttaagcggcctgaaagggaaaaatatcttcctagtagctgctacactcagacctgagact
atgtttgggcagacaaattgttgggttcggcctgatatgaaatacattgggtttgagaca
gcaaatggagacatcttcatctgtacccagagagcagccaggaatatgtcataccaaggc
ttcaccaagcacaacggagtggtgccggttgtgaaggagttaatgggagaggaaatcctt
ggggcttcactttctgcacccctgacgtgctataaggtggtctacgttctccctatgctg
accattaaagaggataaaggcactggggtggtcacgagcgttccttctgattccccggat
gatcttgcagcactcagagacttgaagaaaaagcaagccttacgaacaaagtttggaatt
agggatgacatggtcctgccgtttgaaccggtgccagtcctggaaatcccagggattgga
aatcttcctgctgtgactgtttgtgatgagctgaaaattcagagccagaatgaccgtgaa
aaacttgcagaagcaaaggagaaattgtatttaagaggattttatgatggtgtaatgcta
gtggatggctttaaaggacagaagatccaacatgtaaagaagactattcagaaaaacatg
attgatgctggagatgcgcttatctacatggagccagaaaaacaagtgatgtcgaggtct
gcagatgagtgcgtcgtggccctgtgtgaccagtggtacttggattatggagatgagaac
tggaagaaacagacatttcagtgcctgaagaacatggaaacattctgcgaggagagcagg
aagaattttgaagcttccttagactggctacaagaacatgcttgctcaagaacgtacggt
ttaggcactcgtctgccttgggatgaacagtggttaatcgaatctctctcggattccaca
atttacatggcgttctacacagtggcacacctgctgcaggggggtgacctgaatgggcag
gcggagtctccactgggcatcagaccccagcagatgacaaaggacgtttgggattatgtg
ttcttcaaggatgctccatttcctaagactcagatcccaaaggagaagctggatcagttg
aagcaggagtttgagttttggtacccagtggaccttcgagcctctggcaaggatctgatt
ccaaatcatctttcatattacatttacaaccatgtggccatgtggccagagcaaagtgac
aagtggcccgtgtctgtccgagcaaatggacacctgctgctcaactcggagaagatgtca
aaatctacgggcaacttcctcactttgagccaagctgttgacaaattttcagctgacgga
atgcgcctggctctggctgatgctggtgacactgttgaagatgctaactttgtggaagcc
atggcagacgcaggcatcctccgtctgtacacatgggtagagtgggtcaaagaaatgctc
gccagctgcagcagcctcagaagtggacctgccgactcattcaatgatcgtgtgtttgcc
agtgaaatgaatgcaggaattataaaaacagatcaaaactatgaaaagatgatgtttaaa
gaagctttgaaaacaggtttttttgagtttcaggctgcgaaagacaaataccgtgaactg
gccacggagggcatgcacagagagcttgtgttccgctttattgaagttcagacaatcctt
ctgactccattctgtccacatttgtgtgagcacatctggacactgcttggaaagcctgat
tcaatcatgcatgcctcatggcctgtggcaggtcccgtggatgagtccttgatccgttcc
tcacagtatctcatggaagtagcacatgaccttagattacggctcaagaattacatgatg
ccagctaaagggaagaagactgacaagcagccagctcagaggccctcacactgcaccatc
tatgtggcaaagaactaccccgtctggcagcacattaccctgacaaccctgcggagccac
tttgaggccaacaatggaaagttgcctgataacaaagtcattgctagtgaactaggcagt
ttgccagagttgaagaaatatatgaagaaagtgatgccattcgttgctatgattaaggaa
aacatggagaagaaagggccgagagtcttggatttagagctggagtttgatgagcaggca
gtgcttatggagaatatagtctacctaaccaattctctcgagctggaacacatagaagtc
aagtttgcctctgaggctgaagataaagtcagggaggagtgctgtcctgggaagccactt
aacgttttcagaacagaacctggtgtgccagtttccctagtaaatcctcagccatcgagt
gggcacttctccaccaaaatcgacatcaggcaaggagatagctgtgagtccataatcaga
cgcttgatgaaaacggaccgagggatcaaagatctttccaaagtgaagctgatgcggttt
gatgatcctctgttggggcctcggcgagttccggtcctggggagagagcacagtgagaag
acactcatttccgagaacgccgttttccacgtggacctggtgagcaagaaagtccacctc
accgagaacgggctgcgcacggacatcggcgacaccatggtctacctggttcactga

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (35)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (28)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (32)   
   RefSeq(nuc) (2)   
   GenBank (15)   
   EMBL (15)   
Protein domain (5)   
   Pfam (5)   
All databases (91)   

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