KEGG   Mus musculus (house mouse): 12385
Entry
12385             CDS       T01002                                 
Symbol
Ctnna1, 2010010M04Rik, Catna1
Name
(RefSeq) catenin alpha 1
  KO
K05691  catenin alpha
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04390  Hippo signaling pathway
mmu04520  Adherens junction
mmu04670  Leukocyte transendothelial migration
mmu05100  Bacterial invasion of epithelial cells
mmu05200  Pathways in cancer
mmu05213  Endometrial cancer
mmu05226  Gastric cancer
mmu05412  Arrhythmogenic right ventricular cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    12385 (Ctnna1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    12385 (Ctnna1)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    12385 (Ctnna1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    12385 (Ctnna1)
  09162 Cancer: specific types
   05226 Gastric cancer
    12385 (Ctnna1)
   05213 Endometrial cancer
    12385 (Ctnna1)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    12385 (Ctnna1)
  09166 Cardiovascular disease
   05412 Arrhythmogenic right ventricular cardiomyopathy
    12385 (Ctnna1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:mmu04812]
    12385 (Ctnna1)
Cytoskeleton proteins [BR:mmu04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Cross-linking proteins
     12385 (Ctnna1)
SSDB
Motif
Pfam: Vinculin GIT1_C I_LWEQ
Other DBs
NCBI-GeneID: 12385
NCBI-ProteinID: NP_033948
MGI: 88274
Ensembl: ENSMUSG00000037815
UniProt: P26231 Q545R0
Structure
Position
18:35251955..35387829
AA seq 906 aa
MTAVHAGNINFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHV
LAASVEQATENFLEKGDKIAKESQFLKEELVVAVEDVRKQGDLMKSAAGEFADDPCSSVK
RGNMVRAARALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKAL
KPEVDKLNIMAAKRQQELKDVGNRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKAN
RDLIYKQLQQAVTGISNAAQATASDDAAQHQGGSGGELAYALNNFDKQIIVDPLSFSEER
FRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNAGRKER
SDALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYA
QVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLA
QENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDR
TAGAIRGRAARVIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSS
DPAQPMDENEFIDASRLVYDGIRDIRKAVLMIRTPEELDDSDFETEDFDVRSRTSVQTED
DQLIAGQSARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMC
MIMMEMTDFTRGKGPLKNTSDVISAAKKIAEAGSRMDKLGRTIADHCPDSACKQDLLAYL
QRIALYCHQLNICSKVKAEVQNLGGELVVSGVDSAMSLIQAAKNLMNAVVQTVKASYVAS
TKYQKSQGMASLNLPAVSWKMKAPEKKPLVKREKQDETQTKIKRASQKKHVNPVQALSEF
KAMDSI
NT seq 2721 nt   +upstreamnt  +downstreamnt
atgactgccgtccacgcaggcaacataaacttcaaatgggaccccaaaagtctggagatt
aggactctggctgttgaaagactgttggagcctcttgttacacaggttacaaccctggta
aacaccaatagtaaagggccgtctaataaaaagagaggccgttctaagaaggcccatgtt
ttggctgcatctgttgaacaagcaactgagaatttcttggaaaagggggataaaattgca
aaagagagccagtttctcaaggaggagcttgtggttgctgtagaagatgttcgaaaacaa
ggagatttgatgaagagcgctgctggggagtttgcagatgatccatgctcttctgtgaag
cgaggcaacatggtccgggcagctcgagctttgctctctgccgtcacccggctgctgatt
ctggctgacatggcagatgtctacaaattacttgttcagctgaaagttgtggaagatggt
atattgaaactgaggaatgctggcaatgaacaagacttagggatacagtacaaagctctg
aaaccagaagtagataagctgaacatcatggcagcaaaaagacaacaggaactaaaagat
gtgggcaatcgtgatcagatggctgcagctagaggaatcctgcagaaaaatgttccaatc
ctctatactgcatcccaggcatgtctacaacaccctgatgttgcagcctataaggccaac
cgggacttgatatacaagcagctgcagcaggccgtcacaggaatttctaatgcagcccag
gctactgcatcagatgatgctgcccagcaccagggtggcagtggcggagagctggcatac
gctctcaacaactttgataaacaaatcattgtggaccccttgagcttcagcgaggagcgc
tttaggccgtccctggaggagcgcctggaaagcattattagtggggctgccctgatggct
gactcatcctgcacacgtgatgaccgtcgggagcgcattgtggcagagtgtaatgctgtc
cgccaggctctacaggacctgctctcagaatacatgggcaacgctggacgtaaagaaaga
agtgatgcactcaactctgcaatagataaaatgaccaagaagaccagggacttgcgtaga
cagcttcgcaaagctgtcatggaccacgtatcagattctttcctggagaccaatgtccct
ctattagtactgattgaagctgcaaagaatggaaatgagaaagaagttaaggaatatgcc
caagtttttcgtgaacatgccaacaaactgattgaggttgccaacctggcctgttcaatc
tccaacaatgaagaaggcgtgaagcttgtccgaatgtctgcaagccagttagaagcgctg
tgtcctcaggttatcaatgctgcattggcgttggcagcaaagccgcagagtaaactggcc
caagagaacatggatctttttaaagagcaatgggaaaagcaagtccgtgttctcacagat
gctgttgatgacattacttccatcgatgacttcttggctgtctcagagaaccacatttta
gaagatgtgaacaagtgtgttattgctctccaagagaaagacgtggatgggctggatcgc
actgccggtgccatccgaggccgggcagcccgagtcattcatgtagtcacctcagagatg
gacaactacgagccaggagtttacacagagaaggttctggaagccaccaagctcctctcc
aacacagtcatgccgcgcttcactgagcaggtggaagcagctgtggaagccctcagctcg
gacccggcccagcccatggatgagaatgagttcatcgacgcctcccgtctggtgtacgac
ggcatccgggacatccggaaagcagtgctgatgatcaggacccccgaggagttggacgac
tctgacttcgagactgaagactttgatgtcagaagcaggaccagtgtccagacagaagat
gaccagctgatagctggccagagcgcccgggcgatcatggctcagcttcctcaggagcaa
aaagcaaagattgcagaacaggtggccagtttccaggaagagaagagcaagctggatgct
gaagtgtccaagtgggatgacagtggcaatgacatcattgtgctggccaagcagatgtgc
atgatcatgatggagatgaccgacttcacccgaggcaaaggtccactcaaaaacacctct
gacgtgatcagtgctgccaagaaaattgcggaggcgggatccaggatggacaagctcggc
cggaccatcgcagaccattgcccagactcggcatgcaagcaggacctgctggcctacctt
cagcgcatcgctctctactgccaccagctcaacatctgcagcaaagtcaaggctgaagta
cagaaccttggtggagagctggtcgtctctggggtggacagcgccatgtccctgatccag
gcggccaagaacttgatgaatgctgttgtgcagacagtgaaggcgtcctacgtggcttcc
accaaataccagaagtcacaggggatggcttccttgaaccttcctgctgtgtcatggaag
atgaaggcccctgagaagaagccgttggtgaagagagagaagcaggatgagacgcagacc
aagattaaacgagcttctcagaagaaacacgtgaacccagtgcaggccctgagcgagttc
aaagccatggacagcatctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (8)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (40)   
   RefSeq(nuc) (4)   
   GenBank (18)   
   EMBL (18)   
3D Structure (10)   
   PDB (10)   
Protein domain (3)   
   Pfam (3)   
All databases (90)   

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