KEGG   Mus musculus (house mouse): 110279
Entry
110279            CDS       T01002                                 
Symbol
Bcr, 5133400C09Rik, mKIAA3017
Name
(RefSeq) BCR activator of RhoGEF and GTPase
  KO
K08878  breakpoint cluster region protein [EC:2.7.11.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu05200  Pathways in cancer
mmu05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110279 (Bcr)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    110279 (Bcr)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    110279 (Bcr)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    110279 (Bcr)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     110279 (Bcr)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: Other
  BCR family
   110279 (Bcr)
Membrane trafficking [BR:mmu04131]
 Others
  Rho GTPase associated proteins
   Rho GTPase-activating proteins
    110279 (Bcr)
SSDB
Motif
Pfam: RhoGAP RhoGEF Bcr-Abl_Oligo C2 PH_19 IQ_SEC7_PH PH PH_5
Other DBs
NCBI-GeneID: 110279
NCBI-ProteinID: NP_001074881
MGI: 88141
Ensembl: ENSMUSG00000009681
UniProt: Q6PAJ1 A2RRK7
Position
10:74896384..75020753
AA seq 1270 aa
MVDSVGFAEAWRAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQ
TLLAKEKKSYDRQRWGFRRAAQPPDGAAEPRASAPRPPPAPADGADPAPVEESEARPDGE
GSPSKGRSASARRPAAAASADRDDRGPPTSVAALRSNFEKIRKGPAQPGSADAEKPFYVN
VEFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQQSAGQGLGEAPRPHYRGRSSESS
CGLDGDYEDAELNPRFLKDNLINANGGNRPPWPPLEYQPYQSIYVGGMMVEGEGKSPLLR
SQSTSEQEKRLTWPRRSYSPRSFEDSGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPT
TYRMFRDKSRSPSQNSQQSFDSSSPPTPQCQKRHRQCQVVVSEATIVGVRKTGQIWPSDG
DSTFQGEADSSFGTPPGYGCAADQAEEQRRHQDGLPYIDDSPSSSPHLSSKGRGSLASGA
LDPTKVSELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQ
QIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVA
METAEKCCQANAQFAEISENLRARSNKDVKDSTTKNSLETLLYKPVDRVTRSTLVLHDLL
KHTPSSHPDHSLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVEG
ARKLRHIFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEALPNIPLVPD
EELDALKIKISQIKSDIQREKRANKGSKVMERLRKKLSEQESLLLLMSPSMAFRVHSRNG
KSYTFLISSDYERAEWRESIREQQKKCFKSFSLTSVELQMLTNSCVKLQTVHHIPLTINK
EDDESPGLYGFLHVIVHSATGFKQSSNLYCTLEVDSFGYFVNKAKTRVYRDTTEPNWNEE
FEIELEGSQTLRILCYEKCYNKMKMTKEDGESADKLMGKGQVQLDPQTLQDRDWQRTVID
MNGIEVKLSVKFTSREFSLKRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERR
GMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFT
DEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKETVNKMSLH
NLATVFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQVQVLLYFLQLEAIPAPDSK
RQSILFSTEV
NT seq 3813 nt   +upstreamnt  +downstreamnt
atggtggactcggtgggcttcgccgaggcgtggagggcgcagttcccggactcggagccg
ccgcgcatggagctgcgctcggtgggtgacatcgagcaggagctggagcgctgcaaggcc
tccattaggcgcttggagcaggaggtgaaccaggagcgcttccgcatgatctacctgcag
acgctgctggccaaggagaagaagagctacgatcggcagcgctggggcttccgccgtgca
gcgcagccccccgacggcgccgccgagccccgagcgtccgccccgcgcccgccgcccgcg
cccgccgacggcgcagacccggcgcccgtcgaggagtccgaggcgcggccggacggagag
gggtcaccgagtaaggggcggtcagcgtccgcccgcaggccagcggctgctgcatcggcg
gaccgggacgaccgagggccccccaccagcgtggcggcgctcagatccaacttcgagaag
atccgcaagggacctgcccagcccggctctgccgacgccgagaagcccttctacgtgaac
gtcgagttccaccacgagcgcggcctggtgaaggtcaacgacaaagaggtgtccgaccga
atcagttccctgggcagccaggccatgcaaatggagcgcaagaagtcccagcagagcgcc
gggcagggcctgggggaagcacccagaccccattaccgtgggcgctcctcggaaagcagt
tgcggccttgacggtgactatgaggatgcagagttgaatccccgcttcctgaaggacaac
ctaataaatgccaacggcggcaacaggcccccttggccgcccctggagtaccaaccctac
cagagcatctatgtcggaggcatgatggtggaaggggagggcaagagccctctcctgcga
agccagagcacttcagagcaggagaaacgcctaacctggcctcgcaggtcctactcgcct
cggagtttcgaggacagcggaggtggctacacgccggactgcagctccaacgagaacctc
acctccagcgaggaggacttttcctctggccagtccagccgcgtgtcaccaagccccacc
acctaccgcatgttccgggacaagagccgctcaccctcgcagaattcgcagcagtccttt
gacagcagcagccccccgacgccacagtgccagaagcggcaccggcagtgccaggttgtg
gtgtctgaggctaccatcgtgggtgtccgcaagactgggcagatctggcccagtgatggg
gacagcacctttcaaggggaagcagattcctcgtttggaacaccacctggatatggctgt
gccgcagaccaggctgaggaacagcgccggcaccaggacgggctgccctacatcgatgat
tcaccttcttcctcgccacacctcagcagcaaaggcagaggcagcctggcctcaggcgcc
ctggatcccaccaaagtgagtgagctggatctggaaaagggcctggagatgagaaagtgg
gttttgtccggaatcctggccagcgaggagacgtacctgagccatctggaggccctgctg
ctgcccatgaagcctctgaaagccgctgccaccacctctcagcctgtgctgaccagccag
cagattgagaccattttcttcaaagtgcctgagctctacgagatccacaaggagttctac
gatgggctgttcccccgagtgcagcagtggagccaccagcagcgtgtaggggacctcttc
cagaagctggccagccagctgggtgtgtaccgagcctttgtggataactacggagtggcc
atggaaactgcagagaagtgctgtcaggccaacgctcagtttgcagaaatctctgagaac
ctgcgagccagaagcaacaaggatgtcaaggactcaactaccaagaactctttggaaact
ctgctctacaaacctgtggaccgggtgacgaggagcacgctagtccttcacgacttgcta
aaacacaccccgtccagccatcccgaccattccctgctgcaagacgccctccgaatctct
cagaacttcctgtccagcatcaacgaggagatcacgccccgccgacagtccatgacggtg
aaaaaaggagagcaccggcagctgctgaaggacagctttatggtagagctggtggagggg
gcccgcaagctgcgtcacatcttcctgttcactgacctgctcctctgcaccaagctgaag
aagcaaagtggaggcaaaacccagcaatatgactgtaaatggtacattccgctcacggac
ctcagcttccagatggtggatgaattggaggcactacccaacatccctctggtgccagat
gaggaactggatgccttgaagatcaaaatctcccaaatcaagagcgacatccaacgagag
aagagagcaaataagggcagcaaggtcatggagaggctgaggaagaagctgtcagagcag
gagtcactgctgctgttaatgtctcccagcatggccttccgcgttcacagtcgcaacggc
aagagttacacgttccttatttcctctgactatgagcgagccgagtggagagaaagcatc
cgagagcagcagaagaaatgtttcaaaagtttctctctgacatctgtggagctacaaatg
ctgaccaactcatgtgtaaaacttcagacggttcaccacattccactgaccatcaacaaa
gaagatgacgagtctcctggactctacggcttcctgcatgtcatcgtccactcagccacc
ggctttaagcagagctcaaatctctactgcaccctggaggtggattcctttggatatttt
gtgaataaagcaaagactcgagtctacagggacacaactgagccaaactggaatgaggag
tttgagatagagctagaaggctcccagaccctgcggatactatgttatgaaaagtgttac
aacaaaatgaagatgacgaaggaagatggtgagagcgcagacaagctcatggggaaaggc
caggtccagctggacccccaaaccctacaggacagagactggcagcggactgtcatcgac
atgaatggaattgaagtgaaactctccgtcaagttcacgagcagggagttcagcctgaag
agaatgccctcccgcaaacagacaggggtcttcggtgtcaagattgctgtagtcacaaag
agagagaggtccaaggtaccttacattgtgcgccagtgtgtggaagagatcgagcgccgg
ggtatggaggaggtgggcatctaccgagtgtctggagtggccacagacatccaggcactg
aaggcagcctttgatgtcaataacaaggatgtgtccgtgatgatgagcgagatggacgtg
aacgccattgccggcacgctgaagctctacttccgtgagctgcccgagcccctcttcacg
gatgagttctaccctaacttcgcagaaggcattgctctttcagaccccgtcgcaaaggag
agctgcatgctgaacctgctgctgtccctcccagaagccaacctgctcaccttcctcttc
ctcctggaccacctgaaaagggtagctgaaaaggagacggtgaacaagatgtccctgcac
aacctcgccacggtctttggccccacactgcttcggccctcagagaaggaaagcaagctc
cctgctaaccccagccagcccatcaccatgactgacagctggtccctggaggtcatgtcc
caggtccaagtgttgctgtacttcctgcagctggaggccatccctgcccctgacagcaag
agacagagcatcctgttttccactgaagtctaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (17)   
   RefSeq(nuc) (3)   
   GenBank (7)   
   EMBL (7)   
Protein domain (8)   
   Pfam (8)   
All databases (62)   

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