KEGG   Mus musculus (house mouse): 12235
Entry
12235             CDS       T01002                                 
Symbol
Bub1, Bub1a, D2Xrf87
Name
(RefSeq) BUB1, mitotic checkpoint serine/threonine kinase
  KO
K02178  checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04110  Cell cycle
mmu04114  Oocyte meiosis
mmu04914  Progesterone-mediated oocyte maturation
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    12235 (Bub1)
   04114 Oocyte meiosis
    12235 (Bub1)
 09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    12235 (Bub1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    12235 (Bub1)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mmu03036]
    12235 (Bub1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     12235 (Bub1)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: Other
  BUB family
   12235 (Bub1)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Core SAC proteins
     12235 (Bub1)
SSDB
Motif
Pfam: Mad3_BUB1_I Pkinase PK_Tyr_Ser-Thr Mad3_BUB1_I_2
Other DBs
NCBI-GeneID: 12235
NCBI-ProteinID: NP_033902
MGI: 1100510
Ensembl: ENSMUSG00000027379
UniProt: O08901 A0A8I4YXJ8
Position
2:complement(127642117..127673790)
AA seq 1058 aa
MDNLENVFRMFEAHMQSYTGNDPLGEWESFIKWVEENFPDNKEYLMTLLEHLMKEFLHKK
NYHNDSRFINYCLKFAEYNSDRHQFFEFLYNQGIGTKSSYIYMSWAGHLEAQGELQHASA
IFQTGIHNEAEPKELLQQQYRLFQARLTGIHLPAQATTSEPLHSAQILNQVMMTNSSPEK
NSACVPRSQGSECSGVASSTCDEKSNMEQRVIMISKSECSVSSSVAPKPEAQQVMYCKEK
LIRGDSEFSFEELRAQKYNQRKKHEQWVSEDRNYMKRKEANAFEEQLLKQKMDELHKKLH
QVVELSHKDLPASENRPDVSLVCVGQNTCSQQELRGPSLSSISHQTSESSGEKPQEEPSV
PLMVNAVNSTLLFPAANLPALPVPVSGQSLTDSRCVNQSVHEFMPQCGPETKEVCETNKV
ASINDFHTTPNTSLGMVQGTPCKVQPSPTVHTKEALGFIMDMFQAPTLPDISDDKDEWPS
LDQNEDAFEAQFQKNAVSSGDWGVKKIMTLSSAFPIFEDGNKENYGLPQPKNKPLGARTF
GERSLSKYSSRSNEMPHTDEFMDDSTVCGIRCNKTLAPSPKSIGDFTSAAQLSSTPFHKF
PADLVQIPEDKENVVATQYTHMALDSCKENIVDLSKGRKLGPIQEKISASLPCPSQPATG
GLFTQEAVFGLEAFKCTGIDHATVEDLSDANAGLQVECVQTLGNVNAPSFTVENPWDDEL
ILKLLSGLSKPVTSYSNTFEWQSKLPAIKTKTEYQLGSLLVYVNHLLGEGAFAQVFEAIH
GDVRNAKSEQKCILKVQRPANSWEFYIGMQLMERLKPEVHHMFIKFYSAHLFKNGSILVG
ELYSYGTLLNVINLYKNTSEKVMPQALVLTFAIRMLYMVEQVHSCEIIHGDIKPDNFILG
HRFLEQADEDLATGLALIDLGQSIDMKLFPKGTVFTGKCETSGFQCPEMLSNKPWNYQID
YFGVAATIYCMLFGSYMKVKNEGGVWKPEGLFRRLPHLDMWEEFFHIMLNIPDCHNLPSL
DFLRQNMKKLLEQQYSNKIKTLRNRLIVMLSEYKRSRK
NT seq 3177 nt   +upstreamnt  +downstreamnt
atggacaacctagaaaatgtctttcgcatgtttgaagcccatatgcaaagctacacgggt
aatgacccacttggagaatgggaaagctttataaagtgggtagaagagaattttcctgac
aataaagaatacttgatgacattattagaacatttaatgaaggaatttttacataagaag
aactaccacaatgattcaagattcatcaattattgcttaaaatttgctgagtacaacagt
gaccgtcatcagttttttgagtttctgtacaaccagggaattggaaccaagtcatcatat
atatacatgtcctgggcagggcatctggaagcccagggagagctgcagcatgccagtgct
atttttcagacaggaattcacaatgaggctgaacctaaagaactactacagcaacaatac
aggctattccaagcacgccttactggaatccatttgccagctcaagctacaacctcagaa
cctttgcatagtgcacagattttaaaccaagttatgatgacaaactcaagtccagaaaaa
aactcagcctgtgttcctaggagtcagggttcagaatgttctggtgtggcatcttccact
tgtgatgaaaagtctaatatggaacaaagggtgatcatgatttccaagtcagaatgctct
gtcagctcatctgtggcacccaagcctgaggctcagcaagttatgtactgcaaggaaaag
cttattcgtggagattcagaattttcttttgaagaactgagagcccagaaatataatcaa
aggaagaagcatgagcagtgggttagtgaagacagaaattatatgaaaaggaaagaagca
aatgcttttgaagagcaattattaaaacagaaaatggatgaacttcacaagaaattgcat
caagtggtggaattgtcacacaaggaccttcctgcttctgagaacaggcctgatgttagt
ctagtatgtgttggacaaaatacttgctcccagcaggaattgaggggtccaagtctttca
tccatcagtcatcagacctcagagagttcaggagagaaaccacaggaagaaccttctgtt
cctcttatggtaaatgctgttaacagcactttgctgttcccagctgccaacctgccagct
cttcctgttcctgtaagtggccagtcattgacagactccagatgtgtgaatcaaagtgtt
catgaattcatgccacagtgtggaccagaaacaaaagaagtgtgtgaaacaaataaagtt
gccagcattaatgattttcatacaactccaaacacatcattgggaatggttcaaggaaca
ccatgcaaagtgcagccatcaccaactgtccacaccaaggaagcattaggtttcatcatg
gacatgtttcaggctccaacacttcctgacatttctgatgataaagatgaatggccatct
ctggaccaaaatgaagatgcatttgaagcccagtttcaaaaaaatgcagtatcttcggga
gattggggagttaaaaaaattatgactttgtcatctgcttttcctatttttgaagatgga
aacaaagaaaattatggcttaccacagcctaaaaataagcccttaggagctaggaccttt
ggagaacgatctctcagtaaatattcctcgagatcaaatgaaatgcctcacactgatgag
tttatggatgattcaacagtatgtggtattcgctgcaacaaaactctagctcccagtcct
aaaagtataggagactttacatctgctgcccaactttcgtctacaccattccacaaattt
ccagcagatttagtacagattccagaagataaagaaaatgtggtagccacacagtataca
catatggctttggattcttgtaaagaaaacatagtggacctctcaaaaggcagaaagctt
gggccaattcaagagaaaatttcagcatctttaccctgtcctagtcagcctgccacaggt
ggtttgttcacccaggaagcagtgttcggccttgaggcttttaaatgcacaggcattgac
catgcgacagtggaagacctatccgatgccaatgctgggctccaagttgaatgcgtgcag
acacttggaaatgtcaatgctccaagctttactgttgagaacccatgggatgacgaattg
attcttaaacttctctctggactttctaagccagttacttcctattcaaatacttttgag
tggcagagtaaacttccagccatcaagaccaagacagaatatcaattgggttctttgctg
gtctatgtgaatcaccttcttggagaaggagcctttgctcaagtctttgaagctattcat
ggagatgtgagaaatgccaaaagtgaacagaaatgcattttgaaggtgcagagacctgcc
aactcctgggaattctacattgggatgcagctgatggaaagactaaagccagaagtacat
cacatgttcatcaagttttattctgctcatttattcaagaatggcagcatattagtaggg
gaactctacagctatgggacgttactaaatgtcattaacctctataaaaatacctctgaa
aaagtgatgccccaggctcttgtcctcactttcgctatcagaatgctttacatggttgaa
caagtccacagctgcgaaatcattcatggagacattaagccagataacttcatactagga
cacagatttttggaacaggctgatgaagacttagctaccggcttggcattgattgacctg
ggtcagagtatagatatgaaacttttccctaaaggaactgtatttacaggaaaatgtgaa
acatctggttttcagtgtcctgagatgctcagtaacaagccatggaactaccagattgat
tactttggagttgctgcaacaatatactgtatgctctttggctcttacatgaaagtaaaa
aatgaaggaggagtctggaaacctgaaggtctttttagaaggcttcctcatttggatatg
tgggaggaattttttcacatcatgttgaatataccggattgtcataatcttccatctttg
gattttctgagacagaatatgaagaaattacttgaacaacagtattccaacaagattaag
accttgcgtaataggctaattgtgatgctttcagaatataagcgttcaagaaaataa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (39)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (31)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (20)   
   RefSeq(nuc) (4)   
   GenBank (8)   
   EMBL (8)   
Protein domain (4)   
   Pfam (4)   
All databases (79)   

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