KEGG   Mus musculus (house mouse): 12005
Entry
12005             CDS       T01002                                 
Symbol
Axin1, Axin, Fu, Kb, Ki, fused, kinky, knobbly
Name
(RefSeq) axin 1
  KO
K02157  axin 1
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04310  Wnt signaling pathway
mmu04390  Hippo signaling pathway
mmu04550  Signaling pathways regulating pluripotency of stem cells
mmu04934  Cushing syndrome
mmu05010  Alzheimer disease
mmu05022  Pathways of neurodegeneration - multiple diseases
mmu05165  Human papillomavirus infection
mmu05200  Pathways in cancer
mmu05210  Colorectal cancer
mmu05213  Endometrial cancer
mmu05217  Basal cell carcinoma
mmu05224  Breast cancer
mmu05225  Hepatocellular carcinoma
mmu05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    12005 (Axin1)
   04390 Hippo signaling pathway
    12005 (Axin1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    12005 (Axin1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    12005 (Axin1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    12005 (Axin1)
   05225 Hepatocellular carcinoma
    12005 (Axin1)
   05226 Gastric cancer
    12005 (Axin1)
   05217 Basal cell carcinoma
    12005 (Axin1)
   05213 Endometrial cancer
    12005 (Axin1)
   05224 Breast cancer
    12005 (Axin1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    12005 (Axin1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    12005 (Axin1)
   05022 Pathways of neurodegeneration - multiple diseases
    12005 (Axin1)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    12005 (Axin1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mmu01009]
    12005 (Axin1)
Protein phosphatases and associated proteins [BR:mmu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     12005 (Axin1)
SSDB
Motif
Pfam: DIX RGS AXIN1_TNKS_BD Axin_b-cat_bind
Other DBs
NCBI-GeneID: 12005
NCBI-ProteinID: NP_033863
MGI: 1096327
Ensembl: ENSMUSG00000024182
UniProt: O35625 E9QMJ8
Structure
Position
17:26350294..26414784
AA seq 863 aa
MNVQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDSRPVNHSFCSGKGTSIKSETSTAT
PRRSDLDLGYEPEGSASPTPPYLRWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA
CSGFRKLEPCDSNEEKRLKLARAIYRKYILDSNGIVSRQTKPATKSFIKDCVMKQQIDPA
MFDQAQTEIQSTMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGMSGYLPT
LNEDEEWKCDQDADEDDGRDPLPPSRLTQKLLLETAAPRAPSSRRYNEGRELRYGSWREP
VNPYYVNSGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESI
QVNGRVPLPHIPRTYRMPKEIRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE
EGEDGEMPSGPMASHKLPSVPAWHHFPPRYVDMGCSGLRDAHEENPESILDEHVQRVMRT
PGCQSPGPGHRSPDSGHVAKTAVLGGTASGHGKHVPKLGLKLDTAGLHHHRHVHHHVHHN
SARPKEQMEAEVARRVQSSFSWGPETHGHAKPRSYSENAGTTLSAGDLAFGGKTSAPSKR
NTKKAESGKNANAEVPSTTEDAEKNQKIMQWIIEGEKEISRHRKAGHGSSGLRKQQAHES
SRPLSIERPGAVHPWVSAQLRNSVQPSHLFIQDPTMPPNPAPNPLTQLEEARRRLEEEEK
RANKLPSKQRYVQAVMQRGRTCVRPACAPVLSVVPAVSDLELSETETKSQRKAGGGSAPP
CDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEE
VREDEAVLPVFEEKIIGKVEKVD
NT seq 2592 nt   +upstreamnt  +downstreamnt
atgaatgtccaggagcagggtttccccttggacctcggagcaagtttcaccgaagatgcc
ccccggcccccagtgcctggagaagagggagaactggtatctactgattcgaggcctgtc
aaccacagtttctgttctgggaaaggtaccagcattaaaagtgagacctcaacagccacc
ccaagacgttcagatctggatctgggatatgagcccgagggcagtgcctcccccacccca
ccatatttgaggtgggctgagtcactgcattccttactggatgaccaagatgggatcagc
ctgttcaggactttcctgaagcaggagggctgtgctgacctgctggacttctggtttgcc
tgcagtggcttcaggaagcttgagccctgtgactcaaatgaggaaaagaggctgaagctg
gcaagagccatctaccgaaagtacatcctggatagcaatggcattgtgtccagacaaacc
aagccagccactaagagcttcataaaggactgtgtcatgaagcagcagatagatcctgcc
atgtttgaccaggcacagacagaaatccagtccaccatggaggagaatacctacccttcc
tttcttaagtctgacatttatttggagtacacaaggacaggctcagagagtccgaaggtc
tgcagtgaccagagctcagggtctggaacagggaagggcatgtctggatacctgcccact
ttgaatgaggatgaagaatggaaatgtgaccaagatgcagatgaggatgatggccgagac
cctctcccccccagcaggctcacccagaagctgctattggagactgctgccccgagggcc
ccctcaagtagacggtacaacgaaggcagagagctcaggtatggatcttggagggagccc
gtcaacccctactacgtcaactctggctatgccctggccccagccaccagtgccaatgac
agtgagcagcagagcctgtccagtgatgctgacacgctatcccttacggacagtagtgtg
gatggaatccccccatacaggatccgtaagcagcaccgaagggagatgcaggagagtatc
caagtcaatgggcgggtacctctacctcacattcctcgcacttaccgaatgccaaaggag
atccgggtagagccacagaaatttgctgaagagcttattcaccgtctagaggctgtccag
cgcactcgagaggctgaagaaaagttggaggaacggctgaagcgtgtacgcatggaggaa
gaaggggaggatggtgaaatgccttctggccccatggcaagtcacaagctgccttctgtc
ccagcttggcaccatttcccaccccgctatgtggatatgggctgctctggactgcgggat
gcccatgaggagaatcctgagagcatcctggatgagcacgtgcaaagggtcatgaggaca
cctggctgccagtcacctggcccaggccaccgctctcctgacagtgggcatgtggctaag
actgcagtgctagggggtacagcctccgggcatgggaagcatgttcctaagttagggttg
aagctggatacagctggcctgcaccatcatagacatgtccaccaccatgttcaccataat
tcagctagacctaaggagcaaatggaggctgaagttgcccgcagggtccagagcagcttc
tcgtggggcccagaaacacatggtcatgccaagccccggagctattccgagaacgcaggc
accaccctcagtgctggggatttggcctttggtggtaaaactagtgcaccttccaaaaga
aacaccaagaaggctgaatctgggaagaatgccaatgctgaggtacccagtaccacagag
gacgctgagaagaaccagaagatcatgcagtggatcattgagggagagaaggagatcagt
agacaccggaaggcaggccatgggtcttctgggttgaggaagcagcaggcccatgaaagc
tccaggcccttgtccatcgagcgtcctggggccgtgcacccctgggtcagcgctcagctt
cggaattctgtccagccttctcatcttttcatccaagatcccacaatgccacccaatcca
gcccctaatcccctgacccagctggaagaggcccgcaggcgtttggaagaagaagaaaag
agagcaaacaaactgccctccaagcagaggtatgtgcaggcagtcatgcagcggggacgc
acctgtgtcaggccagcttgtgcaccggtgctgagtgtggtaccagccgtgtcggacttg
gaactctccgagacagagacaaaatcacaaagaaaggcaggtggcgggagtgcaccacca
tgtgacagcattgttgtggcctactatttctgtggggaacccatcccctaccggaccctg
gtgaggggccgtgctgtcaccctgggccagttcaaggagctgctaaccaagaaggggagc
tacagatactactttaagaaagtgagtgatgagtttgactgtggtgtggtatttgaggaa
gtacgggaggatgaggccgtcttgcctgtctttgaagaaaagatcatcggcaaggtggaa
aaggtggactga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (14)   
   KEGG PATHWAY (14)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (24)   
   RefSeq(nuc) (6)   
   GenBank (9)   
   EMBL (9)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   Pfam (4)   
All databases (72)   

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