KEGG   Mus musculus (house mouse): 11487
Entry
11487             CDS       T01002                                 
Symbol
Adam10, 1700031C13Rik, MADM, kuz, kuzbanian
Name
(RefSeq) a disintegrin and metallopeptidase domain 10
  KO
K06704  disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04148  Efferocytosis
mmu05010  Alzheimer disease
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    11487 (Adam10)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    11487 (Adam10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:mmu01002]
    11487 (Adam10)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:mmu04090]
    11487 (Adam10)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.81  ADAM10 endopeptidase
     11487 (Adam10)
Peptidases and inhibitors [BR:mmu01002]
 Metallo peptidases
  Family M12: astacin/adamalysin family
   11487 (Adam10)
CD molecules [BR:mmu04090]
 Proteins
  11487 (Adam10)
SSDB
Motif
Pfam: Reprolysin_2 Reprolysin_5 Reprolysin_3 ADAM10_Cys-rich Reprolysin_4 Disintegrin Reprolysin Pep_M12B_propep Peptidase_M66
Other DBs
NCBI-GeneID: 11487
NCBI-ProteinID: NP_031425
MGI: 109548
Ensembl: ENSMUSG00000054693
UniProt: O35598 Q6NZC0
Position
9:70586133..70687511
AA seq 749 aa
MVLPTVLILLLSWAAGLGGQYGNPLNKYIRHYEGLSYNVDSLHQKHQRAKRAVSHEDQFL
LLDFHAHGRQFNLRMKRDTSLFSDEFKVETSNKVLDYDTSHIYTGHIYGEEGSFSHGSVI
DGRFEGFIKTRGGTFYIEPAERYIKDRILPFHSVIYHEDDINYPHKYGPQGGCADHSVFE
RMRKYQMTGVEEGARAHPEKHAASSGPELLRKKRTTLAERNTCQLYIQTDHLFFKYYGTR
EAVIAQISSHVKAIDTIYQTTDFSGIRNISFMVKRIRINTTSDEKDPTNPFRFPNIGVEK
FLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLN
TGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPGESKNLGQKENGNYIMYA
RATSGDKLNNNKFSLCSIRNISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQC
KDDCCFDANQPEGKKCKLKPGKQCSPSQGPCCTAQCAFKSKSEKCRDDSDCAKEGICNGF
TALCPASDPKPNFTDCNRHTQVCINGQCAGSICEKYDLEECTCASSDGKDDKELCHVCCM
KKMAPSTCASTGSLQWSKQFSGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLARLKK
AIFSPQLYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSNPKLPPPKPLPGT
LKRRRPPQPIQQPPRQRPRESYQMGHMRR
NT seq 2250 nt   +upstreamnt  +downstreamnt
atggtgttgccgacagtgttaattctgctcctctcctgggcggcggggctgggaggtcag
tatggaaatcctttaaataaatatattagacattatgaaggattatcttacaatgtggat
tcattacaccaaaaacaccagcgtgccaaacgagcagtctcacatgaggaccagttttta
cttctagatttccatgctcatggaagacagttcaacctacgaatgaagagggacacttcc
ctttttagtgatgaatttaaagtagaaacatcaaataaagtacttgattatgatacctct
catatttacactggacatatttatggtgaagaaggaagctttagtcatgggtctgtcatt
gatggaagatttgaaggtttcatcaagactcgtggtggcacgttttacattgagccagca
gagagatacattaaagatcgaatcctgccatttcactctgtcatttatcatgaagatgat
attaactatccccataaatacggcccacaggggggctgtgcagatcactccgtttttgaa
aggatgaggaagtaccaaatgactggagtagaggaaggagcccgggcacatccagagaag
catgctgctagtagtggtcctgagctcctgaggaaaaaacgcacaactctggctgaaaga
aatacttgtcagctctatatccagacagatcacctgttctttaaatactatggaacacga
gaagctgtgattgctcagatatccagtcatgttaaagcaattgatacaatttaccagact
acagacttctccggaatccgtaacatcagcttcatggtgaaacgcataagaatcaataca
acctctgatgaaaaagaccctacaaatcctttccgtttcccaaatattggtgtggagaag
ttcctggagttgaattctgagcagaatcatgatgactactgcctggcctatgtcttcaca
gaccgggattttgatgatggtgttcttggtctggcctgggttggagcaccttcaggaagc
tctgggggaatatgtgagaaaagcaagttgtattcagatggcaagaagaagtcattgaac
acaggcatcattactgttcagaactatggctcccatgtgcctcccaaagtctctcatatt
acgtttgctcatgaagttggacataactttggatctccacatgattctggaacagagtgt
actccaggagagtctaagaacttaggacaaaaagaaaatggcaattacatcatgtatgca
agagcaacatctggggacaaacttaacaacaacaaattttcactctgcagcattagaaac
ataagccaagtgcttgagaagaagaggaacaactgttttgttgaatctggccagcctatc
tgtggaaacgggatggtggaacaaggggaagagtgtgactgtggctacagtgaccagtgc
aaagatgattgctgcttcgatgccaaccagccagaggggaagaaatgcaagctgaagcct
gggaagcagtgcagtccgagtcaaggaccctgctgtacagcacagtgtgcattcaagtca
aagtctgaaaagtgccgggatgattctgactgtgcaaaggaagggatatgcaatggcttc
acagccctttgcccagcatctgatcccaagcccaactttacagactgtaacaggcacaca
caagtgtgcattaatgggcaatgtgcaggttctatttgtgaaaagtatgacttggaggag
tgcacctgtgccagctctgatggcaaagatgataaggaattatgccatgtttgctgcatg
aagaaaatggctccatcaacttgtgccagtacaggctctttgcagtggagcaagcagttc
agtggtcggactatcactctgcagccgggctctccatgtaatgacttcagaggctactgt
gatgttttcatgcggtgcagattagtagatgctgatggccctctagctaggctgaaaaaa
gccatttttagtccacaactctatgaaaacattgctgagtggattgtggctcactggtgg
gcagtactgcttatgggaattgccctgatcatgttaatggctggatttatcaagatttgc
agtgttcacactccaagtagtaatccaaagttgccgcctcctaaaccacttccaggcact
ttaaagaggaggagaccgccacagcccattcagcagcccccgcgtcagaggccccgagag
agttatcaaatgggacacatgcgacgctaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (28)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (20)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (26)   
   RefSeq(nuc) (2)   
   GenBank (12)   
   EMBL (12)   
Protein domain (9)   
   Pfam (9)   
All databases (76)   

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