KEGG   Mus musculus (house mouse): 11938
Entry
11938             CDS       T01002                                 
Symbol
Atp2a2, 9530097L16Rik, D5Wsu150e, SERCA2, SERCA2B, Serca2a, mKIAA4195
Name
(RefSeq) ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
  KO
K05853  P-type Ca2+ transporter type 2A [EC:7.2.2.10]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04020  Calcium signaling pathway
mmu04022  cGMP-PKG signaling pathway
mmu04024  cAMP signaling pathway
mmu04148  Efferocytosis
mmu04260  Cardiac muscle contraction
mmu04261  Adrenergic signaling in cardiomyocytes
mmu04380  Osteoclast differentiation
mmu04919  Thyroid hormone signaling pathway
mmu04972  Pancreatic secretion
mmu05010  Alzheimer disease
mmu05017  Spinocerebellar ataxia
mmu05022  Pathways of neurodegeneration - multiple diseases
mmu05410  Hypertrophic cardiomyopathy
mmu05412  Arrhythmogenic right ventricular cardiomyopathy
mmu05414  Dilated cardiomyopathy
mmu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    11938 (Atp2a2)
   04024 cAMP signaling pathway
    11938 (Atp2a2)
   04022 cGMP-PKG signaling pathway
    11938 (Atp2a2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    11938 (Atp2a2)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    11938 (Atp2a2)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    11938 (Atp2a2)
   04261 Adrenergic signaling in cardiomyocytes
    11938 (Atp2a2)
  09154 Digestive system
   04972 Pancreatic secretion
    11938 (Atp2a2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    11938 (Atp2a2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    11938 (Atp2a2)
   05017 Spinocerebellar ataxia
    11938 (Atp2a2)
   05022 Pathways of neurodegeneration - multiple diseases
    11938 (Atp2a2)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    11938 (Atp2a2)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    11938 (Atp2a2)
   05414 Dilated cardiomyopathy
    11938 (Atp2a2)
   05415 Diabetic cardiomyopathy
    11938 (Atp2a2)
Enzymes [BR:mmu01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.10  P-type Ca2+ transporter
     11938 (Atp2a2)
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Cation_ATPase_N Hydrolase Hydrolase_3 HAD
Other DBs
NCBI-GeneID: 11938
NCBI-ProteinID: NP_001103610
MGI: 88110
Ensembl: ENSMUSG00000029467
UniProt: O55143 Q5DTI2
Position
5:complement(122591576..122640288)
AA seq 1044 aa
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDKVEGDTCSLNEFSITGSTYAPIGEVQKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGV
KQKIMSVIREWGSGSDTLRCLALATHDNPLKREEMHLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL
SPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFDGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEQPGKECVQPATKSSCSLSACTDGISWPF
VLLIMPLVVWVYSTDTNFSDMFWS
NT seq 3135 nt   +upstreamnt  +downstreamnt
atggagaacgctcacacaaagaccgtggaggaggtgctgggccacttcggggtcaacgag
agcacggggctgagcttggagcaggtcaagaagctcaaggagagatggggctccaacgaa
ttgccggctgaagaaggaaaaaccttgctggaacttgtgattgagcagtttgaagactta
ctagttagaattttactgctggcagcatgtatatctttcgttttggcttggttcgaggaa
ggggaagaaacgattacagcctttgtagagccgtttgtaattctgcttatcttggtagcc
aatgcaatcgtgggtgtgtggcaggaaagaaatgctgaaaatgcaatagaagctcttaag
gaatatgagcctgaaatgggcaaagtgtatcgacaggacagaaagagtgtgcaacgaatt
aaagctaaagacatagttcctggtgatatagtggaaattgctgttggtgacaaagttcct
gctgatattagattgacatccatcaagtctacaactctaagagtcgaccagtcaattctt
acaggtgaatctgtctccgtcatcaagcatactgaccctgtccctgacccccgagctgtt
aatcaagacaaaaagaacatgctcttttctggtacaaacattgctgctgggaaagctatg
ggagtggtggtggcaactggagttaatactgagatcggcaagatccgggatgaaatggtg
gcaacagaacaggagagaacacccctacagcagaagctagacgagtttggggagcagctt
tccaaagttatctccctcatttgcattgcagtctggatcatcaacattgggcatttcaat
gacccagttcatggtggctcctggatcaggggtgccatctactactttaagattgccgtg
gccctggctgttgccgcaatccctgagggtctgcctgctgtcatcaccacctgcttagct
cttggaactcgtaggatggcaaagaaaaatgctatcgttcgaagtctgccttctgtggag
acccttggttgtacttctgttatctgctcagataagacaggcacacttaccacaaaccag
atgtccgtgtgcaggatgttcattctggacaaagtagaaggtgacacttgttcccttaat
gagttcagcataactggatccacatatgcaccaattggagaagtgcaaaaggatgataag
ccagtgaagtgccatcagtatgacgggcttgtagagttagccaccatctgtgctctgtgt
aatgactctgctttggattataatgaggcaaagggtgtgtatgagaaagttggagaagct
accgagactgctctcacgtgcctggtggagaagatgaatgtatttgatactgagctgaag
gggctttctaaaatagagcgtgcaaacgcctgcaactcggtcataaagcagctgatgaag
aaggagttcactctggagttttcacgggatagaaaatcaatgtccgtctattgtacccca
aacaagccaagccggacatccatgagcaagatgtttgtgaagggggctccagaaggtgtc
atcgataggtgcacccacatccgagttggaagtaccaaggtccccatgactcctggtgtc
aaacagaagattatgtctgtcattcgggagtggggcagtggcagcgacacgctacggtgc
ctggctctggccactcatgacaacccactgaagagagaggagatgcacctggaagactct
gctaacttcatcaaatacgagaccaacctgactttcgtcggctgtgtgggcatgctggat
cctcccaggattgaagtagcctcttctgtgaagctgtgccggcaagcaggcatccgggtc
atcatgatcactggagacaacaaaggcaccgctgtggccatctgtcgccgcattggcatc
tttgggcaggatgaggatgtgacatcaaaggcttttacagggcgagagtttgatgaatta
agcccttcagcccagagagatgcctgcttaaatgcccgctgttttgctcgagttgaacct
tcccacaagtctaagattgttgagttccttcagtcctttgatgagatcacagctatgact
ggtgatggtgtgaatgatgctcctgctctgaagaaatctgaaatcgggattgccatgggc
tcagggactgcagtggctaagactgcttctgagatggtcctggcagatgacaacttctcc
accattgtggctgctgttgaggaggggcgagccatctacaacaacatgaagcagttcatc
cgctacctcatctcatccaacgtgggggaagtggtctgtatcttcctgacggcagccctt
gggtttcctgaggctttaattcctgtccagttactctgggtcaatctggtgacagatggt
ctgcctgccactgcgctggggttcaatcctccagacctggacatcatgaacaaacccccc
cggaacccaaaagaaccactgatcagcgggtggctctttttccgttacctggctattggc
tgttatgttggcgctgccaccgtgggtgctgctgcatggtggttcatcgctgctgacggc
ggtccaagagtctccttctaccagctgagtcatttcctacagtgtaaggaggacaaccca
gacttcgatggagtggattgtgcaatctttgagtccccatatccaatgacaatggcactt
tctgttctagtaaccatagagatgtgtaatgccctcaacagcttgtctgaaaaccagtct
ttgctgaggatgcccccctgggagaatatctggctcgtgggctccatctgcttgtccatg
tcacttcacttcttgatcctctacgtggaacctttgccgctcattttccagatcacaccg
ctgaatctgacccagtggctgatggtgctgaaaatctccttgcctgtgatcctcatggat
gagacgctcaagtttgtggcccgaaactacctggaacaacccggtaaagagtgtgtgcag
cctgccaccaaatcttcctgctccctgtcggcatgcaccgatggcatttcctggccgttt
gtgctgctcattatgcccctggtggtctgggtctacagcacagacactaactttagcgat
atgttctggtcttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (16)   
   KEGG PATHWAY (16)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (28)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (67)   
   RefSeq(nuc) (3)   
   GenBank (32)   
   EMBL (32)   
Protein domain (7)   
   Pfam (7)   
All databases (127)   

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