KEGG   Mus musculus (house mouse): 108037
Entry
108037            CDS       T01002                                 
Symbol
Shmt2, 2700043D08Rik, SHMT
Name
(RefSeq) serine hydroxymethyltransferase 2 (mitochondrial)
  KO
K00600  glycine hydroxymethyltransferase [EC:2.1.2.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00260  Glycine, serine and threonine metabolism
mmu00630  Glyoxylate and dicarboxylate metabolism
mmu00670  One carbon pool by folate
mmu01100  Metabolic pathways
mmu01200  Carbon metabolism
mmu01230  Biosynthesis of amino acids
mmu01240  Biosynthesis of cofactors
mmu01523  Antifolate resistance
Module
mmu_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    108037 (Shmt2)
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    108037 (Shmt2)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    108037 (Shmt2)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    108037 (Shmt2)
Enzymes [BR:mmu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.1  glycine hydroxymethyltransferase
     108037 (Shmt2)
SSDB
Motif
Pfam: SHMT
Other DBs
NCBI-GeneID: 108037
NCBI-ProteinID: NP_082506
MGI: 1277989
Ensembl: ENSMUSG00000025403
UniProt: Q9CZN7
Position
10:complement(127352992..127358313)
AA seq 504 aa
MVSFSLLRTTRPLQRCGQLVCMAARAQHSKVAQTQAGEAAGGWTGQESLSDSDPEMWELL
QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPQTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMREV
CDEVRAHLLADMAHISGLVAAKVIPSPFKYADVVTTTTHKTLRGARSGLIFYRKGVRTVD
PKTGKEIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLRNAQA
MADALLKRGYSLVSGGTDTHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKRKTAKLQDFKSFLLKDPETSQ
RLANLRQQVEQFARGFPMPGFDER
NT seq 1515 nt   +upstreamnt  +downstreamnt
atggtatccttctctttgcttcggaccactcggcctctgcagagatgtggtcagctggtc
tgcatggctgcccgggcccagcacagcaaggtggcccagacgcaggctggggaagcagct
ggaggttggacgggccaggagagtttatcagacagtgaccctgagatgtgggagcttctg
cagagggagaaggacagacagtgtcgcggcctggagctcatcgcctcagagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctcaacaacaagtactcggagggttac
cctggcaagagatactacggaggagcggaagtggtggacgagatcgagctgctctgccag
cgccgggccttggaagcctttgacctggatccggcacagtggggagtcaatgtgcagcca
tactcagggtccccagccaatctggctgcctatacggcccttctgcagcctcatgatcga
atcatggggttggacctgcccgatgggggccatctcacccatggctacatgtctgatgtc
aagcggatctccgccacatccattttcttcgagtctatgccctataagctcaatccccaa
actggcctcatcgactacgaccagctggcgctgaccgctcggcttttccgaccgcggctc
atcatagctggcacgagtgcctatgcccgcctcattgactatgcacgcatgagagaggtc
tgtgatgaggtcagggcacacctgctggcagacatggcccacatcagtggcctggtggct
gccaaggtgatcccctcccctttcaagtacgcggatgttgttaccaccaccactcacaag
acactgcgaggggccaggtcagggctcatcttctaccggaagggagtacgaaccgtagac
cccaagactggcaaagagatcccttatacctttgaggaccgaatcaacttcgctgtgttc
ccatccctacagggtggcccccacaaccacgccattgctgcagtagccgtggctctcaag
caggcctgcacccctatgttccgcgagtactccttacaagtgctgaggaacgcccaggcc
atggctgatgccctgctcaagcgaggatactcgctggtgtctggtggcactgacacccac
ctggtgctggtggacctgcggcccaagggcctggatggagcccgagccgaacgcgtgttg
gaactcgtctccatcacagccaacaagaacacctgtcctggagaccggagcgccattact
ccggggggcttgaggcttggggcccccgcgttgacctctcgccagttccgtgaggacgac
ttccgtagagtcgtcgattttatcgatgagggagtcaacattggcttggaggtgaagcgc
aagactgccaagctccaggatttcaaatccttcctgctcaaagacccagagacaagccag
cgtttggccaacctccggcaacaggtggaacagtttgccaggggcttccccatgcctgga
tttgatgaacgttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (13)   
   KEGG PATHWAY (8)   
   KEGG MODULE (5)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (46)   
   RefSeq(nuc) (2)   
   GenBank (22)   
   EMBL (22)   
Protein domain (1)   
   Pfam (1)   
All databases (88)   

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