KEGG   Mus musculus (house mouse): 11441
Entry
11441             CDS       T01002                                 
Symbol
Chrna7, Acra7, alpha7, nAchR
Name
(RefSeq) cholinergic receptor, nicotinic, alpha polypeptide 7
  KO
K04809  nicotinic acetylcholine receptor alpha-7
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04020  Calcium signaling pathway
mmu04080  Neuroactive ligand-receptor interaction
mmu04725  Cholinergic synapse
mmu05010  Alzheimer disease
mmu05022  Pathways of neurodegeneration - multiple diseases
mmu05033  Nicotine addiction
mmu05207  Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    11441 (Chrna7)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    11441 (Chrna7)
 09150 Organismal Systems
  09156 Nervous system
   04725 Cholinergic synapse
    11441 (Chrna7)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    11441 (Chrna7)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    11441 (Chrna7)
   05022 Pathways of neurodegeneration - multiple diseases
    11441 (Chrna7)
  09165 Substance dependence
   05033 Nicotine addiction
    11441 (Chrna7)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:mmu04040]
    11441 (Chrna7)
Ion channels [BR:mmu04040]
 Ligand-gated channels
  Acetylcholine (nicotinic)
   11441 (Chrna7)
SSDB
Motif
Pfam: Neur_chan_LBD Neur_chan_memb SUR7
Other DBs
NCBI-GeneID: 11441
NCBI-ProteinID: NP_031416
MGI: 99779
Ensembl: ENSMUSG00000030525
UniProt: P49582 Q53YJ9 Q8CC01
Position
7:complement(62748440..62862274)
AA seq 502 aa
MCGRRGGIWLALAAALLHVSLQGEFQRRLYKELVKNYNPLERPVANDSQPLTVYFSLSLL
QIMDVDEKNQVLTTNIWLQMSWTDHYLQWNMSEYPGVKNVRFPDGQIWKPDILLYNSADE
RFDATFHTNVLVNASGHCQYLPPGIFKSSCYIDVRWFPFDVQQCKLKFGSWSYGGWSLDL
QMQEADISSYIPNGEWDLMGIPGKRNEKFYECCKEPYPDVTYTVTMRRRTLYYGLNLLIP
CVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFAST
MIIVGLSVVVTVIVLRYHHHDPDGGKMPKWTRIILLNWCAWFLRMKRPGEDKVRPACQHK
PRRCSLASVELSAGAGPPTSNGNLLYIGFRGLEGMHCAPTPDSGVVCGRLACSPTHDEHL
MHGTHPSDGDPDLAKILEEVRYIANRFRCQDESEVICSEWKFAACVVDRLCLMAFSVFTI
ICTIGILMSAPNFVEAVSKDFA
NT seq 1509 nt   +upstreamnt  +downstreamnt
atgtgcggccggcggggaggcatctggctggctctggccgcggcgctgctgcacgtgtcc
ctgcaaggcgagttccagaggaggctgtacaaggagctggtcaagaactacaacccgctg
gagaggccggtggccaacgactcgcagccgctcaccgtgtacttctccctgagcctcctg
cagatcatggatgtggatgagaagaaccaagttttaaccaccaacatttggctacaaatg
tcttggacagatcactatttgcagtggaacatgtctgagtaccccggagtgaaaaatgtt
cgttttccagatggccagatttggaaaccagacattctcctctataacagtgcagatgaa
cgctttgatgccacattccacaccaacgtcttggtgaatgcatctgggcattgccagtat
ctccctccaggcatattcaagagctcctgctacatcgatgtacgctggttcccttttgat
gtgcagcagtgcaaactgaagtttgggtcctggtcctatggagggtggtccttggacctg
cagatgcaagaggcagatatcagcagctatatccccaatggagaatgggatctcatggga
atccctggcaaaaggaatgagaagttctatgaatgctgcaaagagccatacccagatgtc
acctacacagtaaccatgcgccgtaggacactctactatggcctcaacctgctcattcct
tgtgtgctcatttcagccctggctttgctggtattcttgctgcctgcagactctggagag
aaaatctctcttggaataactgtcttactttctctgactgtcttcatgctgcttgtggct
gagatcatgccagcaacatctgattccgtgcccttgatagcacagtacttcgccagcacc
atgatcatcgtgggcctctcagtggtcgtgacagtgattgtgctgcgatatcaccaccat
gaccctgatggtggcaaaatgcctaagtggaccaggatcattcttctgaattggtgtgca
tggtttctgcgcatgaagaggccgggagaggacaaggtgcggccggcttgtcagcacaag
cctcggcgctgcagcctggccagtgtggagctgagcgcaggtgcggggccacccaccagc
aatggcaacctgctctacattggcttccgaggcctggagggcatgcactgtgccccaact
ccagactctggggtcgtgtgtggtcgtttggcctgctccccaacacatgatgagcacctc
atgcatggtacacacccctctgatggggaccccgacctggccaagatcctggaggaggtc
cgctacatcgccaaccgcttccgctgccaggatgagagtgaggtgatctgcagtgagtgg
aagtttgcggcctgtgtggtggaccgcttgtgcctcatggccttttcggtttttaccatc
atctgcaccatcggcatcctcatgtcagccccaaactttgtggaggctgtgtccaaagac
tttgcttaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (19)   
   RefSeq(nuc) (1)   
   GenBank (9)   
   EMBL (9)   
Protein domain (3)   
   Pfam (3)   
All databases (56)   

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