KEGG   Mus musculus (house mouse): 12265
Entry
12265             CDS       T01002                                 
Symbol
Ciita, C2ta, EG669998, Gm9475, Mhc2ta
Name
(RefSeq) class II transactivator
  KO
K08060  MHC class II transactivator [EC:2.7.11.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04612  Antigen processing and presentation
mmu05145  Toxoplasmosis
mmu05152  Tuberculosis
mmu05164  Influenza A
mmu05340  Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    12265 (Ciita)
 09160 Human Diseases
  09172 Infectious disease: viral
   05164 Influenza A
    12265 (Ciita)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    12265 (Ciita)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    12265 (Ciita)
  09163 Immune disease
   05340 Primary immunodeficiency
    12265 (Ciita)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    12265 (Ciita)
  09183 Protein families: signaling and cellular processes
   04054 Pattern recognition receptors [BR:mmu04054]
    12265 (Ciita)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     12265 (Ciita)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: Other
  TAF1 family
   12265 (Ciita)
Pattern recognition receptors [BR:mmu04054]
 Cytoplasmic pattern recognition receptors
  NOD-like receptors
   12265 (Ciita)
SSDB
Motif
Pfam: NACHT LRR_6 NLRC4_HD2 LRR_4 LRR_8 LRR_9
Other DBs
NCBI-GeneID: 12265
NCBI-ProteinID: NP_001289547
MGI: 108445
Ensembl: ENSMUSG00000022504
UniProt: P79621 Q3UU40 Q3U5G4 Q3KNE0 Q3UNW8
Position
16:10297877..10348928
AA seq 1155 aa
MNHFQAILAQVQTLLSSQKPRQVRALLDGLLEEELLSREYHCALLHEPDGDALARKISLT
LLEKGDLDLTFLSWVCNSLQAPTVERGTSYRDHGDHSLCATMDLGSPEGSYLELLNSDAD
PLHLYHLYDQMDLAGEEEIELSSEPDTDTINCDQFSKLLQDMELDEETREAYANIAELDQ
YVFQDTQLEGLSKDLFIEHIGAEEGFGENIEIPVEAGQKPQKRRFPEEHAMDSKHRKLVP
TSRTSLNYLDLPTGHIQIFTTLPQGLWQISGAGTGLSSVLIYHGEMPQVNQVLPSSSLSI
PSLPESPDRPGSTSPFTPSAADLPSMPEPALTSRVNETEDTSPSPCQEGPESSIKLPKWP
EAVERFQHSLQDKYKALPQSPRGPLVAVELVRARLERGSNKSQERELATPDWTERQLAHG
GLAEVLQVVSDCRRPGETQVVAVLGKAGQGKSHWARTVSHTWACGQLLQYDFVFYVPCHC
LDRPGDTYHLRDLLCPPSLQPLAMDDEVLDYIVRQPDRVLLILDAFEELEAQDGLLHGPC
GSLSPEPCSLRGLLAGIFQRKLLRGCTLLLTARPRGRLAQSLSKADAIFEVPSFSTKQAK
TYMRHYFENSGTAGNQDKALGLLEGQPLLCSYSHSPVVCRAVCQLSKALLEQGTEAQLPC
TLTGLYVSLLGPAAQNSPPGALVELAKLAWELGRRHQSTLQETRFSSVEVKTWAVTQGLM
QQTLETTEAQLAFSSFLLQCFLGAVWLAQCNEIKDKELPQYLALTPRKKRPYDNWLEGVP
RFLAGLVFQPRAHCLGALVEPAVAAVADRKQKVLTRYLKRLKLGTLRAGRLLELLHCAHE
TQQPGIWEHVAHQLPGHLSFLGTRLTPPDVYVLGRALETASQDFSLDLRQTGVEPSGLGN
LVGLSCVTSFRASLSDTMALWESLQQQGEAQLLQAAEEKFTIEPFKAKSPKDVEDLDRLV
QTQRLRNPSEDAAKDLPAIRDLKKLEFALGPILGPQAFPTLAKILPAFSSLQHLDLDSLS
ENKIGDKGVSKLSATFPQLKALETLNLSQNNITDVGACKLAEALPALAKSLLRLSLYNNC
ICDKGAKSLAQVLPDMVSLRVMDVQFNKFTAAGAQQLASSLQKCPQVETLAMWTPTIPFG
VQEHLQQLDARISLR
NT seq 3468 nt   +upstreamnt  +downstreamnt
atgaaccacttccaggccatcctggcccaagtacagacactgctctccagccagaagccc
aggcaggtgcgggccctcctggatggcctgctggaagaagagctgctctcacgggaatac
cactgtgccttgctgcatgagcctgatggtgatgccctggcccggaagatttccctgacc
ctgctggagaaaggggacttagacttgactttcttgagctgggtctgcaacagtctgcag
gctcccacggtagagaggggcaccagctacagggaccatggagaccatagtctgtgtgcc
accatggatctgggatctccagagggcagctacctggaactccttaacagtgatgccgac
cccctacatctctaccacctctatgaccagatggacctggctggggaggaggagatcgaa
ctcagctcagagccagacacagataccatcaactgcgaccagttcagcaagctgttgcag
gacatggaactggatgaagagacccgggaggcctatgccaacattgcggaactggatcag
tacgtgttccaggatacccagctcgagggcctgagcaaggacctcttcatagagcacatt
ggagcagaggaaggctttggtgagaacatagagatccctgtagaagcaggacagaagcct
cagaagagacgcttcccggaagagcatgctatggactcaaagcacaggaagctagtgccc
acctctaggacctcactgaactatttggatctccccactgggcacatccagatcttcacc
actctgccccagggactctggcaaatctcaggggctggcacaggtctctccagtgtccta
atctaccacggtgagatgccccaggtcaaccaagtgctcccttcaagcagcctcagtatc
cccagtctccccgagtccccagaccggcctggctccaccagccccttcacaccatctgca
gctgacctgcccagcatgcccgaacctgcgctgacctcccgtgtaaatgagacagaggac
acatctccctccccatgccaagagggtcccgagtcttccatcaagcttccaaaatggcca
gaggctgtggagcgattccagcactccctacaggacaaatacaaggcattgccccagagc
ccaaggggtcctctggtggccgtggagctggtacgggccaggctggaaagaggcagcaac
aagagccaggaaagggagctggccactcccgactggacagagcgccagctagcccacggt
ggtctggcagaggtacttcaggttgtcagtgactgcaggcgaccaggagagacacaggtg
gtcgctgtgctgggcaaggctggccagggaaagagccactgggccaggacagtgagtcac
acctgggcatgtggccagttgctacaatatgactttgtcttctatgtcccctgtcattgc
ttggatcgtcccggggacacctaccacctgcgggatctgctctgtcccccgagcctgcag
ccactggccatggatgacgaggtccttgattatatcgtgaggcagccagaccgtgttctg
ctcatcctagatgctttcgaggagctagaggcccaagatggcctcctgcacggaccctgt
ggatctctgtccccagagccctgctccctccgaggactgctggctgggatcttccagcgg
aagctactgcgaggctgcacactgctcctcacagcccggccccggggccgcctggctcag
agcctgagcaaggcagatgccatctttgaggtgcccagcttctctaccaagcaggccaag
acttacatgaggcactactttgagaactcagggacagcggggaaccaagacaaggccctg
ggcctcctggagggccagcctcttctctgcagctatagtcacagccctgttgtgtgcagg
gctgtgtgccagctctccaaggccctgctagaacagggcacagaggcccagctaccttgt
acacttacaggactctatgtcagcctgctaggtcctgcagctcagaacagtcctcccgga
gccttagtcgagctggccaagctggcctgggagctgggacgaagacaccaaagcaccttg
caagaaacccggttttcatccgtggaggtgaaaacctgggcagtgacccaaggcttgatg
cagcagaccctggagaccacggaggctcaactggccttctccagttttctgctacagtgt
ttcctgggtgctgtgtggctggcacagtgcaatgaaatcaaagacaaggagctgccacag
tacctggccttgactccgaggaagaagagaccctatgacaactggctggagggtgtacca
cgctttctggctggattagttttccagcctcgagcccactgcctgggagctctggtggag
cctgcagtggctgcagtggcggataggaaacagaaggttcttaccaggtacctgaagcgc
ctgaagctggggacactccgggcagggaggctgctggagctgctccactgtgcccacgag
acacagcaacctgggatatgggagcatgttgcacaccagctccctggccacctctccttc
ctgggcacccggctcacacccccagatgtgtatgtgctgggcagggccttggagacagcc
agccaggacttctccttggaccttcgtcagactggcgttgagccttctggactgggaaac
ctcgtgggactcagctgtgtcaccagtttcagggcctccttgagtgatacaatggcatta
tgggagtcccttcagcagcagggagaagcccagctactccaggcggcagaggagaagttc
accattgagccatttaaagccaaatccccaaaggatgtggaagacctggatcgtctcgtg
cagacccagaggctgagaaacccctcagaagatgcagccaaggatcttcctgccatccgg
gaccttaagaagctagagtttgcgttgggccccatcttgggcccccaggctttccccaca
ctggcaaagatccttccagccttctcttctctgcaacacctggacctggactcacttagt
gagaacaagatcggagacaagggtgtgtcgaagctctcagccaccttccctcagctgaag
gccctggagacgctcaacttgtcccaaaacaacatcactgatgtgggtgcctgcaagctt
gcagaagctctgccagccctagccaagtccctcctaaggctgagcttgtacaataactgc
atctgtgacaaaggagccaagagcctggcacaagtacttccggacatggtgtccctgcgt
gtgatggatgtccagttcaacaagttcacggctgccggtgcccagcaactggcctccagc
cttcagaagtgccctcaggtggaaacactggcaatgtggacacccactatcccctttggg
gttcaggaacacctgcagcagctggatgccaggatcagtctgagatga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (15)   
   UniProt (5)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (44)   
   RefSeq(nuc) (10)   
   GenBank (17)   
   EMBL (17)   
Protein domain (6)   
   Pfam (6)   
All databases (99)   

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