KEGG   Mus musculus (house mouse): 12039
Entry
12039             CDS       T01002                                 
Symbol
Bckdha, BCKAD, BCKDE1A, E1[a]
Name
(RefSeq) branched chain ketoacid dehydrogenase E1, alpha polypeptide
  KO
K00166  2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00280  Valine, leucine and isoleucine degradation
mmu00640  Propanoate metabolism
mmu00785  Lipoic acid metabolism
mmu01100  Metabolic pathways
mmu01210  2-Oxocarboxylic acid metabolism
Module
mmu_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    12039 (Bckdha)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    12039 (Bckdha)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    12039 (Bckdha)
Enzymes [BR:mmu01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.4  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
     12039 (Bckdha)
SSDB
Motif
Pfam: E1_dh TPP_enzyme_C DXP_synthase_N MASE1
Other DBs
NCBI-GeneID: 12039
NCBI-ProteinID: NP_001390439
MGI: 107701
Ensembl: ENSMUSG00000060376
Position
7:complement(25329371..25358178)
AA seq 463 aa
MAIVMSAAKIWRPSRGLRQAALLLLGRSGVRGLARSVAFSAGERAMDLAGARQHPSRQQQ
QQFPSLDDKPQFPGASAEFVDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEEV
LKFYRSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALERTDLVFGQYREAG
VLMYRDYPLELFMSQCYGNVNDPGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYA
AKRANANRIVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGD
GIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDS
SAYRSVDEVNYWDKQDHPISRLRQYLLNQGWWDEEQEKAWRKQSRKKVMEAFEQAERKLK
PNPSLLFSDVYQEMPAQLRRQQESLARHLQTYGEHYPLDHFDK
NT seq 1392 nt   +upstreamnt  +downstreamnt
atggcgatagtgatgtctgcggccaagatctggaggccgagccgtggcctgcgccaggct
gctcttctcctgttgggacgatctggggttcggggcttggctagatctgttgccttcagt
gctggggagagagccatggacctcgcgggtgctaggcagcaccccagcaggcagcagcaa
cagcagttcccatccctggacgacaagccccagttcccaggggcctctgcagagtttgta
gacaagcttgagttcatccagcccaatgtcatctccggcatccccatctaccgtgtcatg
gaccgccagggccagatcatcaaccccagtgaagatccccacctgccccaggaggaggtg
ctgaagttctaccggagcatgacgctgctcaacaccatggaccgcattctctatgagtcc
cagcggcagggccggatctccttctacatgaccaactatggcgaggaggggacacatgtg
ggcagtgccgctgccttggagcgcacagacctggtgtttggccagtaccgggaggcaggt
gtgctcatgtaccgggactacccgctggagctgttcatgtcccagtgctacggcaacgtg
aatgacccaggcaagggacgccagatgcctgttcactacggctgcaaggaacgccacttc
gtcaccatttcctctccactggccacgcagatccctcaggcggtaggggcagcctatgct
gccaagcgggccaatgccaaccggattgtgatctgttactttggcgagggggcagccagt
gaaggggatgcccacgccggtttcaatttcgctgccaccctggagtgtcccatcatcttc
ttctgccggaacaatggctatgccatctccacaccaacctctgagcagtaccgtggggat
ggcatagcggctcggggccctgggtacggcatcatgtcaatccgtgtggacggcaacgat
gtgtttgctgtgtacaatgccactaaggaggcccgacggcgggctgtggctgagaaccag
cccttcctcattgaggccatgacctacaggattggccaccacagcaccagtgacgacagc
tcagcgtaccgttcggtggacgaggtcaattactgggacaagcaggaccacccaatctcg
aggctgaggcagtacctgctgaaccagggttggtgggatgaggaacaggagaaggcctgg
cggaagcagtcacgaaagaaggtcatggaagcctttgagcaggctgagcggaagctaaag
ccgaacccaagcctcctcttctccgatgtgtaccaggagatgcccgcccagctccgcagg
cagcaggagtcgctggcacggcacctgcagacttacggggagcactaccccctggaccac
tttgacaagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Chemical substance (22)   
   KEGG COMPOUND (22)   
Chemical reaction (15)   
   KEGG ENZYME (1)   
   KEGG REACTION (14)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (5)   
   RefSeq(pep) (5)   
DNA sequence (13)   
   RefSeq(nuc) (5)   
   GenBank (4)   
   EMBL (4)   
Protein domain (4)   
   Pfam (4)   
All databases (89)   

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