KEGG   Mus musculus (house mouse): 12371
Entry
12371             CDS       T01002                                 
Symbol
Casp9, APAF-3, CASP-9, Caspase-9, ICE-LAP6, Mch6
Name
(RefSeq) caspase 9
  KO
K04399  caspase 9 [EC:3.4.22.62]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu01524  Platinum drug resistance
mmu04115  p53 signaling pathway
mmu04151  PI3K-Akt signaling pathway
mmu04210  Apoptosis
mmu04215  Apoptosis - multiple species
mmu04370  VEGF signaling pathway
mmu04919  Thyroid hormone signaling pathway
mmu05010  Alzheimer disease
mmu05012  Parkinson disease
mmu05014  Amyotrophic lateral sclerosis
mmu05016  Huntington disease
mmu05020  Prion disease
mmu05022  Pathways of neurodegeneration - multiple diseases
mmu05134  Legionellosis
mmu05145  Toxoplasmosis
mmu05152  Tuberculosis
mmu05160  Hepatitis C
mmu05161  Hepatitis B
mmu05162  Measles
mmu05163  Human cytomegalovirus infection
mmu05164  Influenza A
mmu05167  Kaposi sarcoma-associated herpesvirus infection
mmu05168  Herpes simplex virus 1 infection
mmu05169  Epstein-Barr virus infection
mmu05170  Human immunodeficiency virus 1 infection
mmu05200  Pathways in cancer
mmu05210  Colorectal cancer
mmu05212  Pancreatic cancer
mmu05213  Endometrial cancer
mmu05215  Prostate cancer
mmu05222  Small cell lung cancer
mmu05223  Non-small cell lung cancer
mmu05416  Viral myocarditis
mmu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04370 VEGF signaling pathway
    12371 (Casp9)
   04151 PI3K-Akt signaling pathway
    12371 (Casp9)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    12371 (Casp9)
   04215 Apoptosis - multiple species
    12371 (Casp9)
   04115 p53 signaling pathway
    12371 (Casp9)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    12371 (Casp9)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    12371 (Casp9)
  09162 Cancer: specific types
   05210 Colorectal cancer
    12371 (Casp9)
   05212 Pancreatic cancer
    12371 (Casp9)
   05215 Prostate cancer
    12371 (Casp9)
   05213 Endometrial cancer
    12371 (Casp9)
   05222 Small cell lung cancer
    12371 (Casp9)
   05223 Non-small cell lung cancer
    12371 (Casp9)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    12371 (Casp9)
   05161 Hepatitis B
    12371 (Casp9)
   05160 Hepatitis C
    12371 (Casp9)
   05164 Influenza A
    12371 (Casp9)
   05162 Measles
    12371 (Casp9)
   05168 Herpes simplex virus 1 infection
    12371 (Casp9)
   05163 Human cytomegalovirus infection
    12371 (Casp9)
   05167 Kaposi sarcoma-associated herpesvirus infection
    12371 (Casp9)
   05169 Epstein-Barr virus infection
    12371 (Casp9)
  09171 Infectious disease: bacterial
   05134 Legionellosis
    12371 (Casp9)
   05152 Tuberculosis
    12371 (Casp9)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    12371 (Casp9)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    12371 (Casp9)
   05012 Parkinson disease
    12371 (Casp9)
   05014 Amyotrophic lateral sclerosis
    12371 (Casp9)
   05016 Huntington disease
    12371 (Casp9)
   05020 Prion disease
    12371 (Casp9)
   05022 Pathways of neurodegeneration - multiple diseases
    12371 (Casp9)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    12371 (Casp9)
   05416 Viral myocarditis
    12371 (Casp9)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    12371 (Casp9)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mmu01009]
    12371 (Casp9)
   01002 Peptidases and inhibitors [BR:mmu01002]
    12371 (Casp9)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.62  caspase-9
     12371 (Casp9)
Protein phosphatases and associated proteins [BR:mmu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     12371 (Casp9)
Peptidases and inhibitors [BR:mmu01002]
 Cysteine peptidases
  Family C14: caspase family
   12371 (Casp9)
SSDB
Motif
Pfam: Peptidase_C14 CARD CARD_2
Other DBs
NCBI-GeneID: 12371
NCBI-ProteinID: NP_056548
MGI: 1277950
Ensembl: ENSMUSG00000028914
UniProt: Q8C3Q9
Position
4:141520923..141543289
AA seq 454 aa
MDEADRQLLRRCRVRLVSELQVAELWDALLSRELFTRDMIEDIQQAGSGSRRDQARQLVT
DLETRGRQALPLFISCLEDTGQGTLASLLQSGRQAAKQDPEAVKPLDHLVPVVLGPMGLT
AKEQRVVKLDPSQPAVGNLTPVVLGPEELWPARLKPEVLRPETPRPVDIGSGGAHDVCVP
GKIRGHADMAYTLDSDPCGHCLIINNVNFCPSSGLGTRTGSNLDRDKLEHRFRWLRFMVE
VKNDLTAKKMVTALMEMAHRNHRALDCFVVVILSHGCQASHLQFPGAVYGTDGCSVSIEK
IVNIFNGSGCPSLGGKPKLFFIQACGGEQKDHGFEVACTSSQGRTLDSDSEPDAVPYQEG
PRPLDQLDAVSSLPTPSDILVSYSTFPGFVSWRDKKSGSWYIETLDGILEQWARSEDLQS
LLLRVANAVSAKGTYKQIPGCFNFLRKKLFFKTS
NT seq 1365 nt   +upstreamnt  +downstreamnt
atggacgaggcggaccggcagctcctgcggcgatgcagggtgcgcctagtgagcgagctg
caagtcgcggagctctgggacgctctgctgagtcgagagctcttcacgcgcgacatgatc
gaggatattcagcaggcaggatctgggtctcggcgggatcaggccaggcagctggtcaca
gaccttgagacccgagggaggcaggcccttcctctcttcatctcctgcttagaggacaca
ggccaaggcaccctggcttcactcttgcaaagcggtcggcaagcagccaagcaggatcca
gaggctgttaaacccctagaccacctggtgcctgtggtcctgggaccaatgggactcaca
gcaaaggagcagagagtagtgaagctggacccgtcacagcctgccgtgggaaacctcacc
ccagtggtgctggggccagaagagctctggcctgctcggctcaagccagaggttctcaga
ccagaaacacccaggcccgtggacattggttctggcggagctcatgatgtctgtgttcca
gggaagatcaggggacatgcagatatggcatacaccctggattcggatccctgtggccac
tgcctcatcatcaacaatgtgaacttctgcccttcctcggggctcggcacacgcacgggc
tccaacttggaccgtgacaaacttgagcaccgattccgctggctgcgcttcatggtggag
gtgaagaacgacctgactgccaagaaaatggtcacggctttgatggagatggcacaccgg
aaccaccgtgccctggactgctttgtggtggtcatcctctctcatggctgccaggccagc
cacctccagttcccgggtgctgtctatgggacagatggatgctccgtgtccattgagaaa
attgtgaatatcttcaacgggagcggctgccccagcctgggagggaagcccaagctcttc
ttcatccaggcctgcggtggtgagcagaaagaccatggctttgaggtggcctgcacttcc
tctcaaggcaggaccttggacagtgactctgagccagatgctgtcccctatcaggaaggc
ccaaggcccttggaccagctggatgctgtgtcaagtttgcctacccccagtgacatcctt
gtgtcctactccaccttcccaggttttgtctcctggagggacaagaaaagtggctcctgg
tacatcgagaccttggatggcattctggagcagtgggctcgctctgaagacctgcagtcc
ctccttctcagggttgccaatgctgtttctgcgaaagggacttacaagcagattcctggc
tgttttaacttcctccggaaaaagctgttttttaaaacttcatga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (34)   
   KEGG PATHWAY (34)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (31)   
   RefSeq(nuc) (3)   
   GenBank (14)   
   EMBL (14)   
Protein domain (3)   
   Pfam (3)   
All databases (95)   

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