KEGG   Mus musculus (house mouse): 12363
Entry
12363             CDS       T01002                                 
Symbol
Casp4, CASP-11, CASP-4, Casp11, Caspl, ich-3
Name
(RefSeq) caspase 4, apoptosis-related cysteine peptidase
  KO
K04394  caspase 4 [EC:3.4.22.57 3.4.22.64]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04613  Neutrophil extracellular trap formation
mmu04621  NOD-like receptor signaling pathway
mmu05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    12363 (Casp4)
   04621 NOD-like receptor signaling pathway
    12363 (Casp4)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    12363 (Casp4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:mmu01002]
    12363 (Casp4)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.57  caspase-4
     12363 (Casp4)
    3.4.22.64  caspase-11
     12363 (Casp4)
Peptidases and inhibitors [BR:mmu01002]
 Cysteine peptidases
  Family C14: caspase family
   12363 (Casp4)
SSDB
Motif
Pfam: Peptidase_C14 CARD DUF5906
Other DBs
NCBI-GeneID: 12363
NCBI-ProteinID: NP_031635
MGI: 107700
Ensembl: ENSMUSG00000033538
UniProt: P70343
Structure
Position
9:5308816..5336791
AA seq 373 aa
MAENKHPDKPLKVLEQLGKEVLTEYLEKLVQSNVLKLKEEDKQKFNNAERSDKRWVFVDA
MKKKHSKVGEMLLQTFFSVDPGSHHGEANLEMEEPEESLNTLKLCSPEEFTRLCREKTQE
IYPIKEANGRTRKALIICNTEFKHLSLRYGANFDIIGMKGLLEDLGYDVVVKEELTAEGM
ESEMKDFAALSEHQTSDSTFLVLMSHGTLHGICGTMHSEKTPDVLQYDTIYQIFNNCHCP
GLRDKPKVIIVQACRGGNSGEMWIRESSKPQLCRGVDLPRNMEADAVKLSHVEKDFIAFY
STTPHHLSYRDKTGGSYFITRLISCFRKHACSCHLFDIFLKVQQSFEKASIHSQMPTIDR
ATLTRYFYLFPGN
NT seq 1122 nt   +upstreamnt  +downstreamnt
atggctgaaaacaaacaccctgacaaaccacttaaggtgttggaacagctgggcaaagaa
gtccttacggagtacctagaaaaattagtacaaagcaatgtactgaaattaaaggaggaa
gataaacaaaaatttaacaatgctgaacgcagtgacaagcgttgggtttttgtagatgcc
atgaaaaagaaacacagcaaagtaggtgaaatgcttctccagacattcttcagtgtggac
ccaggcagccaccatggtgaagctaatctggaaatggaggaaccagaagaatcattgaac
actctcaagctttgttcccctgaagagttcacaaggctttgcagagaaaagacacaagaa
atttacccaataaaggaggccaatggccgtacacgaaaggctcttatcatatgcaataca
gagttcaaacatctctcactgaggtatggggctaactttgacatcattggtatgaaaggc
cttcttgaagacttaggctacgatgtggtggtgaaagaggagcttacagcagagggcatg
gagtcagagatgaaagactttgctgcactctcagaacaccagacatcagacagcacattc
ctggtgctaatgtctcatggcacactgcatggcatttgtggaacaatgcacagtgaaaaa
actccagatgtgctacagtatgataccatctatcagatattcaacaattgccactgtcca
ggtctacgagacaaacccaaagtcatcattgtgcaggcctgcagaggtgggaactctgga
gaaatgtggatcagagagtcttcaaaaccccagttgtgcagaggtgtagatctacctagg
aatatggaagctgatgctgtcaagctgagccacgtggagaaggacttcattgccttctac
tctacaaccccacatcacttgtcctaccgagacaaaacaggaggctcttacttcatcact
agactcatttcctgcttccggaaacatgcttgctcttgtcatctctttgatatattcctg
aaggtgcaacaatcatttgaaaaggcaagtattcattcccagatgcccaccattgatcgg
gcaaccttgacgagatatttctacctctttcctggcaactga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (2)   
   KEGG ENZYME (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (31)   
   RefSeq(nuc) (9)   
   GenBank (11)   
   EMBL (11)   
3D Structure (5)   
   PDB (5)   
Protein domain (3)   
   Pfam (3)   
All databases (80)   

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