KEGG   Mus musculus (house mouse): 12236
Entry
12236             CDS       T01002                                 
Symbol
Bub1b, BUBR1
Name
(RefSeq) BUB1B, mitotic checkpoint serine/threonine kinase
  KO
K06637  mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04110  Cell cycle
mmu05166  Human T-cell leukemia virus 1 infection
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    12236 (Bub1b)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    12236 (Bub1b)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    12236 (Bub1b)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mmu03036]
    12236 (Bub1b)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     12236 (Bub1b)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: Other
  BUB family
   12236 (Bub1b)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Core SAC proteins
     12236 (Bub1b)
SSDB
Motif
Pfam: Mad3_BUB1_I Pkinase PK_Tyr_Ser-Thr Mad3_BUB1_II Mad3_BUB1_I_2
Other DBs
NCBI-GeneID: 12236
NCBI-ProteinID: NP_033903
MGI: 1333889
Ensembl: ENSMUSG00000040084
UniProt: Q9Z1S0 Q3UZD6
Position
2:118428684..118472073
AA seq 1052 aa
MAEASEAMCLEGAEWELSKENIQPLRHGRVMSTLQGALAKQESAGHTALQQQKRAFESEI
RFYSGDDPLDVWDRYINWTEQNYPQGGKESNMSALVERAIEALQGETRYYNDPRFLSLWI
KLGHLCNEPLDMYSYLQSQGIGVSLAQFYISWAEEYEARENFKKADIIFQEGIERKAEPL
DRLQSQHRQFQSRVSRQAFLALGNEEEEALEPSEPQRSSLAELKSRGKKMARAPISRVGG
ALKAPGQSRGFLNAVPQPVHGNRRITVFDENADTASRTELSKPVAQPWMAPPVPRAKENE
LQPGPWSTDRPAGRRPHDNPASVTSIPSVLPSFTPYVEESAQQTVMTPCKIEPSINHVLS
TRKPGREEGDPLQRVQSHQQGCEEKKEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKER
REAELLTSAKKREEMQKQIEEMERRLKAMQAVQQEGAGGQQEEKMPTEDPARLQIASGPQ
EMSGVPLSCSICPLSSNPREISPAENILQEQPDSKGSSMPFSIFDESLSDKKDKSPATGG
PQVLNAQRRPLSVLKTTEVGTTNEDVSPDICDELTELEPLSEDAIITGFRNVTLCPNPED
TCDFARAARLASTPFHEILSSKGIAADPEGLLQEEDLDGKAAEAHHTVHHQALIIKKLSP
IIEESREATHSSGFSRSSSSAPSTSSIKGFQLLEKLELTNDGAEDAIQSPWCSQYRLQLL
KSLLELSAFAEFSVEDRPMPVLEIGKEIELGPEDYVIKQEHLTCDDYRLFWVAPRSSAEL
TMIKASSQPIPWDFYINLKLKERLNEDYDQLCSCCQYQDGHVVWYQYINCSTLQNLLQHS
EFVTHEIIVLIIYNLLTIVEKLHRAEIVHGDLSPRSLILRNRIHDPYDYVNKDDHAVRIM
DFSYSVDLRVQLDAFAYSGFRTAQILEGQKILANCSSPYHVDLLGIADLAHLLLFKEHLH
VFWDGLLWKLSQSTSELKDSELWNKFFVRILNASDKSTVSVLGELAAEMGGAFDATFHSH
LNRALWKLGKTISPEALLTQQDKQPGGSQSPA
NT seq 3159 nt   +upstreamnt  +downstreamnt
atggcggaggcgagtgaagccatgtgcctggagggagcagagtgggagctgagtaaagaa
aacatacagcccttacggcacgggcgggtcatgtccacacttcagggagctttggcaaag
caagagtcagccggccacactgctctgcagcagcagaaacgggcatttgaatctgaaatc
cgcttttactctggagatgaccctctggatgtgtgggacagatatattaattggacagaa
cagaactaccctcaaggggggaaagagagtaacatgtcagcgttagtggagagagcgata
gaagcactccaaggagagacgcgctattataatgacccccgctttctcagtctctggatc
aaattgggacatttgtgcaatgaacctttggatatgtacagctatttacaaagccaagga
attggcgtttcccttgcccagttctatatttcatgggctgaagaatacgaagctagagaa
aatttcaagaaagcggacataatattccaggaagggattgaacgcaaggctgagcccctg
gacagactgcagtcccagcacagacagttccagtctcgagtgtcgcgacaagctttcttg
gcccttgggaatgaagaggaggaggctttggagccttctgaaccacagagaagctcgcta
gctgagctgaagagcagagggaagaagatggccagagcgcccatcagccgtgtcggaggt
gctctgaaagctccaggtcagagcagagggttcctaaatgcagttccccagccagtacac
ggtaatcgcaggatcaccgtttttgatgaaaatgccgataccgcgtctagaacggagtta
tctaagcctgtagcccagccatggatggcaccccctgtgcccagggccaaagagaacgaa
cttcagccaggcccatggagcacagacaggccggcgggacgcaggcctcatgacaatcca
gcctctgtgacgtcgattcccagcgtgcttcccagctttacgccgtacgtggaagagagc
gcccagcagacagtcatgacaccatgcaagattgagcctagtatcaaccatgttctcagc
accaggaagccagggagagaagaaggagaccccttgcagagagttcagagtcatcagcaa
ggctgtgaggagaagaaggagaagatgatgtactgtaaggagaagatctatgccggagtt
ggggagttctcctttgaggagatccgagctgaagtgttccgaaagaagctgaaagaacga
agggaagccgagctgttgaccagtgcaaagaagagggaggagatgcagaagcagatcgaa
gagatggagaggaggctgaaggcaatgcaggctgttcagcaagaaggagctgggggccag
caagaagagaagatgcctacagaggacccagccagattgcagattgcttcggggcctcag
gaaatgtcgggagttcctctgtcctgttccatctgtccactaagctcgaatcctagggaa
atttcacctgctgagaacattttgcaagaacagcctgattctaaaggttccagtatgcct
ttctccatttttgatgagtctctttcagacaaaaaggacaaaagtcctgctacaggtggt
ccacaggttctcaatgcccagagaagacccctttcagttctcaaaactacagaagtgggc
accacaaatgaggatgtgtctcccgatatttgtgatgaactcacagaacttgagcctctg
agtgaagacgccatcatcactggtttcaggaacgtcactctctgtcccaaccctgaggac
acttgtgactttgctagagcagctcgtttggcatctactcctttccatgagatactgtcc
tcgaagggcatcgctgctgatcccgagggactgttgcaggaagaggatctggatgggaag
gccgccgaggctcatcacactgttcatcaccaggccctcatcataaagaaactgagccca
attattgaagagagccgtgaggccacccactcatctggcttctccaggtcttcttcctca
gctcccagtacatcctccatcaaaggctttcagcttctggaaaagctggagctgactaat
gacggggcagaagatgctattcagtcaccctggtgttcacagtatcgcctacaactgtta
aaatccctactagaattaagtgcttttgcggagttttctgtggaagaccgaccgatgcct
gtgctggaaatagggaaggagattgagttaggtcctgaggattacgtcatcaagcaagag
cacctaacatgtgacgattacaggttattctgggtggcaccaagaagctctgcagagcta
accatgataaaggcatcatctcagcctatcccgtgggatttttatatcaacctcaagttg
aaggagcgtctgaatgaggactatgaccagctttgcagctgctgtcagtaccaagatggc
catgttgtttggtaccagtatataaactgctccacccttcagaatcttctccaacacagc
gaatttgttactcatgaaataatagtgttgattatttacaacctcttgacaatcgtggag
aagctacacagagctgaaatagtacacggagacttgagtccacggagtctgatcctacga
aacagaatccacgacccctatgactatgtaaataaggacgatcacgctgtgaggatcatg
gacttctcctacagtgttgacctgagggtgcagctggatgcgtttgcctatagtggcttt
cggactgcacagatcctggaaggacaaaagatcctggctaactgttcttctccctaccat
gtagatctgttgggtatagcagacctagcgcacttactcctgttcaaggagcacctccat
gtcttctgggatggactcctctggaaacttagccagagcacctctgagctaaaagacagt
gaattgtggaataaattctttgtgcggattctgaatgccagtgacaagtccacagtgtct
gttctgggggagctggcagcagaaatgggtggggcttttgatgccacattccatagccac
ctgaacagagccctgtggaagctggggaagacaatcagcccggaagctttgctcactcag
caagacaagcagccaggcggctcccagagccctgcctaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (35)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (27)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (16)   
   RefSeq(nuc) (2)   
   GenBank (7)   
   EMBL (7)   
Protein domain (5)   
   Pfam (5)   
All databases (69)   

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